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Stroke:步行速度与卒中发病率之间的关系

2020-04-18 MedSci原创 MedSci原创

在这项以人群为基础的队列研究中,64岁以上的参与者步行速度慢与较高的卒中风险有关。在初级保健或公共卫生临床咨询中增加自我报告步行速度这一指标可能是一个有用的卒中风险筛查工具。

中青年脑卒中发病率呈上升趋势。尽管如此,它在卒中人群中的关联仍未明确,而且预防策略也不能满足他们的需要。近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,这项研究旨在评估自我报告的步行速度和突发卒中之间的关系。

这项基于人群的前瞻性研究来自英国生物库的数据,共招募了363137名年龄在37岁至73岁之间参与者(52%为女性)。研究人员采用Cox比例风险模型调查了随访期间自我报告的步行速度与卒中发生率之间的关系。

在363137名参与者中,2705名(0.7%)参与者在6.1年(四分位间距为5.4-6.7)的平均随访期内发生了致命或非致命的卒中事件。慢速步行与卒中发生率的危险系数较高(风险比[HR]为1.45[95%CI为1.26-1.66];P<0.0001)。65岁以下人群的卒中发生率与步行速度无关。然而,在年龄≥65岁的参与者中,慢速步行与更高的卒中风险相关(HR为1.42[95%CI为1.17-1.72];P<0.0001)。中度(HR为1.28[95%CI为1.01-1.63];P=0.039)及以上(HR为1.29[95%CI为1.05-1.69];P=0.012)被剥夺程度的个体卒中风险较高,相比于被剥夺程度最轻的个体。同样,超重(HR为1.30[95%CI为1.04-1.63];P=0.019)和肥胖(HR为1.33[95%CI为1.09-1.63];P=0.004)个体发生卒中的风险更高,相比于正常体重的个体。

在这项以人群为基础的队列研究中,64岁以上的参与者步行速度慢与较高的卒中风险有关。在初级保健或公共卫生临床咨询中增加自我报告步行速度这一指标可能是一个有用的卒中风险筛查工具。

原始出处:

Sara Hayes.Broersen.et al.Association Between Walking Pace and Stroke Incidence Findings From the UK Biobank Prospective Cohort Study.stroke.2020.https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.028064

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    2020-04-19 一天没事干

    很好的学习机会

    0

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    2020-04-18 一天没事干

    很好的学习机会

    0

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    2020-04-18 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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    2020-04-18 飛歌

    学习了很有用不错

    0

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