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Hypertension:主动脉扩张性降低可在儿童期发现

2014-11-04 cath 编译 医学论坛网

芬兰一项研究表明,与年龄相关的血管可扩张性显著降低在年龄较小时就已存在了,与女孩相比,这种降低更常见于男孩。主动脉纵向进展和颈动脉扩张性与左心室质量改变有相关性。论文10月27日在线发表于《高血压》(HYPERTENSION)杂志。 该研究旨在对年龄、性别和低饱和脂肪饮食咨询对儿童至成年早期人群动脉可扩张性的影响,并评估动脉可扩张性与左心室质量的相关性。在受试者在年龄11岁、13岁、15

芬兰一项研究表明,与年龄相关的血管可扩张性显著降低在年龄较小时就已存在了,与女孩相比,这种降低更常见于男孩。主动脉纵向进展和颈动脉扩张性与左心室质量改变有相关性。论文10月27日在线发表于《高血压》(HYPERTENSION)杂志。

该研究旨在对年龄、性别和低饱和脂肪饮食咨询对儿童至成年早期人群动脉可扩张性的影响,并评估动脉可扩张性与左心室质量的相关性。在受试者在年龄11岁、13岁、15岁、17岁和19岁时对其腹主动脉扩张和正常颈动脉进行重复评估。

结果显示,主动脉和颈动脉可扩张性随年龄增加而降低(P<0.0001)。男孩的可扩张指标普遍较低(P<0.0001),且随年龄增加下降的更快。低饱和脂肪饮食咨询与动脉可扩张性不显著相关。左心室质量岁年龄增加(P<0.0001),并在男孩中增加更显著(P<0.0001)。

原始出处:

Mikola H1, Pahkala K2, Rönnemaa T2, Viikari JS2, Niinikoski H2, Jokinen E2, Salo P2, Simell O2, Juonala M2, Raitakari OT2.Distensibility of the Aorta and Carotid Artery and Left Ventricular Mass From Childhood to Early Adulthood.Hypertension. 2014 Oct 27. pii: HYPERTENSIONAHA.114.03316. [Epub ahead of print]


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    2015-01-30 feather89
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    2014-11-23 lsj637
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