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Ann Rheum Dis:痛风患者的工作失能:基于人群的病例对照研究

2017-11-26 xiangting MedSci原创

http://ard.bmj.com/content/early/2017/11/23/annrheumdis-2017-212063

这项研究旨在探讨与匹配的人群对照相比,痛风患者工作失能的程度和成本,并分析工作失能的预测因素。

利用2000年1月至2012年12月瑞典国家和地区登记的资料,纳入2003-2009年首次诊断为痛风的4571例工作年龄的患者,和22482例人群对照,根据年龄、性别和居住地进行匹配。计算基线特征(教育水平,收入,以前就业和合并症)与诊断3年后因病假和伤残抚恤金而造成的旷工天数(缺勤)的差异。通过条件性logistic回归确定亚组中新发旷工(>90天/年)的预测因子。

与对照组相比,痛风患者(中位年龄53岁)合并症明显较多,收入较低,受教育程度较低。痛风患者3年随访期间的平均缺勤率高于对照组,分别为22%和14%(P <0.0001)。多因素分析中新发旷工可由痛风预测(OR 1.47; 95%CI 1.23至1.75)。与新发旷工独立相关的其他变量包括教育年限≤12年,既往失业和病假史,以及几种合并症(肾病、心血管疾病、酗酒和肥胖)。

在调整相关合并症和社会经济差异之后,痛风与劳动力丧失导致的高缺勤率和高社会成本相关。强化痛风治疗是否具有成本效益仍需要进一步的研究。

原始出处:
Valgerdur Sigurdardottir, et al. Work disability in gout: a population-based case-control study. Ann Rheum Dis. 23 November 2017. 

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    2018-01-08 amyloid
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    2018-08-21 xugc
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    2017-11-26 惠映实验室

    学习了.谢谢.

    0

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