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中国胃肠间质瘤诊断治疗专家共识(2011版)

2012-04-11 张辉摘编 医学论坛网

  中国抗癌协会临床肿瘤学协作专业委员会(CSCO)胃肠间质瘤(GIST)专家委员会制定了中国胃肠间质瘤诊断治疗专家共识(2011年版)。该专家共识发表在2012年第3期《中华胃肠外科杂志》[2012,15(3):301]。   该共识是基于2009年版问世的,其更新内容主要包括:   1) 病理诊断部分更强调了基因检测,推荐对所有复发转移性GIST应进行基因突变分析。   2)&

  中国抗癌协会临床肿瘤学协作专业委员会(CSCO)胃肠间质瘤(GIST)专家委员会制定了中国胃肠间质瘤诊断治疗专家共识(2011年版)。该专家共识发表在2012年第3期《中华胃肠外科杂志》[2012,15(3):301]。   该共识是基于2009年版问世的,其更新内容主要包括:   1) 病理诊断部分更强调了基因检测,推荐对所有复发转移性GIST应进行基因突变分析。   2) 重申了对于肿瘤最大径<2cm的可以局限性GIST和有症状者应进行手术,<2cm的肿瘤可不必急于手术,手术原则中提出如果首次手术仅为R1切除,预计再次手术难度低并且可控制风险,不会造成主要功能脏器的损伤,可以考虑二次手术。   3) GIST起源于黏膜下,生长方式多样,内镜治疗不常规推荐。   4) 重新明确了分子靶向治疗为 “术前治疗”,代替了以往的“新辅助治疗”,而且包括了首次手术及日后反复手术的术前用药。明确了两项用药指征,即肿瘤体积巨大(>10cm)、术中易出血、破裂和可能造成医源性播散者;肿瘤虽可切除,但估计手术风险较大,术后复发率和死亡率高者。   

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    2012-05-20 myscience

    thanks!

    0

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