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Eur Heart J:工作时间越长 房颤风险越高

2017-09-29 安雅晶 环球医学

2017年9月,发表在《Eur Heart J》的一项由英国、芬兰、美国等国科学家进行的多队列研究表明,工作时间长为房颤的风险因素。

2017年9月,发表在《Eur Heart J》的一项由英国、芬兰、美国等国科学家进行的多队列研究表明,工作时间长为房颤的风险因素。

目的:研究表明,长时间工作的人,卒中风险增加,但是长时间工作与房颤(最常见的心律失常和卒中风险因素)之间的相关性未知。研究者考察了每周工作≥55小时和每周标准工作35~40小时的个体的房颤风险。

方法和结果:在这项来自于工作人群个体参与者数据的Meta分析(IPD-Work)联盟的回顾性多队列研究中,研究人群为85494名无房颤的男性和女性工作者(平均43.4岁)。于研究基线评估工作时长(1991~2004)。房颤发病的平均随访期为10年,使用心电图、医院记录、药品报销登记、死亡证明定义病例。研究者鉴别出1061例房颤新发病例(10年累积发病率为12.4/1000)。调整了年龄、性别和社会经济状态后,长时间工作比标准时长工作者的房颤风险高1.4倍(风险比,1.42;95% CI,1.13~1.80;P=0.003)。队列特异性效果评估间无显着的异质性(I2=0%,P=0.66),排除了基线患有或随访期发现冠心病或卒中的参与者后,该结果仍保持一致(N,2006;风险比,1.36;95% CI,1.05~1.76;P=0.0180)。潜在混杂因素,如肥胖、危险的饮酒、高血压等的调整对该相关性几乎无影响。

结论:长时间工作者比标准时长工作者更可能发生房颤。

原始出处:
Kivimki M, Nyberg ST, Batty GD,et al. Long working hours as a risk factor for atrial fibrillation: a multi-cohort study.Eur Heart J. 2017 Sep 7;38(34):2621-2628. doi: 10.1093/eurheartj/ehx324.

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    2017-10-01 zhaojie88
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    2017-10-01 slcumt
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    2017-09-29 清风拂面

    谢谢分享.学习了

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