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Chest:吸水烟与冠状动脉钙化的关系

2019-02-10 xing.T MedSci原创

由此可见,只吸水烟与CAC的存在和程度相关,CAC的风险增加两倍,归为高CHD风险类别的风险是其他危险因素的三倍。

吸水烟越来越受欢迎,部分原因在于与吸烟相比减少了伤害。近日,呼吸领域权威杂志chest上发表了一篇研究文章,该研究在社区样本中评估了水烟与冠状动脉钙化(CAC)(冠心病(CHD)风险的标志)之间的关系。

研究人员从黎巴嫩和卡塔尔的社区招募了175名只吸水烟者和170名35岁以上的非吸烟者,使用经过验证的问卷评估吸水烟情况,并使用多维计算机断层扫描评估CAC评分。研究人员使用针对CHD危险因素调整的回归分析评估吸水烟与有无CAC和程度之间的关联。

41%的吸水烟者存在CAC,而28%非吸烟者存在CAC,p=0.01,在吸水烟者中平均CAC为90.6 Agatston单位(AU)(SD=400.3),在非吸烟者中平均CAC为52.4 AU(SD=218.6)。在调整后的分析中,吸水烟者患CAC的调整几率明显较高(OR=2.20,95%CI[1.20-4.01],p=0.01);并且CAC>300AU(OR=3.41,95%CI[1.08-10.77],p=0.04)或相比于非吸烟者CAC>75%年龄、性别和种族预测值(OR=3.11,95%CI[1.55-6.24],p=0.001)定义为高CHD风险类别。CAC程度与吸烟持续时间(β=0.17/年,95%CI[0.05-0.29],p=0.004)或吸烟持续时间与每日吸水烟数(β)的乘积显著相关(β=0.04/水烟每年,95%CI[0.003-0.07],p=0.03)。

由此可见,只吸水烟与CAC的存在和程度相关,CAC的风险增加两倍,归为高CHD风险类别的风险是其他危险因素的三倍。

原始出处:

Hassan A. Chami,et al.The Association of Waterpipe Smoking and Coronary Artery Calcium in a Community-Based Sample.chest.2019.https://journal.chestnet.org/article/S0012-3692(19)30028-5/fulltext

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    2019-04-22 仁医06
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1663288, encodeId=932f1663288d8, content=<a href='/topic/show?id=4bae3334873' target=_blank style='color:#2F92EE;'>#动脉钙化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33348, encryptionId=4bae3334873, topicName=动脉钙化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d1d25597695, createdName=1249897bm45(暂无昵称), createdTime=Wed Feb 13 15:11:00 CST 2019, time=2019-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1973521, encodeId=651e19e3521d9, content=<a href='/topic/show?id=3e72309122a' target=_blank style='color:#2F92EE;'>#冠状动脉钙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30912, encryptionId=3e72309122a, topicName=冠状动脉钙)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Thu Feb 14 22:11:00 CST 2019, time=2019-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051344, encodeId=3eff205134422, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Mon Jan 20 12:11:00 CST 2020, time=2020-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1929543, encodeId=d049192954366, content=<a href='/topic/show?id=9e604625ab' target=_blank style='color:#2F92EE;'>#Chest#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4625, encryptionId=9e604625ab, topicName=Chest)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Apr 22 05:11:00 CST 2019, time=2019-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1269203, encodeId=00cc12692038a, content=<a href='/topic/show?id=686830913f7' target=_blank style='color:#2F92EE;'>#冠状动脉钙化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30913, encryptionId=686830913f7, topicName=冠状动脉钙化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Tue Feb 12 11:11:00 CST 2019, time=2019-02-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502954, encodeId=cb5f1502954ad, content=<a href='/topic/show?id=57d66420e59' target=_blank style='color:#2F92EE;'>#水烟#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64207, encryptionId=57d66420e59, topicName=水烟)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Tue Feb 12 11:11:00 CST 2019, time=2019-02-12, status=1, ipAttribution=)]
    2019-02-12 仁医06
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