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Crit Care:SAPS II和SAPS3死亡评分校准的决定因素有哪些?

2017-04-04 xing.T MedSci原创

由此可见,这两个评分均高估了当前欧洲ICU患者的死亡率。对SAPS II和SAPS 3评分的校准失误大小不仅取决于病人的特点,而且还取决于中心的特点。此外,校准中许多中心间变异性仍然无法通过这些因素予以解释。

简化急性生理学评分(SAPS)II和SAPS3的主要目标是预测住进重症监护病房(ICU)患者的死亡率。以前的研究表明这些评分的校准可能会因国家、中心和/或患者特点的不同而有所不同。近日,危重病医学领域权威杂志Critical Care上发表了一篇研究文章,研究人员旨在评估这些评分校准的决定因素。

研究人员对17个欧洲国家的120个中心的5266例住进ICU为期4周内的患者中评估了SAPS II和SAPS3评分的校准。研究人员得到了校准曲线、布莱尔评分、标准化死亡率。对归因于SAP项目的点进行重新评估,并与原始分数进行比较。最后,研究人员验证了校准和中心特点之间的相关性。

研究人员发现两个评分均高估了死亡率:SAPS II评分的标准化死亡率为0.75(95%可信区间为0.71-0.79),SAPS3评分为0.91(95%可信区间为0.86-0.96)。这种过高的估计可以由评分的一些项目与死亡率之间相关性的改变,尤其是心率、格拉斯哥昏迷量表评分和SAPS II的艾滋病诊断,部分来解释。在低健康支出的国家,这两个分数的校准相对较好。校准曲线中的中心间变异性远远大于预期。

由此可见,这两个评分均高估了当前欧洲ICU患者的死亡率。对SAPS II和SAPS 3评分的校准失误大小不仅取决于病人的特点,而且还取决于中心的特点。此外,校准中许多中心间变异性仍然无法通过这些因素予以解释。

原始出处:

Antoine Poncet, et al. Determinants of the calibration of SAPS II and SAPS 3 mortality scores in intensive care: a European multicenter study.Critical Care.2017. http://ccforum.biomedcentral.com/articles/10.1186/s13054-017-1673-6

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    2017-05-29 jiyangfei
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    2017-04-13 zz70
  4. 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content=学习啦 讲的非常好 非常棒, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eo2GMhevabZrvYIDhcYQOadp8uNxP2luzicRh5E0OHqMU9kYxib3dV5Qsd9UASTrkcc9ibiaN90Zwo1Tw/132, createdBy=275f1684782, createdName=wang_shengli, createdTime=Tue Apr 04 19:16:32 CST 2017, time=2017-04-04, status=1, ipAttribution=)]
    2017-04-05 szc1181881761

    学习了,让人耳目一新

    0

  6. 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content=学习啦 讲的非常好 非常棒, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eo2GMhevabZrvYIDhcYQOadp8uNxP2luzicRh5E0OHqMU9kYxib3dV5Qsd9UASTrkcc9ibiaN90Zwo1Tw/132, createdBy=275f1684782, createdName=wang_shengli, createdTime=Tue Apr 04 19:16:32 CST 2017, time=2017-04-04, status=1, ipAttribution=)]
    2017-04-05 飛歌

    学习了很有用

    0

  7. 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content=学习啦 讲的非常好 非常棒, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eo2GMhevabZrvYIDhcYQOadp8uNxP2luzicRh5E0OHqMU9kYxib3dV5Qsd9UASTrkcc9ibiaN90Zwo1Tw/132, createdBy=275f1684782, createdName=wang_shengli, createdTime=Tue Apr 04 19:16:32 CST 2017, time=2017-04-04, status=1, ipAttribution=)]
    2017-04-04 cqykthl

    重症监护的常用指标

    0

  8. 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objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170207/IMG589913E36908D4741.jpg, createdBy=99331680071, createdName=knowheart, createdTime=Tue Apr 04 20:14:51 CST 2017, time=2017-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185165, encodeId=014518516583, content=好经验共同学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K0LqDY57Aia0TOQByoJhNt3icm4sfukp500hLH6RHOpFdV01NbECtAV7s0qKpQPibyRukQAwAmqJU3X/0, createdBy=f91f1928792, createdName=九九消寒, createdTime=Tue Apr 04 20:04:08 CST 2017, time=2017-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185156, encodeId=9c3c18515678, content=学习啦 讲的非常好 非常棒, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eo2GMhevabZrvYIDhcYQOadp8uNxP2luzicRh5E0OHqMU9kYxib3dV5Qsd9UASTrkcc9ibiaN90Zwo1Tw/132, createdBy=275f1684782, createdName=wang_shengli, createdTime=Tue Apr 04 19:16:32 CST 2017, time=2017-04-04, status=1, ipAttribution=)]
    2017-04-04 knowheart

    对SAPS II和SAPS 3评分的校准失误大小不仅取决于病人的特点,而且还取决于中心的特点。

    0

  9. 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objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170207/IMG589913E36908D4741.jpg, createdBy=99331680071, createdName=knowheart, createdTime=Tue Apr 04 20:14:51 CST 2017, time=2017-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185165, encodeId=014518516583, content=好经验共同学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K0LqDY57Aia0TOQByoJhNt3icm4sfukp500hLH6RHOpFdV01NbECtAV7s0qKpQPibyRukQAwAmqJU3X/0, createdBy=f91f1928792, createdName=九九消寒, createdTime=Tue Apr 04 20:04:08 CST 2017, time=2017-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=185156, encodeId=9c3c18515678, content=学习啦 讲的非常好 非常棒, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eo2GMhevabZrvYIDhcYQOadp8uNxP2luzicRh5E0OHqMU9kYxib3dV5Qsd9UASTrkcc9ibiaN90Zwo1Tw/132, createdBy=275f1684782, createdName=wang_shengli, createdTime=Tue Apr 04 19:16:32 CST 2017, time=2017-04-04, status=1, ipAttribution=)]
    2017-04-04 九九消寒

    好经验共同学习

    0

  10. 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content=学习啦 讲的非常好 非常棒, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eo2GMhevabZrvYIDhcYQOadp8uNxP2luzicRh5E0OHqMU9kYxib3dV5Qsd9UASTrkcc9ibiaN90Zwo1Tw/132, createdBy=275f1684782, createdName=wang_shengli, createdTime=Tue Apr 04 19:16:32 CST 2017, time=2017-04-04, status=1, ipAttribution=)]
    2017-04-04 wang_shengli

    学习啦 讲的非常好 非常棒

    0

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