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Lancet Neurol:淀粉样血管病相关脑叶出血的实用诊断工具

2018-04-06 杨中华 脑血管病及重症文献导读

2018年3月,来自英国的Mark A Rodrigues等在Lancet Neurology上发表了他们的研究结果,他们纳入了初次脑出血(CT诊断),并且死亡后进行了尸体解剖的患者。

2018年3月,来自英国的Mark A Rodrigues等在Lancet Neurology上发表了他们的研究结果,他们纳入了初次脑出血(CT诊断),并且死亡后进行了尸体解剖的患者。

他们发现预测CAA相关脑叶出血的三个变量为蛛网膜下腔出血,出血指样突起,以及APOEε4。采用这三个变量诊断CAA相关脑叶出血的预测模型具有非常优秀的识别能力(c statistic 0.92,95%CI 0.86–0.98)。

下图,按照三个预测变量,脑叶出血病因:中等或严重CAA的可能性:



最终作者认为采用CT和APOE基因的CAA相关脑叶出血的预测模型具有优秀的识别能力,但是尚需外部验证。

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    2018-06-10 yinhl1978
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    2018-10-13 howi
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    2018-04-06 wzb521zf

    一起学习学习

    0

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    2018-04-06 13718711b3m

    学习了.获益匪浅.感谢分享

    0

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