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NEJM:低钠、高钾摄入可降低心血管事件风险

2021-11-14 Nebula MedSci原创

钠排泄量越高、钾排泄量越低和钠/钾排泄量比越高,心血管事件风险就越高

钠摄入量与血管疾病之间的相关性仍然存在争议,部分原因是对钠摄入量的评估不准确。在一段时间内,评估24小时尿钠排泄被认为是一个准确的方法。本研究旨在通过24小时尿评估钠、钾摄入量与心血管事件的相关性。

该研究纳入了来自六个一般健康成年人的前瞻性队列的个人参与者的数据;每个参与者至少收集了两次24小时尿液样本以评估钠和钾的排泄量。主要终点是心血管事件(冠脉重建、致死性/非致死性心肌梗死卒中)。

24小时尿钠排泄量与心血管事件风险的相关性

共纳入了10709位受试者,平均年龄为51.5±12.6岁,其中54.2%的为女性。中位随访了8.8年,共发生了571例心血管事件(发生率 5.9/1000人·年)。中位24小时尿钠排泄量为3270mg(10%-90%分位值:2099-4899mg)。经混杂因素校正后,分析显示,钠排泄量越高、钾排泄量越低和钠/钾排泄量比越高,受试者的心血管事件风险就越高(p≤0.005)。

24小时尿钾排泄量与心血管事件风险的相关性

尿钠排泄量、钾排泄量和钠/钾排泄量比的最高四分位个体与最低四分位个体相比时的心血管事件风险比分别是1.60(95% CI 1.19-2.14)、0.69(0.51-0.91)和1.62(1.25-2.10)。24小时尿钠排泄量每增加1000mg,心血管事件风险升高18%(风险比 1.18,95% CI 1.08-1.29),而钾排泄量每增加1000mg,心血管事件风险就会降低18%(0.82, 0.72-0.94)。

综上,通过24小时尿排泄量评估的的高钠和低钾摄入量与较高的心血管事件风险相关,而且是以剂量反应性方式。该研究结果可能支持在当前的水平基础上进一步减少钠摄入量、增加钾摄入量。

原始出处:

Ma, Yuan., He, Feng J., Sun, Qi., et al. 24-Hour Urinary Sodium and Potassium Excretion and Cardiovascular Risk. New England Journal of Medicine. November 13, 2021. https://doi.org/10.1056/NEJMoa2109794

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  2. 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createdName=ms4000001739841053, createdTime=Mon Nov 15 07:07:11 CST 2021, time=2021-11-15, status=1, ipAttribution=)]
    2022-04-03 1881eacd07m

    学习

    0

  3. 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createdName=ms4000001739841053, createdTime=Mon Nov 15 07:07:11 CST 2021, time=2021-11-15, status=1, ipAttribution=)]
    2022-01-20 ms2000000492374631

    学到了很多!#高血压#

    0

  4. 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GetPortalCommentsPageByObjectIdResponse(id=1514541, encodeId=04f415145416d, content=<a href='/topic/show?id=102f102e8375' target=_blank style='color:#2F92EE;'>#高钾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102783, encryptionId=102f102e8375, topicName=高钾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c5d010658633, createdName=ms7517674339485982, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538290, encodeId=7d37153829016, content=<a href='/topic/show?id=1258263835a' target=_blank style='color:#2F92EE;'>#低钠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26383, encryptionId=1258263835a, topicName=低钠)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9512951240, createdName=zz12341238, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070318, encodeId=fc4310e03189b, content=是极为不平静的一天。就是在这一, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Mon Nov 15 08:07:27 CST 2021, time=2021-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070311, encodeId=8fb110e0311e2, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=415c5624067, createdName=ms4000001739841053, createdTime=Mon Nov 15 07:07:11 CST 2021, time=2021-11-15, status=1, ipAttribution=)]
    2021-11-20 1591ff5c5cm

    这个应该是大家都已经接受的

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1643774, encodeId=3aef1643e74d6, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Fri Dec 17 20:47:47 CST 2021, time=2021-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1208331, encodeId=f6161208331d7, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0eb2046086, createdName=1881eacd07m, createdTime=Sun Apr 03 11:00:49 CST 2022, time=2022-04-03, status=1, ipAttribution=), 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070864, encodeId=e1d010e086445, content=学习,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a25151353, createdName=14698a10m84暂无昵称, createdTime=Tue Nov 16 19:56:53 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287719, encodeId=1951128e7192e, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1514541, encodeId=04f415145416d, content=<a href='/topic/show?id=102f102e8375' target=_blank style='color:#2F92EE;'>#高钾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102783, encryptionId=102f102e8375, topicName=高钾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c5d010658633, createdName=ms7517674339485982, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538290, encodeId=7d37153829016, content=<a href='/topic/show?id=1258263835a' target=_blank style='color:#2F92EE;'>#低钠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26383, encryptionId=1258263835a, topicName=低钠)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9512951240, createdName=zz12341238, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070318, encodeId=fc4310e03189b, content=是极为不平静的一天。就是在这一, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Mon Nov 15 08:07:27 CST 2021, time=2021-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070311, encodeId=8fb110e0311e2, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=415c5624067, createdName=ms4000001739841053, createdTime=Mon Nov 15 07:07:11 CST 2021, time=2021-11-15, status=1, ipAttribution=)]
    2021-11-16 14698a10m84暂无昵称

    学习,谢谢

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1643774, encodeId=3aef1643e74d6, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Fri Dec 17 20:47:47 CST 2021, time=2021-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1208331, encodeId=f6161208331d7, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0eb2046086, createdName=1881eacd07m, createdTime=Sun Apr 03 11:00:49 CST 2022, time=2022-04-03, status=1, ipAttribution=), 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070864, encodeId=e1d010e086445, content=学习,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a25151353, createdName=14698a10m84暂无昵称, createdTime=Tue Nov 16 19:56:53 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287719, encodeId=1951128e7192e, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1514541, encodeId=04f415145416d, content=<a href='/topic/show?id=102f102e8375' target=_blank style='color:#2F92EE;'>#高钾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102783, encryptionId=102f102e8375, topicName=高钾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c5d010658633, createdName=ms7517674339485982, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538290, encodeId=7d37153829016, content=<a href='/topic/show?id=1258263835a' target=_blank style='color:#2F92EE;'>#低钠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26383, encryptionId=1258263835a, topicName=低钠)], attachment=null, authenticateStatus=null, createdAvatar=null, 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createdName=ms4000001739841053, createdTime=Mon Nov 15 07:07:11 CST 2021, time=2021-11-15, status=1, ipAttribution=)]
  7. 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GetPortalCommentsPageByObjectIdResponse(id=1514541, encodeId=04f415145416d, content=<a href='/topic/show?id=102f102e8375' target=_blank style='color:#2F92EE;'>#高钾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102783, encryptionId=102f102e8375, topicName=高钾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c5d010658633, createdName=ms7517674339485982, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538290, encodeId=7d37153829016, content=<a href='/topic/show?id=1258263835a' target=_blank style='color:#2F92EE;'>#低钠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26383, encryptionId=1258263835a, topicName=低钠)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9512951240, createdName=zz12341238, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070318, encodeId=fc4310e03189b, content=是极为不平静的一天。就是在这一, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Mon Nov 15 08:07:27 CST 2021, time=2021-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070311, encodeId=8fb110e0311e2, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=415c5624067, createdName=ms4000001739841053, createdTime=Mon Nov 15 07:07:11 CST 2021, time=2021-11-15, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1643774, encodeId=3aef1643e74d6, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Fri Dec 17 20:47:47 CST 2021, time=2021-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1208331, encodeId=f6161208331d7, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0eb2046086, createdName=1881eacd07m, createdTime=Sun Apr 03 11:00:49 CST 2022, time=2022-04-03, status=1, ipAttribution=), 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070864, encodeId=e1d010e086445, content=学习,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a25151353, createdName=14698a10m84暂无昵称, createdTime=Tue Nov 16 19:56:53 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287719, encodeId=1951128e7192e, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1514541, encodeId=04f415145416d, content=<a href='/topic/show?id=102f102e8375' target=_blank style='color:#2F92EE;'>#高钾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102783, encryptionId=102f102e8375, topicName=高钾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c5d010658633, createdName=ms7517674339485982, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538290, encodeId=7d37153829016, content=<a href='/topic/show?id=1258263835a' target=_blank style='color:#2F92EE;'>#低钠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26383, encryptionId=1258263835a, topicName=低钠)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9512951240, createdName=zz12341238, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070318, encodeId=fc4310e03189b, content=是极为不平静的一天。就是在这一, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Mon Nov 15 08:07:27 CST 2021, time=2021-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070311, encodeId=8fb110e0311e2, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=415c5624067, createdName=ms4000001739841053, createdTime=Mon Nov 15 07:07:11 CST 2021, time=2021-11-15, status=1, ipAttribution=)]
    2021-11-16 zz12341238
  9. [GetPortalCommentsPageByObjectIdResponse(id=1643774, encodeId=3aef1643e74d6, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Fri Dec 17 20:47:47 CST 2021, time=2021-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1208331, encodeId=f6161208331d7, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0eb2046086, createdName=1881eacd07m, createdTime=Sun Apr 03 11:00:49 CST 2022, time=2022-04-03, status=1, ipAttribution=), 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070864, encodeId=e1d010e086445, content=学习,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a25151353, createdName=14698a10m84暂无昵称, createdTime=Tue Nov 16 19:56:53 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287719, encodeId=1951128e7192e, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1514541, encodeId=04f415145416d, content=<a href='/topic/show?id=102f102e8375' target=_blank style='color:#2F92EE;'>#高钾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102783, encryptionId=102f102e8375, topicName=高钾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c5d010658633, createdName=ms7517674339485982, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538290, encodeId=7d37153829016, content=<a href='/topic/show?id=1258263835a' target=_blank style='color:#2F92EE;'>#低钠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26383, encryptionId=1258263835a, topicName=低钠)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9512951240, createdName=zz12341238, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070318, encodeId=fc4310e03189b, content=是极为不平静的一天。就是在这一, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Mon Nov 15 08:07:27 CST 2021, time=2021-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070311, encodeId=8fb110e0311e2, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=415c5624067, createdName=ms4000001739841053, createdTime=Mon Nov 15 07:07:11 CST 2021, time=2021-11-15, status=1, ipAttribution=)]
    2021-11-15 查查佳佳

    是极为不平静的一天。就是在这一

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1643774, encodeId=3aef1643e74d6, content=<a href='/topic/show?id=6236895092b' target=_blank style='color:#2F92EE;'>#血管事件#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89509, encryptionId=6236895092b, topicName=血管事件)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f99523187183, createdName=hukaixun, createdTime=Fri Dec 17 20:47:47 CST 2021, time=2021-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1208331, encodeId=f6161208331d7, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0eb2046086, createdName=1881eacd07m, createdTime=Sun Apr 03 11:00:49 CST 2022, time=2022-04-03, status=1, ipAttribution=), 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070864, encodeId=e1d010e086445, content=学习,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a25151353, createdName=14698a10m84暂无昵称, createdTime=Tue Nov 16 19:56:53 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1287719, encodeId=1951128e7192e, content=<a href='/topic/show?id=3c3d51e4459' target=_blank style='color:#2F92EE;'>#心血管事件风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51744, encryptionId=3c3d51e4459, topicName=心血管事件风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1514541, encodeId=04f415145416d, content=<a href='/topic/show?id=102f102e8375' target=_blank style='color:#2F92EE;'>#高钾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102783, encryptionId=102f102e8375, topicName=高钾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c5d010658633, createdName=ms7517674339485982, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538290, encodeId=7d37153829016, content=<a href='/topic/show?id=1258263835a' target=_blank style='color:#2F92EE;'>#低钠#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26383, encryptionId=1258263835a, topicName=低钠)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9512951240, createdName=zz12341238, createdTime=Tue Nov 16 12:47:47 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070318, encodeId=fc4310e03189b, content=是极为不平静的一天。就是在这一, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIrrxxDxnLic8t6EAs38Qfwo6H2h6JMleIgb9OSYf6LMnVDkQEqUXWoSDWboibjhOBI9SJDTXweqQIA/132, createdBy=50aa5321359, createdName=查查佳佳, createdTime=Mon Nov 15 08:07:27 CST 2021, time=2021-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070311, encodeId=8fb110e0311e2, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=415c5624067, createdName=ms4000001739841053, createdTime=Mon Nov 15 07:07:11 CST 2021, time=2021-11-15, status=1, ipAttribution=)]
    2021-11-15 ms4000001739841053

    不错

    0

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