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Nat Commun:复旦学者统计,武汉新冠**波大流行的疾病负担和临床严重程度

2020-10-30 haibei MedSci原创

症状病例、就诊、住院和死亡的比率分别估计为每10万人796(95% CI:703-977)、489(472-509)、370(358-384)和36.2(35.0-37.3)。

截至2020年7月26日,全球已有188个国家受到2019年新型冠状病毒病(COVID-19)的影响,全球共报告15,745,102例COVID-19病例,644,661人死亡。COVID-19具有广泛的严重性。

在血清学确认的感染中,只有一部分会出现症状。一部分有症状的病例可能会寻求医疗护理,当他们可以通过监测系统确定时,需要住院治疗,甚至面临死亡。住院是一个重要的衡量标准,因为它决定了流行病对卫生保健系统造成的压力。此外,死亡人数与规划大流行病应对措施高度相关,因为死亡率是卫生当局通常旨在尽量减少的结果。

2019年新型冠状病毒病(COVID-19)首次在中国武汉被报道,最初一波密集的社区传播被干预措施切断。利用多个数据源,最近来自复旦大学的研究人员在Nature Communications杂志发文,估计了2019年12月1日至2020年3月31日武汉市COVID-19的疾病负担和按年龄划分的临床严重程度。

研究人员的估计考虑了实验室检测的敏感性、前瞻性社区筛查和医疗寻求行为。症状病例、就诊、住院和死亡的比率分别估计为每10万人796(95% CI:703-977)、489(472-509)、370(358-384)和36.2(35.0-37.3)。

武汉市发生的COVID-19疫情在住院率和死亡率方面比2009年流感大流行或季节性流感负担更高,临床严重程度与1918年流感大流行相似。

研究人员的比较将COVID-19大流行置于大背景之下,有助于指导干预策略,以及对COVID-19可能再次出现的准备工作。

 

原始出处:

Juan Yang et al. Disease burden and clinical severity of the first pandemic wave of COVID-19 in Wuhan, China. Nature Communications (2020). 

 

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    2021-03-12 liye789132251
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    2020-11-01 saikp
  6. [GetPortalCommentsPageByObjectIdResponse(id=2087816, encodeId=549c208e8162b, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Fri May 07 14:32:26 CST 2021, time=2021-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1930180, encodeId=bffa193018097, content=<a href='/topic/show?id=4303226682e' target=_blank style='color:#2F92EE;'>#临床严重程度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22668, encryptionId=4303226682e, topicName=临床严重程度)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=362b271, createdName=zexyw01, createdTime=Tue Jun 08 22:32:26 CST 2021, time=2021-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1884764, encodeId=16011884e64e5, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Fri Mar 12 06:32:26 CST 2021, time=2021-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1333622, encodeId=9851133362253, content=<a href='/topic/show?id=1a1de07305e' target=_blank style='color:#2F92EE;'>#疾病负担#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70730, encryptionId=1a1de07305e, topicName=疾病负担)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Nov 01 14:32:26 CST 2020, time=2020-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538598, encodeId=4aa91538598d8, content=<a href='/topic/show?id=751e42660f1' target=_blank style='color:#2F92EE;'>#复旦#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42660, encryptionId=751e42660f1, topicName=复旦)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6c312994908, createdName=saikp, createdTime=Sun Nov 01 14:32:26 CST 2020, time=2020-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895802, encodeId=8a5489580227, content=值得学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210724/c645b03bf7334ae9851463b07f0c8f68/b29977d0d19a42f9881060d301f0a012.jpg, createdBy=3f901635259, createdName=qingzipost, createdTime=Sat Oct 31 07:18:07 CST 2020, time=2020-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028712, encodeId=15ec1028e1275, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sat Oct 31 02:32:26 CST 2020, time=2020-10-31, status=1, ipAttribution=)]
    2020-10-31 qingzipost

    值得学习!

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2087816, encodeId=549c208e8162b, content=<a href='/topic/show?id=490750196b' target=_blank style='color:#2F92EE;'>#COMMUN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5019, encryptionId=490750196b, topicName=COMMUN)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Fri May 07 14:32:26 CST 2021, time=2021-05-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1930180, encodeId=bffa193018097, content=<a href='/topic/show?id=4303226682e' target=_blank style='color:#2F92EE;'>#临床严重程度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22668, encryptionId=4303226682e, topicName=临床严重程度)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=362b271, createdName=zexyw01, createdTime=Tue Jun 08 22:32:26 CST 2021, time=2021-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1884764, encodeId=16011884e64e5, content=<a href='/topic/show?id=3b2112532d8' target=_blank style='color:#2F92EE;'>#Nat#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12532, encryptionId=3b2112532d8, topicName=Nat)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e6f107, createdName=liye789132251, createdTime=Fri Mar 12 06:32:26 CST 2021, time=2021-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1333622, encodeId=9851133362253, content=<a href='/topic/show?id=1a1de07305e' target=_blank style='color:#2F92EE;'>#疾病负担#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70730, encryptionId=1a1de07305e, topicName=疾病负担)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Nov 01 14:32:26 CST 2020, time=2020-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1538598, encodeId=4aa91538598d8, content=<a href='/topic/show?id=751e42660f1' target=_blank style='color:#2F92EE;'>#复旦#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42660, encryptionId=751e42660f1, topicName=复旦)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6c312994908, createdName=saikp, createdTime=Sun Nov 01 14:32:26 CST 2020, time=2020-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895802, encodeId=8a5489580227, content=值得学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210724/c645b03bf7334ae9851463b07f0c8f68/b29977d0d19a42f9881060d301f0a012.jpg, createdBy=3f901635259, createdName=qingzipost, createdTime=Sat Oct 31 07:18:07 CST 2020, time=2020-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1028712, encodeId=15ec1028e1275, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sat Oct 31 02:32:26 CST 2020, time=2020-10-31, status=1, ipAttribution=)]
    2020-10-31 公卫新人

    新冠肺炎,疫情何时才能消失

    0

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