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Stroke:气道正压通气在急性卒中患者睡眠呼吸暂停检测中的准确性

2019-10-24 xing.T MedSci原创

由此可见,鉴于卒中急性期的睡眠呼吸暂停频率很高,并且在这种情况下进行完整的多导睡眠监测研究的复杂性,PAP设备的诊断模式可作为急性卒中患者睡眠呼吸暂停检测的替代工具。

睡眠呼吸暂停与急性卒中患者的不良预后有关。多导睡眠图是睡眠呼吸暂停诊断的金标准,但在急性卒中情况下作为常规方法并不可行。当前一代的气道正压(PAP)设备可以检测不同类型的呼吸事件。近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,这项研究旨在比较急性卒中患者PAP装置中使用的算法与多导睡眠图上手动评分事件。

在急性卒中发作后的前48小时内,研究人员同时使用标准多导睡眠图和PAP装置进行一项睡眠研究,对29例急性卒中患者(59.5±12.1岁)进行了前瞻性评估。

通过PAP装置,每个呼吸暂停-呼吸不足指数值的受试者工作特性曲线下面积均大于0.90。呼吸暂停低通气指数(rs=0.92; P<0.001)、呼吸不足指数(rs=0.89; p<0.001)和呼吸暂停指数(rs=0.70; P<0.001)与装置检测到的事件和多导睡眠图上手动评分事件之间存在良好的相关性。

由此可见,鉴于卒中急性期的睡眠呼吸暂停频率很高,并且在这种情况下进行完整的多导睡眠监测研究的复杂性,PAP设备的诊断模式可作为急性卒中患者睡眠呼吸暂停检测的替代工具。 

原始出处:

Millene Rodrigues Camilo.et al.Diagnostic Accuracy of Positive Airway Pressure Device for Sleep Apnea Detection in Acute Stroke Patients.stroke.2019.https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.027141

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  7. [GetPortalCommentsPageByObjectIdResponse(id=2070299, encodeId=6b0120e029936, content=<a href='/topic/show?id=9a27631888f' target=_blank style='color:#2F92EE;'>#正压通气#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63188, encryptionId=9a27631888f, topicName=正压通气)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=afa4194, createdName=cenghis, createdTime=Fri Jun 12 18:52:00 CST 2020, time=2020-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1905969, encodeId=224e190596916, content=<a href='/topic/show?id=34953120e52' target=_blank style='color:#2F92EE;'>#准确性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31207, encryptionId=34953120e52, topicName=准确性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=512a199, createdName=lilianxiang, createdTime=Fri Jan 17 14:52:00 CST 2020, time=2020-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989136, encodeId=d7e1198913635, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Tue Sep 15 22:52:00 CST 2020, time=2020-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720312, encodeId=85291e20312c0, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Sat Apr 18 21:52:00 CST 2020, time=2020-04-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1284461, encodeId=08f2128446167, content=<a href='/topic/show?id=d2155222281' target=_blank style='color:#2F92EE;'>#急性卒中#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52222, encryptionId=d2155222281, topicName=急性卒中)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=afa4194, createdName=cenghis, createdTime=Sat Oct 26 11:52:00 CST 2019, time=2019-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596580, encodeId=d5451596580af, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Sat Oct 26 11:52:00 CST 2019, time=2019-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026482, encodeId=a5b31026482f5, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Oct 24 23:52:00 CST 2019, time=2019-10-24, status=1, ipAttribution=)]
    2019-10-24 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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JAMA:成人睡眠呼吸暂停患者气道正压通气与心血管事件和死亡的关系

对于睡眠呼吸暂停患者,进行正压通气不能降低患者心血管事件发生率以及死亡风险。尽管正压通气有助于睡眠呼吸暂停症状的缓解,但其不能改变睡眠呼吸暂停患者心脏风险高的事实。

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