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严密监控H7N9甲型流感病毒很重要

2013-07-10 舒跃龙等 《自然》

大量生物特征表明,H7N9甲型流感病毒对人类已构成重大威胁。本周《自然》杂志发表了新的数据,说明对H7N9甲型流感病毒进行严密监控的重要性。 与H5N1和H1N1病毒不同,H7N9病毒能够和人类受体结合,感染人类气管和肺部,并在细胞内自我复制,哪怕是支气管最末端的细胞。舒跃龙指出,双重受体结合与高增长速度使H7N9病毒更容易从鸟类传播到人类。然而,H7N9病毒在人类气管和肺部的自我复制能

大量生物特征表明,H7N9甲型流感病毒对人类已构成重大威胁。本周《自然》杂志发表了新的数据,说明对H7N9甲型流感病毒进行严密监控的重要性。

与H5N1和H1N1病毒不同,H7N9病毒能够和人类受体结合,感染人类气管和肺部,并在细胞内自我复制,哪怕是支气管最末端的细胞。舒跃龙指出,双重受体结合与高增长速度使H7N9病毒更容易从鸟类传播到人类。然而,H7N9病毒在人类气管和肺部的自我复制能力下降,因而减低其人传人的效率。

大部分患者在感染病毒后会出现严重病征。研究还显示,受感染的患者会出现异常高的炎症和免疫细胞水平。这个俗称“细胞因子风暴”的现象,可能是导致病征加剧的真正元凶。作者指出,现在没有足够数据证明季节性流感疫苗能为我们提供有效的免疫力,虽然病毒还没有在人与人之间传播,但是情况的确令人担忧。

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