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Lancet psychiat:精神病患者中艾滋、乙肝和丙肝的发病率研究

2017-07-05 qinqiyun MedSci原创

重度精神病会增加发病率和死亡率。在重度精神病患者中血源性病毒(BBVs)的患病风险增加。

背景:重度精神病会增加发病率和死亡率。在重度精神病患者中血源性病毒(BBVs)的患病风险增加引起关注,但这一问题尚未明确。Clarissa Bauer-Staeb及其同事致力于评估BBVs在重度精神病患者中的发病率和风险因子。方法:研究者设计了一个全国范围、基于人群、交叉研究,来评估瑞典全部18岁及以上年龄的重度精神病患者中艾滋(HIV)、乙肝(HBV)和丙肝(HCV)的发病率。纳入的精神病有精神分裂症、情感性分裂障碍、躁郁症和其他精神病。应用多变量的逻辑回归来确定重度精神病患者与正常人群的BBVs的优势比(odds),并验证BBV感染的独立风险因子(年龄、性别、免疫状况、社会地位、教育和药物滥用)。结果:瑞典的6 815 931人中有97 797人(1.43%)被诊断重度精神病,评估这些人群中BBVs的发病率,其中230人(0.24%)患有HIV、518人(0.53%)患有HBV、4476(4.58%)患有HCV。通过统计社会人口特征,与正常人群相比,HIV、HBV和HCV在重度精神病患者人群中的发病率均更高,优势比分别是2.57(95% CI 2.25–2.94, p<0.0

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    2017-07-08 howi
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    2017-07-07 1e10c84am36(暂无匿称)

    文章很好,拜读了

    0

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