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专家呼吁建立精准医学发展共享机制

2016-06-21 李晨阳 中国科学报

6月16日~17日,以“精准医学与肿瘤治疗”为主题的首届雁栖湖医学高峰论坛在京召开。会上,中国工程院院士、北大医学部主任詹启敏指出,发展精准医学需要建立医院间的共享机制,破除各单位“各立门派”、互不往来的弊端。 詹启敏介绍说,精准医学的一大重要支撑平台是“大数据平台”。通过聚集海量的队列数据、临床数据、组学数据、结构生物学数据、药物分子信息,再经由生物信息技术处理,才能发现新靶点、新结构,

6月16日~17日,以“精准医学与肿瘤治疗”为主题的首届雁栖湖医学高峰论坛在京召开。会上,中国工程院院士、北大医学部主任詹启敏指出,发展精准医学需要建立医院间的共享机制,破除各单位“各立门派”、互不往来的弊端。

詹启敏介绍说,精准医学的一大重要支撑平台是“大数据平台”。通过聚集海量的队列数据、临床数据、组学数据、结构生物学数据、药物分子信息,再经由生物信息技术处理,才能发现新靶点、新结构,设计新药物、新方案,进而推进新标准和新规范的制定。

然而,信息孤岛现象阻碍了上述进程。北京大学肿瘤医院院长季加孚指出,精准医学的肿瘤研究平台需要成规模、高水平的集团协同。这种协同的前提是具备普遍约束力的规范、便于共享的环境和可靠的质量监管。相应地,现有的激励、管理制度也应随之调整。

建立和共享生物样本库,也是此次论坛热议的话题之一。詹启敏表示,生物样本不仅需要符合严格的质量要求,还必须匹配完整、真实、标准化的临床信息。然而,由于种种原因,目前我国临床信息资料的质量不容乐观,是必须迫切解决的问题之一。

此次论坛由中国科学院大学和北京市怀柔区政府主办,国科大医学院和国科大附属北京怀柔医院承办。众多两院院士及国内外专家学者参会并作学术报告。

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    2016-06-24 WEIXIN0e0dcfc0

    非常好。

    0

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    2016-06-23 chendoc248

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根据英国儿童癌症幸存者的研究分析,肾母细胞瘤的幸存者诊断后30至50年的过早死亡的风险正在大幅增加。随后的肿瘤和心脏问题解释了75%的超额死亡。伯明翰大学儿童癌症幸存者研究中心的流行病学Michael Hawkins教授和他的同事们对肾母细胞瘤诊断后50年的不良预后风险进行了研究。具体而言,研究人员评估了导致特定的死亡率、随后的原发性肿瘤的风险、不良妊娠结局的风险、健康状况、吸烟和饮酒、教育程度、

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美国一项研究表明,美国胃肠病学会(AGA)指南在胰腺囊肿检出进展期肿瘤方面的准确性欠佳,综合分子检测的替代方法更具应用前景,但仍需进一步验证。论文发表于《消化内镜》杂志6月刊[Gastrointest Endosc2016,83(6):1107]。        该研究纳入225例因胰腺囊肿接受超声内镜引导下细针穿刺抽吸(EUS-FNA)检查的患者

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