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Diabetes Care:2型糖尿病与骨折风险

2020-11-06 MedSci原创 MedSci原创

该研究的结果没有表明诊断2型糖尿病后发生骨折的风险更高。在诊断出2型糖尿病后,应鼓励患者进行积极的生活方式改变,包括进行负重体育锻炼,以改善骨骼健康。

近日,糖尿病领域权威杂志Diabetes Care上发表了一篇研究文章,研究人员旨在评估新发2型糖尿病的男性和女性与没有糖尿病的个体相比的骨折风险。

在这项队列研究中,研究人员使用了来自“健康改善网络”的常规英国初级保健数据。在2004年至2013年之间被诊断患有2型糖尿病的成年人(> 35岁)中,研究人员随访至2019年的骨折情况,并将其与没有糖尿病的个体的骨折情况进行了比较。多变量模型估计了糖尿病后首次骨折的时间。年患病率纳入者在给定年份中至少发生一次骨折。

174244名2型糖尿病患者和747290名非糖尿病患者中,男性糖尿病患者骨折风险没有增加(风险比[aHR]为0.97 [95%CI为0.94,1.00]),女性患者的骨折风险有所降低( aHR为0.94 [95%CI为0.92,0.96]。在≥85岁的人群中,糖尿病人群发生骨折的风险显著降低(男性:aHR为0.85 [95%CI 0.71,1.00];女性:aHR为0.85 [95%CI为0.78,0.94])。对于最贫困地区的男性,aHR为0.90(95%CI为0.83,0.98),女性为0.91(95%CI为0.85,0.97)。患有和不患有2型糖尿病的个体按性别划分的年骨折患病率相似。

由此可见,该研究的结果没有表明诊断2型糖尿病后发生骨折的风险更高。在诊断出2型糖尿病后,应鼓励患者进行积极的生活方式改变,包括进行负重体育锻炼,以改善骨骼健康。
 
原始出处:
 
Gabrielle S. Davie,et al.Incident Type 2 Diabetes and Risk of Fracture: A Comparative Cohort Analysis Using U.K. Primary Care Records.Diabetes care.2020.https://doi.org/10.2337/dc20-1220

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    2021-01-24 一直特立独行的猪

    学习

    0

  5. 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    2020-12-06 2636925255

    预防糖尿病

    0

  6. 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  7. 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createdBy=29392048316, createdName=ms2000001051330459, createdTime=Fri Nov 06 23:03:39 CST 2020, time=2020-11-06, status=1, ipAttribution=)]
    2020-11-07 misszhang

    谢谢MedSci提供最新的资讯

    0

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    2020-11-06 ms2000001971593954

    循证医学打开了标准治疗的大门

    0

  9. 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createdBy=148f5392162, createdName=ms2000001971593954, createdTime=Fri Nov 06 23:49:32 CST 2020, time=2020-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=897451, encodeId=9f3289e45193, content=🌹, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=36b45432299, createdName=ms6000000915264790, createdTime=Fri Nov 06 23:32:46 CST 2020, time=2020-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=897440, encodeId=c2d989e4403a, content=学习了,涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, 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    2020-11-06 ms6000000915264790

    🌹

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  10. 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    2020-11-06 ms2000001051330459

    学习了,涨知识了!

    0

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