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J Allergy Clin Immunol:鼻病毒和哮喘有关?

2016-06-27 Mechront 译 MedSci原创

研究数据表明,儿童早期经历鼻病毒和吸入性过敏原过敏与青春期持续性哮喘有关。威斯康星大学儿科和医学部门的Frederick J. Rubner博士和同事对217名儿童进行了研究,从出生随访到13岁。在前三年,Rubner和同事检查了参与者病因和鼻病毒、呼吸道合胞病毒感染时间,并确定过敏原的模式。在13岁的时候,研究人员评估了哮喘的诊断,并确定诊断是否与他们在3岁时的研究结果有关。Rubner及其同事

研究数据表明,儿童早期经历鼻病毒和吸入性过敏原过敏与青春期持续性哮喘有关。

威斯康星大学儿科和医学部门的Frederick J. Rubner博士和同事对217名儿童进行了研究,从出生随访到13岁。在前三年,Rubner和同事检查了参与者病因和鼻病毒、呼吸道合胞病毒感染时间,并确定过敏原的模式。在13岁的时候,研究人员评估了哮喘的诊断,并确定诊断是否与他们在3岁时的研究结果有关。

Rubner及其同事发现,3岁时的鼻病毒和13岁时的哮喘有关(OR = 3.3; 95% CI, 1.5-7.1),呼吸道合胞病毒在这之间没什么关系。采用多元逐步回归分析,患者年龄1岁时的吸入性过敏原过敏就与13岁的哮喘有关了(OR = 6; 95% CI, 2.5-14.4)。

“有趣的是,如果在孩子在5岁以后才出现敏感性,其患哮喘的风险跟从未出现敏感性的孩子没有什么不同,”Rubner和同事写道。“这些模式表明,致敏的时间有助于揭示未来的哮喘风险。”

原始出处:

Rubner FJ, et al.Early life rhinovirus wheezing, allergic sensitization, and asthma risk at adolescence. J Allergy Clin Immunol. 2016;doi:10.1016/j.jaci.2016.03.049.

Early rhinovirus, aeroallergen sensitization linked to asthma persistence in adolescence.Healio.June 24, 2016

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    2016-09-18 1e10c84am36(暂无匿称)

    不错哦继续关注

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=130282, encodeId=a6e513028295, content=不错哦继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 18 15:30:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=123732, encodeId=0f2d123e3257, content=关注值得学习。赞!好文有待探究。, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Sep 12 18:09:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1328903, encodeId=ef1f132890363, content=<a href='/topic/show?id=bb96232801' target=_blank style='color:#2F92EE;'>#ALL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2328, encryptionId=bb96232801, topicName=ALL)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Wed Jun 29 04:34:00 CST 2016, time=2016-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626592, encodeId=226e162659225, content=<a href='/topic/show?id=6a3b10348172' target=_blank style='color:#2F92EE;'>#鼻病毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103481, encryptionId=6a3b10348172, topicName=鼻病毒)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e59021047417, createdName=tonychen28, createdTime=Wed Jun 29 04:34:00 CST 2016, time=2016-06-29, status=1, ipAttribution=)]
    2016-09-12 ylzr123

    关注值得学习。赞!好文有待探究。

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    2016-06-29 膀胱癌
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