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Clin Oral Implants Res:益生菌在非手术治疗的种植体周围炎中的作用

2020-05-31 MedSci原创 MedSci原创

探讨双菌株乳酸菌复方益生菌对非手术治疗初期种植体周围炎的临床和微生物学意义。

探讨双菌株乳酸菌复方益生菌对非手术治疗初期种植体周围炎的临床和微生物学意义。

 

本随机双盲研究以初始种植体周围炎患者为研究对象,即最大平均探诊深度为6mm、最大骨质丧失为3mm的初始种植体周围炎,与负荷相比,最大平均探诊深度为6mm,最大骨质损失为3mm。对患者进行了全口预防,并对种植体周围炎部位进行了去骨化处理。随后,在种植体周围炎部位进行局部应用研究用滴剂,并发放研究用菱形糖。益生菌组的患者接受含有L. reuteri(ATCC PTA 5289和DSM 17938)的滴剂和药水,对照组的患者接受安慰剂产品。在种植体水平上的测量结果是出血、探诊深度和牙菌斑。还记录了全口出血和牙菌斑评分。从舌部、唾液和种植体周围的龈下采集了微生物样本。

 

结果显示,所有的临床参数在12周和24周后都明显下降。在种植体水平上,唯一具有统计学意义的差异是益生菌组与对照组相比,牙菌斑水平的下降幅度更大(24周时P = .002)。在全口牙水平上,唯一的组间差异是益生菌组与对照组相比,益生菌组的全口牙出血量减少得更多(24周时P < .001)。关于微生物学结果,在任何时间点上都没有发现组内和组间的显著差异。

 

综上所述,该研究结果表明,没有发现使用L.reuteri益生菌治疗牙周炎的辅助作用。

 

原始出处:

 

Isabelle Laleman, Martine Pauwels, et al., The Usage of a Lactobacilli Probiotic in the Non-Surgical Therapy of Peri-Implantitis: A Randomized Pilot Study. Clin Oral Implants Res. 2020 Jan;31(1):84-92. doi: 10.1111/clr.13555. Epub 2019 Nov 25.

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    2021-01-22 xuyu
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    2021-05-16 huangdf
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    2021-01-26 xuyong536
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    2020-11-02 小几洁
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    2020-05-31 wxl882001

    了解一下

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