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Clin Obesity:逆转常规认知!仅仅肥胖或并不会增加个体的死亡风险!

2018-07-19 佚名 细胞

日前,一项刊登在国际杂志Clinical Obesity上的研究报告中,来自约克大学的科学家们通过研究发现,代谢健康肥胖且并无其它代谢风险因素的患者或许死亡率/风险并不会增加;本文研究结果能够影响我们对肥胖和健康之间关联的理解。

日前,一项刊登在国际杂志Clinical Obesity上的研究报告中,来自约克大学的科学家们通过研究发现,代谢健康肥胖且并无其它代谢风险因素的患者或许死亡率/风险并不会增加;本文研究结果能够影响我们对肥胖和健康之间关联的理解。

研究者Jennifer Kuk教授说道,我们的研究发现与大多数文献报道结果相反,因为大部分研究都将代谢健康肥胖(metabolic healthy obesity)定义为存在一种代谢风险因素,这显然是有问题的,高血压本身就会增加个体死亡的风险,而过去的文献将这些患者称之为肥胖和高血压患者;这就是为何大部分研究都发现,健康肥胖状态仍然与较高的死亡风险相关的原因了。

研究者表示,与血脂异常、高血压或糖尿病本身不同,这些因素与个体较高的死亡风险相关,然而对于单一的肥胖而言或许并非如此。文章中,研究人员对来自5项队列研究中的54089名男性和女性进行研究,研究者将参与者归类为单独肥胖或与一种代谢因子聚集组,单独血糖、血压或血脂升高或与肥胖或其它代谢因素聚集组,研究人员将每组研究对象与正常体重且没有任何代谢风险因子的人群进行对比来观察每一组研究对象中有多少人会发生死亡。

当前的体重管理指南认为,BMI超过30kg/平方米的个体就应该减肥了,这就提示,如果你患有肥胖,甚至不携带其它风险因子的话,那么你都是不健康的人群,研究者发现,每20名肥胖个体中就有1人不存在其它机体的代谢异常。

最后研究者Kuk表示,我们发现,代谢健康肥胖的个体实际上死亡风险并不会增加,正常体重且没有其它任何代谢风险因素的人群与肥胖且没有其它风险因素的人群的死亡可能性是一样的,这也就意味着,当能够获得一定健康益处时,仅表现为代谢健康肥胖的成千上万名北美人群才会被告知让他们减肥。

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    2019-02-28 zhanglin3079
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    2018-07-21 lingaifan
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    2018-07-21 skhzy

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