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澳大利亚研究人员在花生过敏方面取得了突破

2017-08-17 MedSci MedSci原创

澳大利亚的研究人员报道了一项重大突破,他们发现了一种长期治疗方法,在不久的将来有望治愈致命的花生过敏症。在墨尔本的默多克儿童研究所(Murdoch children Research Institute)的科学家们进行的临床试验中,花生过敏的儿童在18个月的时间里服用了少量的花生蛋白。当实验在2013年结束时,大约80%的孩子能够忍受花生。周三发表在医学杂志《柳叶刀》上的这项研究发现,在随后四年的


澳大利亚的研究人员报道了一项重大突破,他们发现了一种长期治疗方法,在不久的将来有望治愈致命的花生过敏症。

在墨尔本的默多克儿童研究所(Murdoch children Research Institute)的科学家们进行的临床试验中,花生过敏的儿童在18个月的时间里服用了少量的花生蛋白。

当实验在2013年结束时,大约80%的孩子能够忍受花生。

周三发表在医学杂志《柳叶刀》上的这项研究发现,在随后四年的时间里,大约70%的人仍然可以吃花生而不产生不良反应。

研究负责人Mimi Tang说:"这一发现的重要性在于,这些孩子能够吃花生,就像没有花生过敏的孩子一样,而且他们仍然保持着对花生的耐受状态。"

"这些发现表明,在完成治疗后的4年里,我们的治疗在诱导长期耐受性方面是安全有效的。"

"这也表明,耐受性是治疗食物过敏的现实目标。"

20个孩子中有1个,大约100个成年人中有2个对食物过敏,其中有海鲜、牛奶、鸡蛋和花生,这些都是最典型的诱因。

花生是引起过敏反应最常见的食物之一,可引起致命的过敏反应。

研究人员表示,默多克的研究提供了"迄今为止最有力的证据,证明对花生过敏是有可能治愈的"。

Tang说:"这是解决西方国家食品过敏问题的一个有效措施。"

十岁的Olivia May在七年前吃花生酱三明治时出现了过敏反应。Olivia的母亲塔尼娅告诉澳大利亚广播公司说:"我们第一次去看了过敏科医生,他说'对不起,你必须回家,清空你的储藏室,清除所有的坚果。'"

但在参加试验后,Olivia不再受过敏的影响。

Tanya May说:"我想,也许最好的事情之一就是能去参加派对,我可以放心的让她去,或者在睡觉前休息一下。"

"我过去常常把EpiPen(肾上腺素注射器)交给一个我几乎不认识的父母,给他们一个三十秒的解释如何使用它。"

"(但)不必担心把责任放在别人的手里是一种巨大的解脱。"

56名儿童参与完成了这项研究,其中一半人接受了安慰剂,一半的人接受了治疗,治疗组的免疫系统对过敏产生了耐受性。

研究人员现在正试图通过一项更大的研究来证实这一结果,他们说"对现代食物过敏的盛行有重要的影响"。


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    学习了谢谢分享

    0

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    2017-08-18 杨利洪

    学习了分享了

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    2017-08-17 中医痴

    不错的,学习了,谢谢分享!

    0

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