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Stroke:中枢神经系统原发性血管炎的磁共振表现

2017-03-25 MedSci MedSci原创

目前,中枢神经系统原发性血管炎仍然具有挑战性。近期,一项发表在杂志Stroke上的文章旨在评估成人原发性脑血管炎中枢神经系统磁共振成像的概况,并确定在大型多中心队列研究中实质、脑膜和血管病变的分布情况。此项研究包括法国COVAC队列(中枢神经系统原发性血管炎患者队列)中的成人患者,其中包括活检或血管造影证实的中枢神经系统原发性血管炎以及脑磁共振成像的诊断。此项研究结果显示:共有60名患者符合纳入标

目前,中枢神经系统原发性血管炎仍然具有挑战性。近期,一项发表在杂志Stroke上的文章旨在评估成人原发性脑血管炎中枢神经系统磁共振成像的概况,并确定在大型多中心队列研究中实质、脑膜和血管病变的分布情况。

此项研究包括法国COVAC队列(中枢神经系统原发性血管炎患者队列)中的成人患者,其中包括活检或血管造影证实的中枢神经系统原发性血管炎以及脑磁共振成像的诊断

此项研究结果显示:共有60名患者符合纳入标准。平均年龄45岁(±12.9)。患者最初出现焦虑症(83%),头痛(53%),认知障碍(40%)和癫痫发作(38.3%)。在42%的患者中观察到的最常见的磁共振成像表现是多游离、双侧、远端急性中风病变后的中小动脉分布,主要是颈动脉循环分布。也观察到了出血性梗死和实质性出血(55%)。在26%的患者中发现急性凸性蛛网膜下腔出血,42%表现出优势的脑膜增生,这一现象在活检证实的患者中更为普遍(60%vs.28%; P = 0.04)。 7例患者有肿瘤样表现。77%的磁共振血管造影检查有异常,分别显示57%和61%的近端/远端狭窄。

此项研究表明:中枢神经系统的成人原发性血管炎是一种异质性疾病,多重,远端和双侧急性中风是磁共振成像中最常见的实质性病变。

原始出处:
Boulouis G, de Boysson H, et al. Primary Angiitis of the Central Nervous System: Magnetic Resonance Imaging Spectrum of Parenchymal, Meningeal, and Vascular Lesions at Baseline. Stroke. 2017 Mar 22. pii: STROKEAHA.116.016194. doi: 10.1161/STROKEAHA.116.016194. 

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    2017-04-03 虈亣靌

    全程参与实验,即学即用,多次实践,确保掌握所学技术。

    0

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    2017-04-01 baihao215

    涨姿势了,谢谢小编

    0

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    2017-03-26 shaosai

    好好学习,涨知识

    0

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    2017-03-26 1e0ece0dm09(暂无匿称)

    谢谢指点迷津

    0

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