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Neurology:青春期BMI增加与成人卒中风险之间的相关性分析!

2017-06-29 xing.T MedSci原创

由此可见,青春期BMI增加与成年男性的缺血性卒中和脑出血风险相关。研究人员推测在青春期BMI增加较大会增加成人卒中的风险,至少部分是通过增加血压来实现。

近日,神经病学领域权威取杂志Neurology上发表了一篇系统评价文章,研究人员旨在评估青春期前儿童体重指数(BMI)以及青春期BMI变化值,2个不同的发育BMI参数,对成年男性卒中风险的作用。

在瑞典哥德堡人群为基础的研究中,这些受试者均出生于1945年至1961年,且都有在8岁时的儿童BMI和青春期BMI变化值(20岁的BMI值减去8岁时的BMI)的信息,并随访至2013年12月(n=37669)。卒中事件的信息来自于高质量的国家登记中心(918例首次卒中事件患者、672例缺血性卒中事件患者和207例脑出血事件患者)。

青春期BMI增加(每增加1个SD的风险比为1.21,95%可信区间为1.14-1.28),而不是儿童BMI,与成人卒中的风险独立相关。亚组分析显示青春期BMI增加与缺血性卒中事件(每增加1个SD的风险比为1.19;95%可信区间为1.11-1.28)和脑出血事件(每增加1个SD的风险比为1.29;95%可信区间为1.15-1.46)。青春期BMI增加较大与成年高血压的风险密切相关(每增加1个SD的比值比为1.35;95%可信区间为1.32-1.39)。

由此可见,青春期BMI增加与成年男性的缺血性卒中和脑出血风险相关。研究人员推测在青春期BMI增加较大会增加成人卒中的风险,至少部分是通过增加血压来实现。

原始出处:


Claes Ohlsson,et al. BMI increase through puberty and adolescence is associated with risk of adult stroke. Neurology. 2017. http://dx.doi.org/10.1212/WNL.0000000000004158

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    2017-07-27 yinhl1978
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    2017-07-12 jacob9231

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    0

  4. 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    2017-07-03 jacob9231

    学习了谢谢分享

    0

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    2017-06-30 184****9840

    学习了谢谢分享

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    2017-06-29 lovetcm

    越年轻越肥胖危险就越高

    0

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