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JAMA Cardiol:美研究称,近1/3主动脉瓣膜置换术后老年患者有抑郁症状

2018-01-22 朱柳媛 中国循环杂志

近期,JAMA心脏病学子刊发表的一项研究显示,在接受经导管或外科主动脉瓣膜置换术的老年患者中,抑郁症状比较常见,且抑郁症状与死亡有关。

近期,JAMA心脏病学子刊发表的一项研究显示,在接受经导管或外科主动脉瓣膜置换术的老年患者中,抑郁症状比较常见,且抑郁症状与死亡有关。

研究者对多中心的FRAILTY-AVR前瞻性队列研究提前进行了数据分析。该研究一共纳入1035例患者,患者平均年龄81岁。

在这些患者中,近1/3(31.5%)筛查出有抑郁症状,8.6%医疗记录中有抑郁症状。

校正潜在混淆因素后,研究者发现,基线有抑郁症状的患者主动脉瓣置换术后1个月和1年时死亡的风险分别增加1.2倍和53%。持续处于抑郁状态即术后6个月后仍然有抑郁症状的患者术后1年死亡的风险增加了2倍。

研究者表示,如果抑郁症是主动脉瓣膜置换术后影响临床预后的独立危险因素,那么有针对性地转诊和治疗对于改善患者临床预后可能有益处。

相关述评专家指出,未来需要确定抑郁症治疗是否会改善主动脉瓣膜置换术后结局。

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    2018-02-24 秀红

    学习了

    0

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createdName=12498e5fm17(暂无昵称), createdTime=Wed Jan 24 12:47:00 CST 2018, time=2018-01-24, status=1, ipAttribution=)]
    2018-07-25 yxch48
  5. 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