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JACC:心血管循环生物标志物存在明显性别差异

2019-09-19 不详 MedSci原创

男女在蛋白质组学上的差异可能导致心血管疾病生物学信号存在性别差异。本研究的目的旨在探究心血管疾病发展过程中循环生物标志物的性别差异。本研究对7184名参与者(女性占54%,平均年龄49岁)进行了71种心血管生物标志物蛋白的检测。在71种生物标志物中,有61种存在性别差异,其中37种在女性中更高,24种在男性中更高。这种性别差异在绝经前期女性与男性中最明显,在绝经后没有接受激素治疗的女性中差异明显减

男女在蛋白质组学上的差异可能导致心血管疾病生物学信号存在性别差异。本研究的目的旨在探究心血管疾病发展过程中循环生物标志物的性别差异。

本研究对7184名参与者(女性占54%,平均年龄49岁)进行了71种心血管生物标志物蛋白的检测。在71种生物标志物中,有61种存在性别差异,其中37种在女性中更高,24种在男性中更高。这种性别差异在绝经前期女性与男性中最明显,在绝经后没有接受激素治疗的女性中差异明显减少。

研究结果显示,在白种人中,心血管生物标志物存在明显的性别差异,包括在炎症、肥胖、纤维化和血小板稳态等方面的差异。

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    2020-09-14 辣妈

    学习了

    0

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    2020-04-07 hbwxf
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  8. 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createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Thu Sep 19 13:18:35 CST 2019, time=2019-09-19, status=1, ipAttribution=)]
    2019-09-19 天地飞扬

    学习

    0

  9. 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    2019-09-19 1ddf0692m34(暂无匿称)

    学习了,谢谢分享

    0

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