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Lancet Psychiatry:自闭症患者更有可能使用娱乐性药物进行自我治疗

2021-07-03 MedSci原创 MedSci原创

据联合国估计,目前,全球已有逾7000万人患有自闭症。而在新冠疫情蔓延之时,本就存在社交沟通等多方面障碍的他们,正身处更为严峻的社会环境当中。

据联合国估计,目前,全球已有逾7000万人患有自闭症。而在新冠疫情蔓延之时,本就存在社交沟通等多方面障碍的他们,正身处更为严峻的社会环境当中。

CCO

近日,来自剑桥大学的研究人员发现,自闭症患者滥用药物以及酗酒的可能性较小。然而,自闭症患者使用娱乐性药物(如大麻、可卡因和安非他明)的可能性是非自闭症患者的近 9 倍。研究结果发表在Lancet Psychiatry杂志上。

在这项研究中,研究人员使用调查中两个重叠但独立的样本(一个样本有完整的定量回答,一个样本有完整的定性回答),对365716-90岁的自闭症和非自闭症患者进行了有关药物滥用的匿名在线问卷调查。在排除了回答缺失或不完整的问卷后,研究人员对2386名参与者进行了定量分析,包含1183名自闭症患者和1203名非自闭症患者,其中1571名为女性。此外,对919名参与者进行了定性分析,包括429名自闭症患者和490名非自闭症患者,其中569名为女性。

研究结果显示,与非自闭症患者,自闭症患者酗酒曾经使用毒品的几率比较小。只有16%的自闭症患者和22%非自闭症患者,报告平均每周有3天或更多的时间喝酒。同样,4%的自闭症患者报告曾酗酒,而非自闭症患者则有8%。在男性自闭症患者中报告吸烟的几率也很少。

自闭症患者与非自闭症患者的药物使用比较.

然而,尽管酗酒和吸烟几率很低,但在定性分析中发现,与非自闭症患者相比,自闭症患者报告使用娱乐性物质来管理行为的可能性要高出近9OR 8-892-05-81-12p=0-0017),报告使用娱乐性物质来管理心理健康症状的可能性也更大OR 3-081-18-9-08p=0-032)。

研究者表示,虽然我们的一些结果表明总体上使用药物的可能性较低,但医生不应假设自闭症患者没有使用药物。如果没有医疗保健专业人员的专业指导,自闭症患者不应该进行自我用药治疗。考虑到药物使用、心理健康和行为管理之间的复杂关联,特别是伪装和补偿,确定新形式的有效支持是当务之急。

原始出处

Weir, E., Allison, C., & Baron-Cohen, S. Understanding the substance use of autistic adults: a mixed methods approach. The Lancet Psychiatry (2021).

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    2021-12-18 howi
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    2021-07-05 xiongke014
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    2021-07-04 小小医者

    #自闭症#未来要靠#数字治疗#来解决

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1831227, encodeId=48fc183122eaf, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sat Dec 18 13:02:50 CST 2021, time=2021-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1792271, encodeId=27fa1e92271cf, content=<a href='/topic/show?id=696a14818df' target=_blank style='color:#2F92EE;'>#Psychiatry#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14818, encryptionId=696a14818df, topicName=Psychiatry)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Mon Jul 19 07:02:50 CST 2021, time=2021-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1527804, encodeId=ca39152e8040f, content=<a href='/topic/show?id=68b5863e5d2' target=_blank style='color:#2F92EE;'>#自闭#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86375, encryptionId=68b5863e5d2, topicName=自闭)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=159511872623, createdName=xiongke014, createdTime=Mon Jul 05 09:02:50 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=995975, encodeId=08ee9959e5ab, content=<a href='/topic/show?id=4266863e7bd' target=_blank style='color:#2F92EE;'>#自闭症#</a>未来要靠<a href='/topic/show?id=5d33104369ad' target=_blank style='color:#2F92EE;'>#数字治疗#</a>来解决, beContent=null, objectType=article, channel=null, level=null, likeNumber=200, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86377, encryptionId=4266863e7bd, topicName=自闭症), TopicDto(id=104369, encryptionId=5d33104369ad, topicName=数字治疗)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Sun Jul 04 07:28:54 CST 2021, time=2021-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1034378, encodeId=b08910343e8de, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Sat Jul 03 21:02:50 CST 2021, time=2021-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=995849, encodeId=0cbc99584927, content=已读,真是受益匪浅呀。, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Sat Jul 03 19:18:20 CST 2021, time=2021-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=995846, encodeId=ccb19958461d, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/e8756bb97c3947f799b675e8f7703414/d4311af75c2a4fadb5b4daae9c5847e1.jpg, createdBy=6f7e5540521, createdName= ccz, createdTime=Sat Jul 03 18:44:59 CST 2021, time=2021-07-03, status=1, ipAttribution=)]
    2021-07-03 goodbing

    顶刊就是不一样,质量很高,内容精彩!学到很多

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1831227, encodeId=48fc183122eaf, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sat Dec 18 13:02:50 CST 2021, time=2021-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1792271, encodeId=27fa1e92271cf, content=<a href='/topic/show?id=696a14818df' target=_blank style='color:#2F92EE;'>#Psychiatry#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14818, encryptionId=696a14818df, topicName=Psychiatry)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Mon Jul 19 07:02:50 CST 2021, time=2021-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1527804, encodeId=ca39152e8040f, content=<a href='/topic/show?id=68b5863e5d2' target=_blank style='color:#2F92EE;'>#自闭#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86375, encryptionId=68b5863e5d2, topicName=自闭)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=159511872623, createdName=xiongke014, createdTime=Mon Jul 05 09:02:50 CST 2021, time=2021-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=995975, encodeId=08ee9959e5ab, content=<a href='/topic/show?id=4266863e7bd' target=_blank style='color:#2F92EE;'>#自闭症#</a>未来要靠<a href='/topic/show?id=5d33104369ad' target=_blank style='color:#2F92EE;'>#数字治疗#</a>来解决, beContent=null, objectType=article, channel=null, level=null, likeNumber=200, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86377, encryptionId=4266863e7bd, topicName=自闭症), TopicDto(id=104369, encryptionId=5d33104369ad, topicName=数字治疗)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Sun Jul 04 07:28:54 CST 2021, time=2021-07-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1034378, encodeId=b08910343e8de, content=顶刊就是不一样,质量很高,内容精彩!学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=goodbing, createdTime=Sat Jul 03 21:02:50 CST 2021, time=2021-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=995849, encodeId=0cbc99584927, content=已读,真是受益匪浅呀。, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f03a5433387, createdName=ms5000000518166734, createdTime=Sat Jul 03 19:18:20 CST 2021, time=2021-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=995846, encodeId=ccb19958461d, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/e8756bb97c3947f799b675e8f7703414/d4311af75c2a4fadb5b4daae9c5847e1.jpg, createdBy=6f7e5540521, createdName= ccz, createdTime=Sat Jul 03 18:44:59 CST 2021, time=2021-07-03, status=1, ipAttribution=)]
    2021-07-03 ms5000000518166734

    已读,真是受益匪浅呀。

    0

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    2021-07-03 ccz

    学习了

    0

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