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Cancer:焦虑抑郁真的会导致癌症死亡率增加

2017-06-27 cailingrui MedSci原创

根据最近的一项研究结果,严重的情绪低落,特别是焦虑和抑郁,可能与某些癌症的死亡率增加紧密相关。尽管这是一项观察性研究,研究人员认为它为情绪不佳导致癌症的某些不良后果这一猜想,提供了更多有利的证据。他们列举了先前的一项实验研究的证据,说明了焦虑抑郁和心血管疾病发病率升高之间的联系。

根据最近的一项研究结果,严重的情绪低落,特别是焦虑和抑郁,可能与某些癌症的死亡率增加紧密相关。尽管这是一项观察性研究,研究人员认为它为情绪不佳导致癌症的某些不良后果这一猜想,提供了更多有利的证据。他们列举了先前的一项实验研究的证据,说明了焦虑抑郁和心血管疾病发病率升高之间的联系。

就这项研究而言,来自英国伦敦大学学院,苏格兰爱丁堡大学和澳大利亚悉尼大学的科学家们通力合作,采用了来自1994到2008年间的16项研究结果数据,其中13项研究来自英国,3项来自苏格兰。一共163,363名大于16岁的被试,实验开始时均未检测患有癌症,在后期多年的随访调查中,4,353名参与者不幸因癌症离世。在这期间,研究人员通过普通问卷调查的形式,对参与者的情绪低落程度进行评分。

来自英国伦敦大学学院的项目负责人David Batty博士提到,在控制年龄、性别、教育程度、BMI、抽烟喝酒习惯和社会经济学背景等一系列变量后,研究人员发现,与极少收到情绪影响组的参与者相比,那些情绪极端低落的受试,在白血病、肠癌、前列腺癌、胰腺癌和食管癌中都一致的表现出死亡率显著上升的趋势。

这种癌症和情绪的关联性反过来也可以说的通,未确诊或是癌症早期的不确定性确实会对情绪有潜在的影响。针对这种可能性,研究人员排除了那些在随访开始前五年就病逝的参与者,进行了进一步的分析。结果依然和之前得到的一致,严重的情绪低落与癌症死亡率之间存在紧密联系。

同时,Batty博士也指出,还需要进一步的研究来揭示焦虑抑郁影响癌症死亡率的真正作用机制。 

原始出处:

Printz, Carrie. Anxiety and depression may contribute to an increased risk of death in some cancers. Cancer 123.13 (2017): 2389-2389.

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    2017-06-28 jambiya
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    2017-06-28 日月生辉

    心理愉快对身体健康及心理健康什分重要!

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高考已经来临,很多考生可能会出现情绪焦虑、失眠等状况。面对这种情况考生该如何调整自己的状态?精神科医生该如何帮助考生摆脱焦虑?梅斯小编整理了焦虑症相关指南,供大家参考! 一、综合医院焦虑、抑郁与躯体化症状诊断治疗的专家共识 中华医学会神经病学分会神经心理学与行为神经病学组组织相关专家按照循证医学原则,参考美国精神病联合会、加拿大焦虑障碍协会、美国临床肿瘤学会等专业学会制定的最新指南,结

Allergy:特应性皮炎与焦虑、抑郁和自杀意念有关,但与住院或自杀无关!

由此可见,在AD患者中,抑郁、焦虑和自杀意念较为常见,但不导致精神病咨询、住院或自杀增加。

J Clin Oncol:癌症幸存者焦虑和抑郁用药情况 你造吗?

专家点评:奥氮平的off label使用中,有一种作用便是止吐,临床上有应用,指南也有所更新;而且奥氮平具有价更廉的优势。此外,对于难治性高血压,也可以使用奥氮平,地西泮等药物,主要是发挥其镇静的作用。

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