Baidu
map

Stroke:颅内动脉狭窄及其与一般人群常规危险因素的关系

2019-07-23 xing.T MedSci原创

在这个以社区为基础的日本男性样本中,ICAS估计占25.2%,除高血压和年龄外,还与代谢危险因素有关。这些结果支持全面管理常规心血管危险因素对卒中预防的重要性。

很少有基于社区的研究报道用磁共振血管造影评估颅内动脉狭窄(ICAS)的患病率。近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,该研究旨在一般日本男性人群中使用磁共振血管造影确定ICAS的患病率,并探究ICAS与常规心血管危险因素之间的关联。 

2006年至2008年,研究人员随机招募并评估了亚临床动脉粥样硬化的志贺流行病学研究(基线,2012年至2015年)中来自日本滋贺县草津市的参与者;740名男性进行随访并接受1.5T脑磁共振血管造影检查。参与者被分类为无ICAS、轻度ICAS(1-50%)或严重ICAS(≥50%)。在排除有卒中病史的男性后,研究人员使用多变量logistic回归分析了709名男性,以评估常规心血管危险因素的独立关联,参考组为无ICAS组。 

参与者的平均年龄为68.0岁。轻度和重度ICAS的年龄标准化患病率分别为20.7%和4.5%(以2010年日本人口统计数据的人口为参考)。在同时调整常规心血管危险因素后,年龄、高血压糖尿病和血脂异常与严重ICAS的患病率较高有关。

在这个以社区为基础的日本男性样本中,ICAS估计占25.2%,除高血压和年龄外,还与代谢危险因素有关。这些结果支持全面管理常规心血管危险因素对卒中预防的重要性。 

原始出处:

Satoshi Shitara.et al.Intracranial Artery Stenosis and Its Association With Conventional Risk Factors in a General Population of Japanese Men.stroke.2019.https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.025964

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1661453, encodeId=afe81661453c0, content=<a href='/topic/show?id=5f32100380f3' target=_blank style='color:#2F92EE;'>#颅内动脉狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100380, encryptionId=5f32100380f3, topicName=颅内动脉狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c2a25292014, createdName=ms5236388012055669, createdTime=Wed Feb 19 23:22:00 CST 2020, time=2020-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370396, encodeId=bd873e039674, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Sun Jul 28 10:45:47 CST 2019, time=2019-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370346, encodeId=25d73e034611, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Sat Jul 27 10:39:37 CST 2019, time=2019-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370290, encodeId=9ed53e0290b1, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Fri Jul 26 11:37:07 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496914, encodeId=bec1149691473, content=<a href='/topic/show?id=217b33259df' target=_blank style='color:#2F92EE;'>#动脉狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33259, encryptionId=217b33259df, topicName=动脉狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4ae9287436, createdName=piaojinhua, createdTime=Thu Jul 25 00:22:00 CST 2019, time=2019-07-25, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1661453, encodeId=afe81661453c0, content=<a href='/topic/show?id=5f32100380f3' target=_blank style='color:#2F92EE;'>#颅内动脉狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100380, encryptionId=5f32100380f3, topicName=颅内动脉狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c2a25292014, createdName=ms5236388012055669, createdTime=Wed Feb 19 23:22:00 CST 2020, time=2020-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370396, encodeId=bd873e039674, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Sun Jul 28 10:45:47 CST 2019, time=2019-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370346, encodeId=25d73e034611, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Sat Jul 27 10:39:37 CST 2019, time=2019-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370290, encodeId=9ed53e0290b1, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Fri Jul 26 11:37:07 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496914, encodeId=bec1149691473, content=<a href='/topic/show?id=217b33259df' target=_blank style='color:#2F92EE;'>#动脉狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33259, encryptionId=217b33259df, topicName=动脉狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4ae9287436, createdName=piaojinhua, createdTime=Thu Jul 25 00:22:00 CST 2019, time=2019-07-25, status=1, ipAttribution=)]
    2019-07-28 一天没事干

    很好的学习机会

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1661453, encodeId=afe81661453c0, content=<a href='/topic/show?id=5f32100380f3' target=_blank style='color:#2F92EE;'>#颅内动脉狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100380, encryptionId=5f32100380f3, topicName=颅内动脉狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c2a25292014, createdName=ms5236388012055669, createdTime=Wed Feb 19 23:22:00 CST 2020, time=2020-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370396, encodeId=bd873e039674, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Sun Jul 28 10:45:47 CST 2019, time=2019-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370346, encodeId=25d73e034611, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Sat Jul 27 10:39:37 CST 2019, time=2019-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370290, encodeId=9ed53e0290b1, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Fri Jul 26 11:37:07 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496914, encodeId=bec1149691473, content=<a href='/topic/show?id=217b33259df' target=_blank style='color:#2F92EE;'>#动脉狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33259, encryptionId=217b33259df, topicName=动脉狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4ae9287436, createdName=piaojinhua, createdTime=Thu Jul 25 00:22:00 CST 2019, time=2019-07-25, status=1, ipAttribution=)]
    2019-07-27 一天没事干

    很好的学习机会

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1661453, encodeId=afe81661453c0, content=<a href='/topic/show?id=5f32100380f3' target=_blank style='color:#2F92EE;'>#颅内动脉狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100380, encryptionId=5f32100380f3, topicName=颅内动脉狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c2a25292014, createdName=ms5236388012055669, createdTime=Wed Feb 19 23:22:00 CST 2020, time=2020-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370396, encodeId=bd873e039674, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Sun Jul 28 10:45:47 CST 2019, time=2019-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370346, encodeId=25d73e034611, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Sat Jul 27 10:39:37 CST 2019, time=2019-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370290, encodeId=9ed53e0290b1, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Fri Jul 26 11:37:07 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496914, encodeId=bec1149691473, content=<a href='/topic/show?id=217b33259df' target=_blank style='color:#2F92EE;'>#动脉狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33259, encryptionId=217b33259df, topicName=动脉狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4ae9287436, createdName=piaojinhua, createdTime=Thu Jul 25 00:22:00 CST 2019, time=2019-07-25, status=1, ipAttribution=)]
    2019-07-26 一天没事干

    很好的学习机会

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1661453, encodeId=afe81661453c0, content=<a href='/topic/show?id=5f32100380f3' target=_blank style='color:#2F92EE;'>#颅内动脉狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100380, encryptionId=5f32100380f3, topicName=颅内动脉狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c2a25292014, createdName=ms5236388012055669, createdTime=Wed Feb 19 23:22:00 CST 2020, time=2020-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370396, encodeId=bd873e039674, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Sun Jul 28 10:45:47 CST 2019, time=2019-07-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370346, encodeId=25d73e034611, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Sat Jul 27 10:39:37 CST 2019, time=2019-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370290, encodeId=9ed53e0290b1, content=很好的学习机会, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/04/12/cd30eefc465f70dc4dad89bd57479781.jpg, createdBy=02be2318568, createdName=一天没事干, createdTime=Fri Jul 26 11:37:07 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1496914, encodeId=bec1149691473, content=<a href='/topic/show?id=217b33259df' target=_blank style='color:#2F92EE;'>#动脉狭窄#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33259, encryptionId=217b33259df, topicName=动脉狭窄)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4ae9287436, createdName=piaojinhua, createdTime=Thu Jul 25 00:22:00 CST 2019, time=2019-07-25, status=1, ipAttribution=)]

相关资讯

Neurology:高敏C反应蛋白水平可预测颅内动脉狭窄患者接受双联抗血小板治疗效果

研究认为颅内动脉狭窄伴无hsCRP水平升高患者接受双联抗血小板治疗效果更佳

AJNR:球囊颅内血管成形术的价值

SAMMPRIS研究发现内科治疗组30天卒中或死亡发生率为5.8%,而支架组为14.7%。因此,症状性颅内动脉狭窄的最佳治疗措施尚不清楚。很多专家一直探索是否某一些严重颅内动脉狭窄的患者能够从血管内治疗中获益。因为1年的卒中和死亡率高达12.2%,因此尚存在很大的空间来改善这些患者的管理,即使在SAMMPRIS研究内科治疗组。这样,对于处于卒中最高风险的患者,有人建议应该采取primary ang

Sci Rep:颅内外动脉狭窄与臂间血压差异相关

臂间血压(BP)的差异与缺血性卒中相关。不同的群体局部动脉粥样硬化,亚洲人更易受颅内动脉狭窄(ICAS)影响,而白人颅外动脉狭窄(ECAS)是更普遍的。研究者试图探讨中国人群中无脑卒中的高血压患者ICA及ECA与臂间血压差异的相关性。通过CT血管造影评估885名受试者的ICA及ECA。血管Profiler-1000装置同时测量双臂血压。在不断的研究中,ICAS均与年龄、男性、平均肱动脉SBP、糖尿

Stroke:升高的中性粒细胞和存在颅内动脉狭窄增加了复发性卒中的风险

由此可见,同时存在较高的中性粒细胞水平和ICAS与卒中复发风险增加相关,并且在已经患有轻微缺血性卒中或高风险短暂性脑缺血发作的患者中与复合不良结局事件相关。

Stroke:中性粒细胞升高和ICAS增加卒中复发风险

我国及世界范围内的卒中相关流行病学数据均表明短暂性脑缺血发作(TIA)与轻型卒中的发病率逐年上升,对于这样一个庞大患者群体,如何避免其进展为更为严重的致残性卒中,从而减轻整个家庭乃至国家的负担是一个艰巨难题。

PLoS One:颅内动脉狭窄的数量与卒中严重程度独立相关

目的:研究者旨在探讨颅内动脉狭窄数量(NSMIA),狭窄的程度及卒中危险因素与缺血性脑卒中的严重程度的相关性。方法:研究者对行全脑血管造影(DSA)确诊的缺血性脑卒中进行回顾性分析研究。采用美国国立卫生院卒中量表(NIHSS)评定卒中的严重程度。计数双侧颈内动脉和椎动脉狭窄的血管数目。结果: 从一个中心招募83例患者纳入研究。NSMIA与卒中的严重程度显著相关(皮尔森相关系数= 0.485,P<0

Baidu
map
Baidu
map
Baidu
map