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Thyroid:非传染性葡萄膜炎与甲状腺功能障碍的关系

2019-07-17 xing.T MedSci原创

由此可见,葡萄膜炎患者和对照者甲状腺功能异常的患病率相似,本研究结果表明非感染性葡萄膜炎与甲状腺功能紊乱无关,提示非传染性葡萄膜炎患者不需要进行常规甲状腺功能评估。

有研究表明葡萄膜炎与甲状腺疾病或功能障碍之间存在关联。然而,没有研究调查葡萄膜炎和甲状腺功能障碍之间的关联。近日,甲状腺疾病领域权威杂志Thyroid上发表了一篇研究文章,这项研究的目的是比较有和没有非传染性葡萄膜炎的患者甲状腺功能障碍的患病率。

这是一项回顾性病例对照研究,共纳入了255例非感染性葡萄膜炎患者(葡萄膜炎组)和600例对照者(对照组),其中492例(58.9%)为女性。葡萄膜炎患者组和对照组之间在基线特征方面没有差异,包括年龄、性别和糖尿病高血压和心脏病等全身性疾病患病情况。

风湿性疾病和肠道疾病在葡萄膜炎组中更常见(分别为p<0.001和p=0.007)。总体而言,61例(7.3%)患者出现甲状腺功能紊乱,其中55例甲状腺功能减退,6例甲状腺功能亢进。235例葡萄膜炎患者中有17例(7.2%)和600例对照者中有44例(7.3%)被诊断为甲状腺功能障碍,两组的比例相似(p=0.96)。其中,所有葡萄膜炎患者和对照组中38名(86.4%)患者被诊断为甲状腺功能减退症(p=0.63)。与没有甲状腺功能障碍的葡萄膜炎患者相比,患有甲状腺功能障碍的葡萄膜炎患者中女性比例更高(p=0.002)。最常见的葡萄膜炎类型是前葡萄膜炎。在有或没有甲状腺功能障碍诊断的患者中,葡萄膜炎类型没有显著差异。

由此可见,葡萄膜炎患者和对照者甲状腺功能异常的患病率相似,本研究结果表明非感染性葡萄膜炎与甲状腺功能紊乱无关,提示非传染性葡萄膜炎患者不需要进行常规甲状腺功能评估。

原始出处:

Amir Rosenblatt,etal.Association Between Non-Infectious Uveitis and Thyroid Dysfunction: A Case Control Study.Thyroid.2019.https://www.liebertpub.com/doi/10.1089/thy.2016.0598

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    2019-12-23 xzw113
  2. [GetPortalCommentsPageByObjectIdResponse(id=1911502, encodeId=efa2191150236, content=<a href='/topic/show?id=77b3259009f' target=_blank style='color:#2F92EE;'>#传染性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25900, encryptionId=77b3259009f, topicName=传染性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2317301, createdName=xzw113, createdTime=Mon Dec 23 07:29:00 CST 2019, time=2019-12-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=369976, encodeId=483a3699e62f, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2018/12/05/9151d1e89e73add788e7d96c55fb5dec.jpg, createdBy=dcfd2497546, createdName=124902dfm95暂无昵称, createdTime=Sat Jul 20 07:23:31 CST 2019, time=2019-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421246, encodeId=5467142124684, content=<a href='/topic/show?id=09d33294eb8' target=_blank style='color:#2F92EE;'>#功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32947, encryptionId=09d33294eb8, topicName=功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3493649807, createdName=naiwu78, createdTime=Thu Jul 18 22:29:00 CST 2019, time=2019-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=369815, encodeId=84cc36981526, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1bb241978, createdName=phoebeyan520, createdTime=Wed Jul 17 10:23:44 CST 2019, time=2019-07-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=369811, encodeId=5a0f369811c4, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Wed Jul 17 08:48:48 CST 2019, time=2019-07-17, status=1, ipAttribution=)]
    2019-07-20 124902dfm95暂无昵称

    学习了,谢谢分享

    0

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    2019-07-17 phoebeyan520

    学习了

    0

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    2019-07-17 龙胆草

    学习谢谢分享

    0

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