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Stroke:急性脑卒中后血压波动越大 结局越糟糕!

2018-08-07 王淳 环球医学

2018年7月,发表于《Stroke》上的一项研究,表明了脑出血后血压变异性(BPV)的增加会加剧更差的结局。

2018年7月,发表于《Stroke》上的一项研究,表明了脑出血后血压变异性(BPV)的增加会加剧更差的结局。

背景&目的:BPV的增加与急性缺血性卒中后较差的结局相关,并且在脑出血后可能还有负面影响。研究者在ATACH-2(急性脑出血的降压治疗II)试验中试图考察BPV增加是否有害。

方法:研究者研究的主要结局指标是3个月随访的改良Rankin量表3~6分,次要结局指标是效用加权改良Rankin量表。使用急性期(住院后2~24 h)和亚急性期(2、3和7日)的收缩压,计算血压平均值和变异性。

结果:急性期纳入913名患者,亚急性期纳入877名。对于收缩期BPV的5种不同统计学检测指标均显示,急性期和亚急性期BPV增加和恶化的神经功能结局相关。但收缩压平均值未显示出这种关联。

结论:在ATACH-2的二次分析中,研究者发现收缩期BPV增加与恶化的长期神经功能结局相关。需要进行更多的研究,以找到能够早期识别预期BPV升高的患者的技术,并研究基于药物或方案的方法来最小化BPV。

原始出处

de Havenon A, et al. Increased Blood Pressure Variability Contributes to Worse Outcome After Intracerebral Hemorrhage: An Analysis of ATACH-2. Stroke. 2018 Jul 16. pii: STROKEAHA.118.022133. doi: 10.1161/STROKEAHA.118.022133.

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    2018-08-10 太阳系小猪

    学习了,谢谢分享,也就是脑出血后需要严格控制血压,控制到多少呢?

    0

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    2018-08-08 131****1460

    学习了受益匪浅

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2023336, encodeId=1f5420233369f, content=<a href='/topic/show?id=55d4889548b' target=_blank style='color:#2F92EE;'>#血压波动#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88954, encryptionId=55d4889548b, topicName=血压波动)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Wed Sep 19 00:09:00 CST 2018, time=2018-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1671347, encodeId=192816e13471b, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff7426824786, createdName=waiwai3039, createdTime=Fri Nov 02 06:09:00 CST 2018, time=2018-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337650, encodeId=956333e6508a, content=学习了,谢谢分享,也就是脑出血后需要严格控制血压,控制到多少呢?, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7e71713450, createdName=太阳系小猪, createdTime=Fri Aug 10 07:02:18 CST 2018, time=2018-08-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366957, encodeId=07c8136695e59, content=<a href='/topic/show?id=d0e0524218b' target=_blank style='color:#2F92EE;'>#急性脑卒中#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52421, encryptionId=d0e0524218b, topicName=急性脑卒中)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=856b247, createdName=songbq, createdTime=Thu Aug 09 09:09:00 CST 2018, time=2018-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337246, encodeId=569233e24637, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Aug 08 08:29:20 CST 2018, time=2018-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026121, encodeId=529a102612174, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Tue Aug 07 21:09:00 CST 2018, time=2018-08-07, status=1, ipAttribution=)]
    2018-08-07 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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