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Diabetes Metab Syndr:白藜芦醇对伴2型糖尿病的慢性牙周炎患者牙周炎症的影响

2020-04-19 MedSci原创 MedSci原创

糖尿病和牙周疾病是两种常见的慢性疾病,相互间存在密切关联,会影响公共卫生和生活质量。本研究旨在探究补充白藜芦醇辅助非手术牙周治疗对2型糖尿病牙周疾病患者的炎症,抗氧化剂和牙周标志物的影响。

糖尿病和牙周疾病是两种常见的慢性疾病,相互间存在密切关联,会影响公共卫生和生活质量。本研究旨在探究补充白藜芦醇辅助非手术牙周治疗对2型糖尿病牙周疾病患者的炎症,抗氧化剂和牙周标志物的影响。

 

在这项随机临床试验中,将43名糖尿病和慢性牙周炎患者随机分为两个干预组和对照组,分别接受白藜芦醇补充剂或安慰剂治疗4周。在干预前和干预后,测量血清白细胞介素6IL6),肿瘤坏死因子α(TNFα),总抗氧化能力(TAC)和临床附着丧失(CAL)作为牙周标志物的主要指标。

 

结果显示,在干预组中,干预后平均血清IL6水平显著降低(P = 0.039)(2.19±1.091.58±1.06)。干预后两组间IL6TNFα,TACCAL的平均水平无明显差异。

 

综上所述,该研究结果表明,虽然每天补充白藜芦醇可能不会改变TNFα,TACCAL,但有益于降低血清IL6的水平。因此,建议进一步研究以探究白藜芦醇与NST一起对牙周状况的影响。

 

原始出处:

 

Ahmad Zare JavidRazie Hormoznejad, et al., Impact of Resveratrol Supplementation on Inflammatory, Antioxidant, and Periodontal Markers in Type 2 Diabetic Patients With Chronic Periodontitis. Diabetes Metab Syndr. Jul-Aug 2019;13(4):2769-2774. doi: 10.1016/j.dsx.2019.07.042. Epub 2019 Jul 24.

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    2020-08-22 guojianrong
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    2020-11-16 lovetcm

    #白藜芦醇#对伴#2型糖尿病#的慢性#牙周炎#患者牙周炎症的影响

    0

  5. 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    2021-02-10 一闲
  6. 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  8. 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  9. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sun Apr 19 23:30:45 CST 2020, time=2020-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=381913, encodeId=785d38191333, content=学习了,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=152, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Sun Apr 19 22:32:23 CST 2020, time=2020-04-19, status=1, ipAttribution=)]
    2020-04-19 misszhang

    谢谢MedSci提供最新的资讯

    0

  10. 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