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J Oral Maxillofac Surg:体外冲击波治疗对下颌骨牵张成骨的影响

2018-08-20 MedSci MedSci原创

牵张成骨术(DO)是一种确定的颅面骨骼骨延长方法,其主要缺点是长期巩固期,在此期间可能会发生多种并发症。既往研究已经提出了几种缩短巩固期的方法。本研究中个,我们评估了体外冲击波治疗(ESWT)对下颌骨DO期间骨矿化和细胞外骨基质蛋白的影响。27只大鼠接受下颌DO(潜伏期,3天;牵引期,10天; 0.5mm /天),根据ESWT应用的时间分为3组:I组(对照组)未接受治疗,而组II和III分别在主动

牵张成骨术(DO)是一种确定的颅面骨骼骨延长方法,其主要缺点是长期巩固期,在此期间可能会发生多种并发症。既往研究已经提出了几种缩短巩固期的方法。本研究中个,我们评估了体外冲击波治疗(ESWT)对下颌骨DO期间骨矿化和细胞外骨基质蛋白的影响。

27只大鼠接受下颌DO(潜伏期,3天;牵引期,10天; 0.5mm /天),根据ESWT应用的时间分为3组:I组(对照组)未接受治疗,而组II和III分别在主动牵引期之前和之后接受ESWT(0.18mJ/mm 2)。在巩固4周后收集牵开的下颌骨并通过放射学,组织学免疫组织化学分析。

结果显示,III组骨的矿物质密度明显增加,骨形成增多,胶原定向指数和更高的I型胶原蛋白和骨钙蛋白的表达更高。

综上所述,该研究结果表明,ESWT在主动牵引后的应用可增强骨骼成熟和矿化。

原始出处:


Ginini JG, Emodi O, et al., Effects of Timing of Extracorporeal Shock Wave Therapy on Mandibular Distraction Osteogenesis: An Experimental Study in a Rat Model. J Oral Maxillofac Surg. 2018 Jul 24. pii: S0278-2391(18)30838-3. doi: 10.1016/j.joms.2018.07.018. 

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    2018-12-20 xlysu
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1924422, encodeId=63f119244223e, content=<a href='/topic/show?id=542f6e8439e' target=_blank style='color:#2F92EE;'>#牵张成骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67843, encryptionId=542f6e8439e, topicName=牵张成骨)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Fri Apr 12 22:09:00 CST 2019, time=2019-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1771374, encodeId=f0a41e713744f, content=<a href='/topic/show?id=27b126533f1' target=_blank style='color:#2F92EE;'>#体外冲击波#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26533, encryptionId=27b126533f1, topicName=体外冲击波)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bad938265985, createdName=般若傻瓜, createdTime=Fri Apr 12 09:09:00 CST 2019, time=2019-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1699740, encodeId=67fe1699e4080, content=<a href='/topic/show?id=dd152024130' target=_blank style='color:#2F92EE;'>#下颌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20241, encryptionId=dd152024130, topicName=下颌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1c4f29973299, createdName=xlysu, createdTime=Thu Dec 20 00:09:00 CST 2018, time=2018-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1956718, encodeId=fbb21956e1874, content=<a href='/topic/show?id=7647e210ac' target=_blank style='color:#2F92EE;'>#FAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7210, encryptionId=7647e210ac, topicName=FAC)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Tue Sep 18 05:09:00 CST 2018, time=2018-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020460, encodeId=420520204607f, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Tue Oct 23 04:09:00 CST 2018, time=2018-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1351793, encodeId=08f51351e9348, content=<a href='/topic/show?id=e95954093cd' target=_blank style='color:#2F92EE;'>#成骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54093, encryptionId=e95954093cd, topicName=成骨)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Aug 22 11:09:00 CST 2018, time=2018-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419639, encodeId=6dfb14196398b, content=<a href='/topic/show?id=e2dc2025888' target=_blank style='color:#2F92EE;'>#下颌骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20258, encryptionId=e2dc2025888, topicName=下颌骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d9f63514434, createdName=珙桐, createdTime=Wed Aug 22 11:09:00 CST 2018, time=2018-08-22, status=1, ipAttribution=)]
    2018-10-23 小几洁
  6. [GetPortalCommentsPageByObjectIdResponse(id=1924422, encodeId=63f119244223e, content=<a href='/topic/show?id=542f6e8439e' target=_blank style='color:#2F92EE;'>#牵张成骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67843, encryptionId=542f6e8439e, topicName=牵张成骨)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Fri Apr 12 22:09:00 CST 2019, time=2019-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1771374, encodeId=f0a41e713744f, content=<a href='/topic/show?id=27b126533f1' target=_blank style='color:#2F92EE;'>#体外冲击波#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26533, encryptionId=27b126533f1, topicName=体外冲击波)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bad938265985, createdName=般若傻瓜, createdTime=Fri Apr 12 09:09:00 CST 2019, time=2019-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1699740, encodeId=67fe1699e4080, content=<a href='/topic/show?id=dd152024130' target=_blank style='color:#2F92EE;'>#下颌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20241, encryptionId=dd152024130, topicName=下颌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1c4f29973299, createdName=xlysu, createdTime=Thu Dec 20 00:09:00 CST 2018, time=2018-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1956718, encodeId=fbb21956e1874, content=<a href='/topic/show?id=7647e210ac' target=_blank style='color:#2F92EE;'>#FAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7210, encryptionId=7647e210ac, topicName=FAC)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Tue Sep 18 05:09:00 CST 2018, time=2018-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020460, encodeId=420520204607f, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Tue Oct 23 04:09:00 CST 2018, time=2018-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1351793, encodeId=08f51351e9348, content=<a href='/topic/show?id=e95954093cd' target=_blank style='color:#2F92EE;'>#成骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54093, encryptionId=e95954093cd, topicName=成骨)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Aug 22 11:09:00 CST 2018, time=2018-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419639, encodeId=6dfb14196398b, content=<a href='/topic/show?id=e2dc2025888' target=_blank style='color:#2F92EE;'>#下颌骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20258, encryptionId=e2dc2025888, topicName=下颌骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d9f63514434, createdName=珙桐, createdTime=Wed Aug 22 11:09:00 CST 2018, time=2018-08-22, status=1, ipAttribution=)]
    2018-08-22 zhaojie88
  7. [GetPortalCommentsPageByObjectIdResponse(id=1924422, encodeId=63f119244223e, content=<a href='/topic/show?id=542f6e8439e' target=_blank style='color:#2F92EE;'>#牵张成骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67843, encryptionId=542f6e8439e, topicName=牵张成骨)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Fri Apr 12 22:09:00 CST 2019, time=2019-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1771374, encodeId=f0a41e713744f, content=<a href='/topic/show?id=27b126533f1' target=_blank style='color:#2F92EE;'>#体外冲击波#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26533, encryptionId=27b126533f1, topicName=体外冲击波)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bad938265985, createdName=般若傻瓜, createdTime=Fri Apr 12 09:09:00 CST 2019, time=2019-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1699740, encodeId=67fe1699e4080, content=<a href='/topic/show?id=dd152024130' target=_blank style='color:#2F92EE;'>#下颌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20241, encryptionId=dd152024130, topicName=下颌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1c4f29973299, createdName=xlysu, createdTime=Thu Dec 20 00:09:00 CST 2018, time=2018-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1956718, encodeId=fbb21956e1874, content=<a href='/topic/show?id=7647e210ac' target=_blank style='color:#2F92EE;'>#FAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7210, encryptionId=7647e210ac, topicName=FAC)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Tue Sep 18 05:09:00 CST 2018, time=2018-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020460, encodeId=420520204607f, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Tue Oct 23 04:09:00 CST 2018, time=2018-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1351793, encodeId=08f51351e9348, content=<a href='/topic/show?id=e95954093cd' target=_blank style='color:#2F92EE;'>#成骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54093, encryptionId=e95954093cd, topicName=成骨)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Aug 22 11:09:00 CST 2018, time=2018-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419639, encodeId=6dfb14196398b, content=<a href='/topic/show?id=e2dc2025888' target=_blank style='color:#2F92EE;'>#下颌骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20258, encryptionId=e2dc2025888, topicName=下颌骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d9f63514434, createdName=珙桐, createdTime=Wed Aug 22 11:09:00 CST 2018, time=2018-08-22, status=1, ipAttribution=)]
    2018-08-22 珙桐
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