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Anesthesiology:老年患者更易出现术后残余肌松

2015-10-11 张森 译 MedSci原创

老年患者在进行全身麻醉时,发生麻醉相关并发症的风险显著增加。老年患者术后残余肌松是指TOF的T4/T1小于0.9,这可能会加剧先前存在的肌无力以及呼吸功能障碍。近期,来自芝加哥大学普利兹克医学院的研究人员,进行了一项有关老年患者(70-90岁)和年轻患者(18-50岁)术后残余肌松的发生率及相关不良事件的研究。本次研究的数据前瞻性的收集自150位年轻患者以及150位老年患者。在患者进入麻醉复苏室(

老年患者在进行全身麻醉时,发生麻醉相关并发症的风险显著增加。老年患者术后残余肌松是指4个连续的成串的T4/T1小于0.9,这可能会加剧先前存在的肌无力以及呼吸功能障碍。近期,来自芝加哥大学普利兹克医学院的研究人员,进行了一项有关老年患者(70-90岁)和年轻患者(18-50岁)术后残余肌松的发生率及相关不良事件的研究。

本次研究的数据前瞻性的收集自150位年轻患者以及150位老年患者。在患者进入麻醉复苏室(PACU)时对四个成串的T4/T1比值进行测量。在气管拔管后,将患者转送至麻醉复苏室期间,进入麻醉复苏室30min,及住院期间对患者呼吸系统不良事件进行检测。对患者术后肌无力进行量化,并对患者在麻醉复苏室及住院的时间进行测算。

结果显示,老年患者术后残余肌松的发生率为57.7%,年轻患者为30.0%。老年患者出现气道阻塞、血氧过低、肌无力症状及体征、术后肺部并发症、麻醉复苏室及住院时间增加的频率要高于年轻患者。在每个队列中,大多数的不良事件都发生于出现术后残余肌松的患者。在年轻患者中,出现术后残余肌松的患者接受的罗库溴铵总量要高于未出现术后残余肌松的患者(60 vs 50mg);但是在老年患者中,出现术后残余肌松的患者与未出现术后残余肌松的患者间罗库溴铵的量不存在差异(均为50mg)。

最后研究人员得出结论:老年患者出现术后残余肌松以及相关不良预后的风险较年轻人增加。

原始出处:
Murphy GS, Szokol JW,et al.Residual Neuromuscular Block in the Elderly: Incidence and Clinical Implications.Anesthesiology. 2015 Oct 8.

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    2017-01-22 1e1f3a67m99(暂无匿称)

    学习到了

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=171911, encodeId=bff41e191134, content=学习到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKPeeEwPQq9TMKicgf58mJaQxKhBsHa2jnPrEYVBnZ8QD4tbiaUo3aNqM7EUfOzoPiaEELUb7VRE0HKA/132, createdBy=afcb2012691, createdName=1e1f3a67m99(暂无匿称), createdTime=Sun Jan 22 08:43:01 CST 2017, time=2017-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=127138, encodeId=701a12e1385a, content=文章不错,值得拜读, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Sep 15 07:35:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050502, encodeId=af3f205050214, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Thu May 05 18:42:00 CST 2016, time=2016-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=77457, encodeId=5b13e74575e, content=该现在常见,不完全是残余肌松剂吧。, beContent=null, objectType=article, channel=null, level=null, likeNumber=154, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160412/IMG570C62AB017373724.jpg, createdBy=f6b41705718, createdName=Wechat4343a314, createdTime=Mon Apr 11 21:36:00 CST 2016, time=2016-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=75693, encodeId=017ce5693fe, content=通过阅读了解到老年病人对非去极化肌松药与年轻人的代谢近20%的差到。, beContent=null, objectType=article, channel=null, level=null, likeNumber=186, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5ae41708835, createdName=1de9ac54m55(暂无匿称), createdTime=Tue Apr 05 22:58:00 CST 2016, time=2016-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47944, encodeId=add64e94478, content=很有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sat Dec 26 11:26:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47534, encodeId=fbcb4e53402, content=牛, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=c10c75714, createdName=zhuzhuba1, createdTime=Thu Dec 24 19:25:00 CST 2015, time=2015-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588205, encodeId=289315882056e, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Tue Oct 13 12:42:00 CST 2015, time=2015-10-13, status=1, ipAttribution=)]
    2016-09-15 1e10c84am36(暂无匿称)

    文章不错,值得拜读

    0

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    2016-04-11 Wechat4343a314

    该现在常见,不完全是残余肌松剂吧。

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=171911, encodeId=bff41e191134, content=学习到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKPeeEwPQq9TMKicgf58mJaQxKhBsHa2jnPrEYVBnZ8QD4tbiaUo3aNqM7EUfOzoPiaEELUb7VRE0HKA/132, createdBy=afcb2012691, createdName=1e1f3a67m99(暂无匿称), createdTime=Sun Jan 22 08:43:01 CST 2017, time=2017-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=127138, encodeId=701a12e1385a, content=文章不错,值得拜读, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Sep 15 07:35:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050502, encodeId=af3f205050214, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Thu May 05 18:42:00 CST 2016, time=2016-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=77457, encodeId=5b13e74575e, content=该现在常见,不完全是残余肌松剂吧。, beContent=null, objectType=article, channel=null, level=null, likeNumber=154, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160412/IMG570C62AB017373724.jpg, createdBy=f6b41705718, createdName=Wechat4343a314, createdTime=Mon Apr 11 21:36:00 CST 2016, time=2016-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=75693, encodeId=017ce5693fe, content=通过阅读了解到老年病人对非去极化肌松药与年轻人的代谢近20%的差到。, beContent=null, objectType=article, channel=null, level=null, likeNumber=186, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5ae41708835, createdName=1de9ac54m55(暂无匿称), createdTime=Tue Apr 05 22:58:00 CST 2016, time=2016-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47944, encodeId=add64e94478, content=很有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sat Dec 26 11:26:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47534, encodeId=fbcb4e53402, content=牛, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=c10c75714, createdName=zhuzhuba1, createdTime=Thu Dec 24 19:25:00 CST 2015, time=2015-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588205, encodeId=289315882056e, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Tue Oct 13 12:42:00 CST 2015, time=2015-10-13, status=1, ipAttribution=)]
    2016-04-05 1de9ac54m55(暂无匿称)

    通过阅读了解到老年病人对非去极化肌松药与年轻人的代谢近20%的差到。

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=171911, encodeId=bff41e191134, content=学习到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKPeeEwPQq9TMKicgf58mJaQxKhBsHa2jnPrEYVBnZ8QD4tbiaUo3aNqM7EUfOzoPiaEELUb7VRE0HKA/132, createdBy=afcb2012691, createdName=1e1f3a67m99(暂无匿称), createdTime=Sun Jan 22 08:43:01 CST 2017, time=2017-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=127138, encodeId=701a12e1385a, content=文章不错,值得拜读, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Sep 15 07:35:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050502, encodeId=af3f205050214, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Thu May 05 18:42:00 CST 2016, time=2016-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=77457, encodeId=5b13e74575e, content=该现在常见,不完全是残余肌松剂吧。, beContent=null, objectType=article, channel=null, level=null, likeNumber=154, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160412/IMG570C62AB017373724.jpg, createdBy=f6b41705718, createdName=Wechat4343a314, createdTime=Mon Apr 11 21:36:00 CST 2016, time=2016-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=75693, encodeId=017ce5693fe, content=通过阅读了解到老年病人对非去极化肌松药与年轻人的代谢近20%的差到。, beContent=null, objectType=article, channel=null, level=null, likeNumber=186, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5ae41708835, createdName=1de9ac54m55(暂无匿称), createdTime=Tue Apr 05 22:58:00 CST 2016, time=2016-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47944, encodeId=add64e94478, content=很有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sat Dec 26 11:26:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47534, encodeId=fbcb4e53402, content=牛, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=c10c75714, createdName=zhuzhuba1, createdTime=Thu Dec 24 19:25:00 CST 2015, time=2015-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588205, encodeId=289315882056e, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Tue Oct 13 12:42:00 CST 2015, time=2015-10-13, status=1, ipAttribution=)]
    2015-12-26 hixiaoluo

    很有道理

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=171911, encodeId=bff41e191134, content=学习到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKPeeEwPQq9TMKicgf58mJaQxKhBsHa2jnPrEYVBnZ8QD4tbiaUo3aNqM7EUfOzoPiaEELUb7VRE0HKA/132, createdBy=afcb2012691, createdName=1e1f3a67m99(暂无匿称), createdTime=Sun Jan 22 08:43:01 CST 2017, time=2017-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=127138, encodeId=701a12e1385a, content=文章不错,值得拜读, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Sep 15 07:35:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050502, encodeId=af3f205050214, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Thu May 05 18:42:00 CST 2016, time=2016-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=77457, encodeId=5b13e74575e, content=该现在常见,不完全是残余肌松剂吧。, beContent=null, objectType=article, channel=null, level=null, likeNumber=154, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160412/IMG570C62AB017373724.jpg, createdBy=f6b41705718, createdName=Wechat4343a314, createdTime=Mon Apr 11 21:36:00 CST 2016, time=2016-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=75693, encodeId=017ce5693fe, content=通过阅读了解到老年病人对非去极化肌松药与年轻人的代谢近20%的差到。, beContent=null, objectType=article, channel=null, level=null, likeNumber=186, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5ae41708835, createdName=1de9ac54m55(暂无匿称), createdTime=Tue Apr 05 22:58:00 CST 2016, time=2016-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47944, encodeId=add64e94478, content=很有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sat Dec 26 11:26:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47534, encodeId=fbcb4e53402, content=牛, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=c10c75714, createdName=zhuzhuba1, createdTime=Thu Dec 24 19:25:00 CST 2015, time=2015-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588205, encodeId=289315882056e, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Tue Oct 13 12:42:00 CST 2015, time=2015-10-13, status=1, ipAttribution=)]
    2015-12-24 zhuzhuba1

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=171911, encodeId=bff41e191134, content=学习到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKPeeEwPQq9TMKicgf58mJaQxKhBsHa2jnPrEYVBnZ8QD4tbiaUo3aNqM7EUfOzoPiaEELUb7VRE0HKA/132, createdBy=afcb2012691, createdName=1e1f3a67m99(暂无匿称), createdTime=Sun Jan 22 08:43:01 CST 2017, time=2017-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=127138, encodeId=701a12e1385a, content=文章不错,值得拜读, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Sep 15 07:35:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050502, encodeId=af3f205050214, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Thu May 05 18:42:00 CST 2016, time=2016-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=77457, encodeId=5b13e74575e, content=该现在常见,不完全是残余肌松剂吧。, beContent=null, objectType=article, channel=null, level=null, likeNumber=154, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160412/IMG570C62AB017373724.jpg, createdBy=f6b41705718, createdName=Wechat4343a314, createdTime=Mon Apr 11 21:36:00 CST 2016, time=2016-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=75693, encodeId=017ce5693fe, content=通过阅读了解到老年病人对非去极化肌松药与年轻人的代谢近20%的差到。, beContent=null, objectType=article, channel=null, level=null, likeNumber=186, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5ae41708835, createdName=1de9ac54m55(暂无匿称), createdTime=Tue Apr 05 22:58:00 CST 2016, time=2016-04-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47944, encodeId=add64e94478, content=很有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sat Dec 26 11:26:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=47534, encodeId=fbcb4e53402, content=牛, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=c10c75714, createdName=zhuzhuba1, createdTime=Thu Dec 24 19:25:00 CST 2015, time=2015-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1588205, encodeId=289315882056e, content=<a href='/topic/show?id=1cb8e014e0' target=_blank style='color:#2F92EE;'>#ESI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7014, encryptionId=1cb8e014e0, topicName=ESI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4f817593223, createdName=skhzy, createdTime=Tue Oct 13 12:42:00 CST 2015, time=2015-10-13, status=1, ipAttribution=)]
    2015-10-13 skhzy
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