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Circulation:Ross手术可替代机械主动脉瓣置换术(AVR)

2016-08-23 fsy 译 MedSci原创

在年轻人和中年人中,理想的主动脉瓣替代疗法仍然不明。研究人员试图比较接受Ross手术和接受机械主动脉瓣置换术(AVR)患者的长期结果。从1990年到2014年,在一个单一机构中,258例患者接受了Ross手术,1444例患者接受了机械AVR。研究人员通过使用倾向得分将患者匹配分成208对。这些患者的平均年龄为37.2±10.2岁,63%为男性。平均随访时间为14.2±6.5年。虽然Ross组的无心

在年轻人和中年人中,理想的主动脉瓣替代疗法仍然不明。研究人员试图比较接受Ross手术和接受机械主动脉瓣置换术(AVR)患者的长期结果。

从1990年到2014年,在一个单一机构中,258例患者接受了Ross手术,1444例患者接受了机械AVR。研究人员通过使用倾向得分将患者匹配分成208对。这些患者的平均年龄为37.2±10.2岁,63%为男性。平均随访时间为14.2±6.5年。

虽然Ross组的无心脏和瓣膜相关的死亡率明显改善(Ross vs AVR:危险比,0.22;95%置信区间,0.034-0.86;P=0.03),但两组患者的总生存率是一样的(Ross vs AVR:危险比0.91,95%置信区间,0.38-2.16; P=0.83)。两组患者经过手术后无再次干预的概率也是一样的(Ross vs AVR:危险比,1.86; 95%置信区间,0.76-4.94; P=0.18)。 Ross组患者手术后无卒中或大出血的长期结果要优于AVR组(Ross vs AVR:危险比, 0.09;95%置信区间,0.02-0.31; P<0.001)。

在Ross手术组和机械AVR组之间,长期的生存和无再次干预治疗的结果是一样的。然而,Ross手术组的无心脏和瓣膜相关死亡都有所改善,并且卒中和大出血的发生率都显著减少。在专业的治疗中心中,Ross手术是一个很好的选择,所以接受AVR的年轻人和中年人可以考虑接受Ross手术。

原始出处:

Amine Mazine, Tirone E. David, Vivek Rao,et al.Long-Term Outcomes of the Ross Procedure Versus Mechanical Aortic Valve Replacement,Circulation,2016.8.23

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    2017-05-27 yxch48
  3. 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    2016-10-11 1e0ece0dm09(暂无匿称)

    在学习了

    0

  4. 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content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Aug 25 19:08:00 CST 2016, time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=103817, encodeId=970d10381ed1, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Aug 25 19:08:00 CST 2016, time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=103572, encodeId=05a21035e210, content=谢谢,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Thu Aug 25 15:04:00 CST 2016, time=2016-08-25, status=1, ipAttribution=)]
    2016-09-25 1e10c84am36(暂无匿称)

    文章很好值得关注

    0

  5. 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channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat Sep 03 06:35:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=106206, encodeId=627d106206a2, content=很好的文章,读一读有好处。, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Sun Aug 28 10:44:00 CST 2016, time=2016-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=103816, encodeId=a3e41038167f, 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  6. 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time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=103572, encodeId=05a21035e210, content=谢谢,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Thu Aug 25 15:04:00 CST 2016, time=2016-08-25, status=1, ipAttribution=)]
    2016-09-03 jyzxjiangqin

    越来越先进发达。

    0

  7. 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channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat Sep 03 06:35:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=106206, encodeId=627d106206a2, content=很好的文章,读一读有好处。, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Sun Aug 28 10:44:00 CST 2016, time=2016-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=103816, encodeId=a3e41038167f, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Aug 25 19:08:00 CST 2016, time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=103817, encodeId=970d10381ed1, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Aug 25 19:08:00 CST 2016, time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=103572, encodeId=05a21035e210, content=谢谢,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Thu Aug 25 15:04:00 CST 2016, time=2016-08-25, status=1, ipAttribution=)]
    2016-08-28 李东泽

    很好的文章,读一读有好处。

    0

  8. 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channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat Sep 03 06:35:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=106206, encodeId=627d106206a2, content=很好的文章,读一读有好处。, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Sun Aug 28 10:44:00 CST 2016, time=2016-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=103816, encodeId=a3e41038167f, 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time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=103572, encodeId=05a21035e210, content=谢谢,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Thu Aug 25 15:04:00 CST 2016, time=2016-08-25, status=1, ipAttribution=)]
    2016-08-25 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!

    0

  9. 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time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=103572, encodeId=05a21035e210, content=谢谢,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Thu Aug 25 15:04:00 CST 2016, time=2016-08-25, status=1, ipAttribution=)]
    2016-08-25 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!

    0

  10. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 25 08:58:00 CST 2016, time=2016-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661508, encodeId=d3d1166150835, content=<a href='/topic/show?id=773c156450f' target=_blank style='color:#2F92EE;'>#Ross手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15645, encryptionId=773c156450f, topicName=Ross手术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=845b25305115, createdName=yanjie6253_56072850, createdTime=Fri Jul 07 07:53:00 CST 2017, time=2017-07-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=110064, encodeId=026711006432, content=越来越先进发达。, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sat Sep 03 06:35:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=106206, encodeId=627d106206a2, content=很好的文章,读一读有好处。, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Sun Aug 28 10:44:00 CST 2016, time=2016-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=103816, encodeId=a3e41038167f, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Aug 25 19:08:00 CST 2016, time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=103817, encodeId=970d10381ed1, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Aug 25 19:08:00 CST 2016, time=2016-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=103572, encodeId=05a21035e210, content=谢谢,学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Thu Aug 25 15:04:00 CST 2016, time=2016-08-25, status=1, ipAttribution=)]
    2016-08-25 刘煜

    谢谢,学习了。

    0

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