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Lancet:潜蚤病:一目了然的诊断——案例报道

2016-07-20 MedSci MedSci原创

22岁的日本女性去乌干达Manafwa区旅游两周后,右脚的大拇指出现持续性疼痛伴皮疹10天。她指出在学生户外活动期间都穿了袜子和鞋子,只在郊区宾馆附近穿着凉鞋未穿袜子。 体检发现:该患者右脚趾第一指甲处出现黄白色结节,直径5 mm,在结节的中央有黑色的斑点(图A)。由此,我们怀疑是3期潜蚤病,在局麻下切开结节,在结节中发现了大量的虫卵(图B),同时给予了破伤风抗毒素。

22岁的日本女性去乌干达Manafwa区旅游两周后,右脚的大拇指出现持续性疼痛伴皮疹10天。她指出在学生户外活动期间都穿了袜子和鞋子,只在郊区宾馆附近穿着凉鞋未穿袜子。

体检发现:该患者右脚趾第一指甲处出现黄白色结节,直径5 mm,在结节的中央有黑色的斑点(图A)。由此,我们怀疑是3期潜蚤病,在局麻下切开结节,在结节中发现了大量的虫卵(图B),同时给予了破伤风抗毒素。


立体显微镜下检测为穿皮潜蚤,体长0.5 mm,伴虫卵。7天后伤口损伤完全愈合,无再次感染征象(图C)。


潜蚤病是一种由雌性沙地跳蚤(穿皮跳蚤)导致的体表寄生疾病,主要分布于中南美洲,加勒比海及撒哈拉以南的非洲。主要的宿主是动物。一旦在人体寄生,小小的跳蚤可以在1-3周内增长到10mm,产下数百个卵。潜蚤病对流行区居民的健康是很大的威胁,会导致长期的活动障碍,制动,慢性疼痛,自行切除会导致威胁生命的二次细菌感染,如破伤风和血源性感染。虽然手术切除是一种有效的治疗方法,但局部使用二甲聚硅氧烷可减少潜在的不良反应。

潜蚤病是一种人畜共患的疾病,可划分为不同阶段,根据寄生的雌性沙地跳蚤的阶段不同,可产生不同的症状,使诊断变得困难。旅行者在流行区应注意穿着衣物和袜子。

原始出处:

Takashi Matono, Yasuyuki Kato, Rie Yotsu, Norio Ohmagari,Tungiasis: diagnosis at a glance,Lancet 2016; 388: 275


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    2017-02-08 howi
  2. [GetPortalCommentsPageByObjectIdResponse(id=1828544, encodeId=a0fe182854470, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Wed Feb 08 19:51:00 CST 2017, time=2017-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1957811, encodeId=42b0195e81150, content=<a href='/topic/show?id=27fb66e1927' target=_blank style='color:#2F92EE;'>#潜蚤病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66719, encryptionId=27fb66e1927, topicName=潜蚤病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Thu Sep 29 18:51:00 CST 2016, time=2016-09-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=141731, encodeId=d5b8141e31f3, content=文章很棒,继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Oct 08 08:28:17 CST 2016, time=2016-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=94071, encodeId=2032940e105, content=为什么不能收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e54157458, createdName=sydengbc, createdTime=Thu Jul 21 21:03:00 CST 2016, time=2016-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93757, encodeId=f19993e57b9, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=154, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Jul 20 08:13:00 CST 2016, time=2016-07-20, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1828544, encodeId=a0fe182854470, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Wed Feb 08 19:51:00 CST 2017, time=2017-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1957811, encodeId=42b0195e81150, content=<a href='/topic/show?id=27fb66e1927' target=_blank style='color:#2F92EE;'>#潜蚤病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66719, encryptionId=27fb66e1927, topicName=潜蚤病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Thu Sep 29 18:51:00 CST 2016, time=2016-09-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=141731, encodeId=d5b8141e31f3, content=文章很棒,继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Oct 08 08:28:17 CST 2016, time=2016-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=94071, encodeId=2032940e105, content=为什么不能收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e54157458, createdName=sydengbc, createdTime=Thu Jul 21 21:03:00 CST 2016, time=2016-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93757, encodeId=f19993e57b9, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=154, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Jul 20 08:13:00 CST 2016, time=2016-07-20, status=1, ipAttribution=)]
    2016-10-08 1e10c84am36(暂无匿称)

    文章很棒,继续学习

    0

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    2016-07-21 sydengbc

    为什么不能收藏

    0

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    2016-07-20 doctorJiangchao

    继续关注

    0

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