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T12椎体压缩性骨折经皮椎体成形术后椎管内硬膜外血肿1例

2018-12-18 白有海 实用骨科杂志

61岁女性患者,以“外伤后致腰背部疼痛活动受限1d”为主诉就诊。患者1d前在家不慎摔倒,臀部着地致伤腰背部,当时即感腰背部疼痛,四肢皮肤感觉麻木、尚能站立行走。在家服药休息,疗效差,疼痛加重来院。查体:T12椎体处后凸畸形,椎旁肌痉挛,胸椎因疼痛活动受限,T12椎体压痛(+),叩击痛(+)。左右侧髂腰肌、股四头肌、小腿三头肌、胫前肌、足足母伸肌Ⅴ级。颈部、躯干、四肢浅感觉、深感觉正常。股四头肌反射

病例资料

61岁女性患者,以“外伤后致腰背部疼痛活动受限1d”为主诉就诊。患者1d前在家不慎摔倒,臀部着地致伤腰背部,当时即感腰背部疼痛,四肢皮肤感觉麻木、尚能站立行走。在家服药休息,疗效差,疼痛加重来院。查体:T12椎体处后凸畸形,椎旁肌痉挛,胸椎因疼痛活动受限,T12椎体压痛(+),叩击痛(+)。左右侧髂腰肌、股四头肌、小腿三头肌、胫前肌、足足母伸肌Ⅴ级。颈部、躯干、四肢浅感觉、深感觉正常。股四头肌反射(++),膝反射(++),踝反射(++)。Babinski征(-),Kerning征(-)。直腿抬高试验(-),加强试验(-)。

胸椎X线示T12椎体呈楔形改变,压缩3/5(见图1);CT示T12椎体压缩性骨折(见图2);MRI示T12椎体压缩骨折并骨髓水肿(见图3)。患者既往有高血压病史多年,一直口服药物治疗,入院血压140/70mmHg。诊断:T12椎体压缩性骨折,高血压2级。平卧硬板床,给予消肿、活血、抗凝等治疗。白细胞计数4.53×109/L,红细胞计数5.9×109/L,血红蛋白179g/L,血小板76×1012/L。凝血功能、肝肾功能检查基本正常。复查血小板87×1012/L。入院第8天局部麻醉下行经皮椎体成形术。取俯卧过伸位,C型臂X线机透视确定椎弓根位置,消毒铺巾,2%利多卡因在穿刺点皮肤向椎弓根方向全层浸润麻醉;选择椎弓根外缘的体表投影外侧1CM为穿刺点;双向透视,将穿刺针置入椎体前1/3交界处,拔出穿刺针内的内芯,骨水泥缓慢填塞,直至填塞均匀充分。





将骨水泥推注杆完全拔出,纱布包扎。手术顺利,麻醉效果满意。下肢肌力及感觉正常,安返病房。给予消肿、活血、抗凝预防深静脉血栓等治疗。术后12h患者感腰部疼痛、左下肢麻木,给予止痛处理。术后26h感左下肢疼痛麻木、大小便正常。查体:T12椎体处恢复正常,椎旁肌无痉挛,胸椎活动不受限,T12椎体压痛(-),叩击痛(+)。肌力检查:左侧髂腰肌、股四头肌、小腿三头肌、胫前肌、足足母伸肌Ⅲ级,右侧肌髂腰肌、股四头肌Ⅳ级,右侧小腿三头肌、胫前肌、足足母伸肌Ⅴ级。左下肢浅感觉异常、深感觉正常。左下肢腱反射减弱不明显。复查X线片T12椎体见骨水泥痕迹,椎体高度恢复可(见图4)。胸椎MRIT12椎体见骨水泥痕迹,T10~L2椎管内囊性改变,考虑出血(见图5)。

结合症状、体征及核磁共振检查。诊断T12压缩性骨折椎体成形术后椎管内硬膜外血肿。给予输血浆400mL,营养神经、脱水、激素冲击疗法,严密观察病情变化,做好急诊手术准备。保守治疗期间,患者病情逐渐好转。复查血小板127×1012/L。术后第6天左下肢无疼痛,左股前侧仍感麻木。左下肢肌力Ⅳ级,右侧肌力Ⅴ级。能行走上厕所。复查胸椎MRI示椎管内出血明显吸收(见图6)。患者拒绝继续治疗,签字出院。术后30d电话回访,患者诉左下肢无疼痛,感左股前侧麻木好转,行走正常。患者拒绝来院检查复诊。

讨论

经皮椎体成形术广泛应用于老年骨质疏松性脊柱骨折,但作为一种有创手术,仍有一定的手术风险,出现椎管内硬膜外血肿罕见。椎管内硬膜外血肿多以急性为主,临床少见,文献以病案报道为主。病因是凝血功能障碍、外伤、血管畸形及自发性出血、硬膜外麻醉、椎管内手术等。表现为脊髓压迫症状,严重时瘫痪,因此早期诊断非常重要。

诊断除临床表现外,MRI是重要方法,能显示和确认脊髓压迫,还能排外脊柱其他病变。治疗多以急诊手术为主。李国忠等认为有明显脊髓压迫症状者一经确诊,应立即手术治疗,行椎板减压,血肿清除术。韩芸峰等认为对于下列情况可考虑保守治疗:a)患者神经功能受损较轻,AISA分级或Frank分级为E级;b)AISA分级或Frank分级为C/D级,但神经功能逐渐恢复者;c)发病后早期神经功能出现恢复者。血肿吸收或消失是保守治疗的前提。

尹升吉等认为对于起病缓慢,脊髓功能损伤较轻者可采取保守治疗。分析本例形成血肿的可能原因:由于椎体处有丰富的无静脉瓣的静脉丛,麻醉或手术穿刺时误入硬膜外腔损伤小静脉出血,患者有高血压、术前血小板低,术前应用抗凝药导致凝血困难,最后形成血肿压迫脊髓。患者神经功能受损较轻,MRI表现血肿位于T10~L2椎管内背侧,大而弥散,根据MRI表现考虑血肿在硬膜外间隙向上下弥散,减轻了对脊髓神经压迫。由于患者神经症状较轻,同时术后26h内神经功能加重趋势不明显,我们在做好急诊手术准备的前提下采取保守治疗。给予输血浆、大剂量激素、脱水、营养神经治疗观察,神经功能逐渐恢复,血肿明显吸收。分析出现该并发症原因,主要是术前未重视患者基础病高血压和低血小板,应引以为戒。

原始出处:

白有海. T12椎体压缩性骨折经皮椎体成形术后椎管内硬膜外血肿1例[J]. 实用骨科杂志, 2018, 24(11): 1047-1048.

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  4. 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createdTime=Thu Dec 20 06:06:00 CST 2018, time=2018-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1394940, encodeId=60591394940a2, content=<a href='/topic/show?id=be548989e09' target=_blank style='color:#2F92EE;'>#血肿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89897, encryptionId=be548989e09, topicName=血肿)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85df2500173, createdName=654699882_84926986, createdTime=Thu Dec 20 06:06:00 CST 2018, time=2018-12-20, status=1, ipAttribution=)]
    2019-03-15 gds2009
  5. 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  6. 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encodeId=b24b1e063446e, content=<a href='/topic/show?id=8fea628369c' target=_blank style='color:#2F92EE;'>#椎体压缩性骨折#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62836, encryptionId=8fea628369c, topicName=椎体压缩性骨折)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e68f31222224, createdName=12498484m56(暂无昵称), createdTime=Tue Oct 29 16:06:00 CST 2019, time=2019-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366853, encodeId=354f1366853f7, content=<a href='/topic/show?id=708a6283509' target=_blank style='color:#2F92EE;'>#椎体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62835, encryptionId=708a6283509, topicName=椎体)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=930e243, createdName=dingxiaobo, createdTime=Thu Dec 20 06:06:00 CST 2018, time=2018-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1394940, encodeId=60591394940a2, content=<a href='/topic/show?id=be548989e09' target=_blank style='color:#2F92EE;'>#血肿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89897, encryptionId=be548989e09, topicName=血肿)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85df2500173, createdName=654699882_84926986, createdTime=Thu Dec 20 06:06:00 CST 2018, time=2018-12-20, status=1, ipAttribution=)]
    2019-08-26 bugit
  7. [GetPortalCommentsPageByObjectIdResponse(id=2004706, encodeId=bfb62004e062b, content=<a href='/topic/show?id=4e8a5400816' target=_blank style='color:#2F92EE;'>#成形术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54008, encryptionId=4e8a5400816, topicName=成形术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7fb6449, createdName=ZGMFX24A, createdTime=Sat Sep 21 02:06:00 CST 2019, time=2019-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1709490, encodeId=74291e09490b1, content=<a href='/topic/show?id=266162841b4' target=_blank style='color:#2F92EE;'>#椎体成形术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62841, encryptionId=266162841b4, topicName=椎体成形术)], attachment=null, authenticateStatus=null, createdAvatar=null, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62880, encryptionId=de3362880f1, topicName=椎管内)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae6d29130493, createdName=bugit, createdTime=Mon Aug 26 12:06:00 CST 2019, time=2019-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1937155, encodeId=b18d193e15517, content=<a href='/topic/show?id=c06ae363256' target=_blank style='color:#2F92EE;'>#硬膜外#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73632, encryptionId=c06ae363256, topicName=硬膜外)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Sun May 26 19:06:00 CST 2019, time=2019-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706344, 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createdTime=Thu Dec 20 06:06:00 CST 2018, time=2018-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1394940, encodeId=60591394940a2, content=<a href='/topic/show?id=be548989e09' target=_blank style='color:#2F92EE;'>#血肿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89897, encryptionId=be548989e09, topicName=血肿)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85df2500173, createdName=654699882_84926986, createdTime=Thu Dec 20 06:06:00 CST 2018, time=2018-12-20, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=2004706, encodeId=bfb62004e062b, content=<a href='/topic/show?id=4e8a5400816' target=_blank style='color:#2F92EE;'>#成形术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54008, encryptionId=4e8a5400816, topicName=成形术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7fb6449, createdName=ZGMFX24A, createdTime=Sat Sep 21 02:06:00 CST 2019, time=2019-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1709490, encodeId=74291e09490b1, content=<a href='/topic/show?id=266162841b4' target=_blank style='color:#2F92EE;'>#椎体成形术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62841, encryptionId=266162841b4, topicName=椎体成形术)], attachment=null, authenticateStatus=null, createdAvatar=null, 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  9. [GetPortalCommentsPageByObjectIdResponse(id=2004706, encodeId=bfb62004e062b, content=<a href='/topic/show?id=4e8a5400816' target=_blank style='color:#2F92EE;'>#成形术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54008, encryptionId=4e8a5400816, topicName=成形术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7fb6449, createdName=ZGMFX24A, createdTime=Sat Sep 21 02:06:00 CST 2019, time=2019-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1709490, encodeId=74291e09490b1, content=<a href='/topic/show?id=266162841b4' target=_blank style='color:#2F92EE;'>#椎体成形术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62841, encryptionId=266162841b4, topicName=椎体成形术)], attachment=null, authenticateStatus=null, createdAvatar=null, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62880, encryptionId=de3362880f1, topicName=椎管内)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae6d29130493, createdName=bugit, createdTime=Mon Aug 26 12:06:00 CST 2019, time=2019-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1937155, encodeId=b18d193e15517, content=<a href='/topic/show?id=c06ae363256' target=_blank style='color:#2F92EE;'>#硬膜外#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73632, encryptionId=c06ae363256, topicName=硬膜外)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Sun May 26 19:06:00 CST 2019, time=2019-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706344, encodeId=b24b1e063446e, content=<a href='/topic/show?id=8fea628369c' target=_blank style='color:#2F92EE;'>#椎体压缩性骨折#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62836, encryptionId=8fea628369c, topicName=椎体压缩性骨折)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e68f31222224, createdName=12498484m56(暂无昵称), createdTime=Tue Oct 29 16:06:00 CST 2019, time=2019-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366853, encodeId=354f1366853f7, content=<a href='/topic/show?id=708a6283509' target=_blank style='color:#2F92EE;'>#椎体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62835, encryptionId=708a6283509, topicName=椎体)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=930e243, createdName=dingxiaobo, createdTime=Thu Dec 20 06:06:00 CST 2018, time=2018-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1394940, encodeId=60591394940a2, content=<a href='/topic/show?id=be548989e09' target=_blank style='color:#2F92EE;'>#血肿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89897, encryptionId=be548989e09, topicName=血肿)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85df2500173, createdName=654699882_84926986, createdTime=Thu Dec 20 06:06:00 CST 2018, time=2018-12-20, status=1, ipAttribution=)]
    2018-12-20 dingxiaobo
  10. 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createdBy=33fa31715680, createdName=HinsMax, createdTime=Thu Apr 11 06:06:00 CST 2019, time=2019-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1701086, encodeId=4ae31e010869b, content=<a href='/topic/show?id=130de3640ce' target=_blank style='color:#2F92EE;'>#硬膜外血肿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73640, encryptionId=130de3640ce, topicName=硬膜外血肿)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=396b30327016, createdName=zhs3892, createdTime=Fri Mar 01 08:06:00 CST 2019, time=2019-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1795243, encodeId=e58d1e952437c, content=<a href='/topic/show?id=91ee1e03868' target=_blank style='color:#2F92EE;'>#T12椎体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17038, encryptionId=91ee1e03868, topicName=T12椎体)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f612331, createdName=gds2009, createdTime=Fri Mar 15 16:06:00 CST 2019, time=2019-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1724250, encodeId=dc2a1e24250f1, content=<a href='/topic/show?id=71c1628e901' target=_blank style='color:#2F92EE;'>#椎管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62879, encryptionId=71c1628e901, topicName=椎管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7d4e33593434, createdName=caobinglei8090, createdTime=Fri Jan 04 16:06:00 CST 2019, time=2019-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1690776, encodeId=faaa1690e7663, content=<a href='/topic/show?id=de3362880f1' target=_blank style='color:#2F92EE;'>#椎管内#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62880, encryptionId=de3362880f1, topicName=椎管内)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae6d29130493, createdName=bugit, createdTime=Mon Aug 26 12:06:00 CST 2019, time=2019-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1937155, encodeId=b18d193e15517, content=<a href='/topic/show?id=c06ae363256' target=_blank style='color:#2F92EE;'>#硬膜外#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73632, encryptionId=c06ae363256, topicName=硬膜外)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Sun May 26 19:06:00 CST 2019, time=2019-05-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1706344, encodeId=b24b1e063446e, content=<a href='/topic/show?id=8fea628369c' target=_blank style='color:#2F92EE;'>#椎体压缩性骨折#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62836, encryptionId=8fea628369c, topicName=椎体压缩性骨折)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e68f31222224, createdName=12498484m56(暂无昵称), createdTime=Tue Oct 29 16:06:00 CST 2019, time=2019-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366853, encodeId=354f1366853f7, content=<a href='/topic/show?id=708a6283509' target=_blank style='color:#2F92EE;'>#椎体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62835, encryptionId=708a6283509, topicName=椎体)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=930e243, createdName=dingxiaobo, createdTime=Thu Dec 20 06:06:00 CST 2018, time=2018-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1394940, encodeId=60591394940a2, content=<a href='/topic/show?id=be548989e09' target=_blank style='color:#2F92EE;'>#血肿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89897, encryptionId=be548989e09, topicName=血肿)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=85df2500173, createdName=654699882_84926986, createdTime=Thu Dec 20 06:06:00 CST 2018, time=2018-12-20, status=1, ipAttribution=)]
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