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EUR HEART J:近30万人的研究告诉你肥胖和心血管疾病的关系

2018-03-18 海北 MedSci原创

现有的关于体重指数(BMI)与心血管疾病(CVD)风险相关性的数据,特别是那些低BMI类别的数据,是相互矛盾的。为此,来自格拉斯哥大学的研究人员进行了一项研究,目的是检查在健康个体中,身体组成(通过五种不同测量评估)与CVD结果的关联。

现有的关于体重指数(BMI)与心血管疾病(CVD)风险相关性的数据,特别是那些低BMI类别的数据,是相互矛盾的。为此,来自格拉斯哥大学的研究人员进行了一项研究,目的是检查在健康个体中,身体组成(通过五种不同测量评估)与CVD结果的关联。

研究人员招募了来自英国生物库的296535名参与者(57.8%为女性),其为欧洲白人后裔,基线时没有心血管疾病。

研究人员发现,低体重指数(≤18.5kg m-2)与心血管疾病发病率较高有关,而BMI22-23 kg / m2的人群的CVD风险最低,之后,随着BMI增加,CVD风险也增加。但是,当研究人员排除并发症患者时,这种J型关联在亚组分析中显着减弱。

相反,其余肥胖指标的联系更为线性:女性腰围的SD增加1的风险比为1.16 [95%可信区间(CI1.13-1.19],而男性为1.1095CI 1.08-1.13),腰臀比,腰高比和体脂百分比的风险比类似。

因此,在中年男性和女性中,肥胖的增加与心血管健康有着不利联系。由于并发症的存在,与其他肥胖指标相比,BMI与心血管疾病的关联似乎更容易混淆。因此,关于脂肪对心血管疾病风险的保护性影响的误解都应该受到质疑。


原始出处:

Stamatina Iliodromiti et al. The impact of confounding on the associations of different adiposity measures with the incidence of cardiovascular disease: a cohort study of 296 535 adults of white European descentEuropean Heart Journal, 2018; DOI: 10.1093/eurheartj/ehy057


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    2018-03-26 大爰

    学习了谢谢分享!!

    0

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    2018-03-20 zhaojie88
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    2018-03-20 slcumt
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    2018-03-19 和平max

    学习了.该开始减肥了

    0

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    2018-03-18 秀红

    学习了

    0

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    2018-03-18 戒馋,懒,贪

    谢谢分享学习了

    0

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