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JAHA:急性缺血性脑卒中透析患者结局的变化趋势!

2018-06-15 xing.T MedSci原创

由此可见,与非透析患者相比,透析患者的AIS发病率高出8倍。他们具有较高的调整后住院死亡、败血症和输血风险,更长的住院时间和更高的成本。未来研究很有必要确定降低透析人群AIS风险的预防策略。

目前缺乏关于持续透析患者发生急性缺血性脑卒中(AIS)特点和结局的资料。

近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员使用全国住院样本来评估透析患者AIS的发病率、治疗模式和结局的当代趋势。在2003至2014年间该研究共收治了930010例AIS患者,其中透析患者有13642例(1.5%)。

总体而言,透析患者AIS的发生率显著降低(趋势P<0.001),而在非透析患者中AIS发生率仍保持稳定(趋势P=0.78)。与非透析患者相比,透析患者年龄较小(67±13岁 vs. 71±15岁,P<0.001),主要合并症患病率较高。因AIS住院的透析患者黑人比例占35.2%,而非透析的AIS患者黑人占16.7%(P<0.001)。倾向评分匹配后,透析组住院死亡率高于对照组(7.6% vs. 5.2%,P<0.001),但病死率随时间延长而缩短(趋势P<0.001)。出血和消化道出血率相似,但输血在透析组更为常见。两组严重残疾指标(气管造口术、胃造口术、机械通气和非家庭出院)的比率也相似。然而,透析患者住院时间较长,并且急性护理总费用增加了25%。

由此可见,与非透析患者相比,透析患者的AIS发病率高出8倍。他们具有较高的调整后住院死亡、败血症和输血风险,更长的住院时间和更高的成本。未来研究很有必要确定降低透析人群AIS风险的预防策略。

原始出处:

Fahad Alqahtani,.et al. Temporal Trends in the Outcomes of Dialysis Patients Admitted With Acute Ischemic Stroke.JAHA.2018. https://doi.org/10.1161/JAHA.118.008686

本文系梅斯医学(MedSci)原创编译整理,转载需授权!


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    2018-06-17 zwjnj2

    好好学习天天学习认真学习

    0

  4. 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  5. 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createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Jun 16 06:13:59 CST 2018, time=2018-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324525, encodeId=c7a232452590, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat Jun 16 00:36:46 CST 2018, time=2018-06-16, status=1, ipAttribution=)]
    2018-06-17 zhaohui6731
  6. 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  7. 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createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Jun 16 06:13:59 CST 2018, time=2018-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324525, encodeId=c7a232452590, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat Jun 16 00:36:46 CST 2018, time=2018-06-16, status=1, ipAttribution=)]
    2018-06-17 liuchuan1982

    未来研究很有必要确定降低透析人群AIS风险的预防策略.

    0

  9. 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createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Jun 16 06:13:59 CST 2018, time=2018-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324525, encodeId=c7a232452590, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat Jun 16 00:36:46 CST 2018, time=2018-06-16, status=1, ipAttribution=)]
    2018-06-16 飛歌

    厉害了我的哥

    0

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createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sat Jun 16 06:13:59 CST 2018, time=2018-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=324525, encodeId=c7a232452590, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat Jun 16 00:36:46 CST 2018, time=2018-06-16, status=1, ipAttribution=)]
    2018-06-16 1209e435m98(暂无昵称)

    学习了.谢谢分享

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