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Photodiagnosis Photodyn Ther:辅助性PDT是否有效治疗高血糖患者的牙周炎症和降低HbA1c水平

2018-03-01 MedSci MedSci原创

本研究旨在评估刮治和根面平整(SRP)时联合或不联合辅助光动力学治疗(PDT)治疗高血糖患者牙周病(PD)的效果。方法:检索2017年12月前数据库(MEDLINE,EMBASE和CENTRAL)在线发表的文章。所提到的PICO问题是:“在高血糖患者中通过临床牙周和血糖参数辅助PDT对非手术牙周治疗的有效性?”结果:纳入了4项临床试验和1项实验研究。辐射能量、功率输出、功率密度和辐照持续时间分别为

本研究旨在评估刮治和根面平整(SRP)时联合或不联合辅助光动力学治疗(PDT)治疗高血糖患者牙周病(PD)的效果。

方法:
检索2017年12月前数据库(MEDLINE,EMBASE和CENTRAL)在线发表的文章。所提到的PICO问题是:“在高血糖患者中通过临床牙周和血糖参数辅助PDT对非手术牙周治疗的有效性?”

结果:
纳入了4项临床试验和1项实验研究。辐射能量、功率输出、功率密度和辐照持续时间分别为2.79 Jcm-2,150 mW,428 mWcm-2和133s。所有报告临床牙周和代谢参数的研究都表明,aPDT在随访期间可有效治疗高血糖患者的牙周炎症。与SRP比较,没有一项研究显示PDT与单独使用SRP相比有更多益处。三项研究表明SRP联合或不联合aPDT对HbA1c水平没有影响。一项研究显示辅助aPDT患者HbA1c的水平与随访时单独SRP相比明显降低。

结论:
与SRP相比,辅助性PDT是否有效治疗高血糖患者的牙周炎症和降低HbA1c水平仍然值得商榷。

原始出处:

Javed F, Salehpoor D, et al., Is adjunctive photodynamic therapy more effective than scaling and root planing alone in the treatment of periodontal disease in hyperglycemic patients? A systematic review. Photodiagnosis Photodyn Ther. 2018 Feb 19. pii: S1572-1000(18)30029-2. doi: 10.1016/j.pdpdt.2018.02.012. 

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    2018-03-23 江川靖瑶
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    2018-03-18 Smile2680
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    2018-10-15 liuxiaona
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