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Maturitas:腰臀比预测绝经后女性亚临床动脉粥样硬化更佳

2015-02-16 高晓方 医学论坛网

韩国一项研究首次表明了在绝经后女性中,与体质指数(BMI)和腰围相比,腰臀比(WHR)为更好的亚临床动脉粥样硬化的预测因子。论文2月2日在线发表于《更年期》(Maturitas)杂志。 此项研究分别纳入209例绝经前女性和233例绝经后女性,排除了有心血管疾病史、恶性肿瘤或炎症性疾病以及正在服用抗炎药或激素替代治疗药的女性。并依据颈动脉内中膜厚度(CIMT)和臂踝脉搏波传导速度(ba

韩国一项研究首次表明了在绝经后女性中,与体质指数(BMI)和腰围相比,腰臀比(WHR)为更好的亚临床动脉粥样硬化的预测因子。论文2月2日在线发表于《更年期》(Maturitas)杂志。


此项研究分别纳入209例绝经前女性和233例绝经后女性,排除了有心血管疾病史、恶性肿瘤或炎症性疾病以及正在服用抗炎药或激素替代治疗药的女性。并依据颈动脉内中膜厚度(CIMT)和臂踝脉搏波传导速度(baPWV)评估潜在亚临床动脉粥样硬化。测定腰围、腰臀比和BMI等人体测量学指标。

结果显示,绝经前和绝经后女性的基线年龄分别为41和57岁,BMI分别为21.8和23,平均腰臀比分别为0.8和0.9(P<0.001)。绝经前、后女性的CMIT和baPWV亦存在差异(P<0.001),绝经前女性的平均CMIT和平均baPWV分别为0.6 mm 和11.5 m/s,绝经后女性的分别为0.7 mm 和13.4 m/s。

在绝经前女性中,所有人体测量学指标均均与CMIT和baPWV呈正相关性;在绝经后女性中,仅腰臀比与baPWV呈正相关性,腰围和腰臀比则与CIMT呈正相关性。

研究者们还发现,颈动脉粥样硬化(CIMT >0.9 mm)女性数量在绝经前、后女性中也有差异,分别为9例和67例。

原始出处:

Lee HJ1, Hwang SY2, Hong HC1, Ryu JY1, Seo JA1, Kim SG1, Kim NH1, Choi DS1, Baik SH1, Choi KM1, Yoo HJ3.Waist-to-hip ratio is better at predicting subclinical atherosclerosis than body mass index and waist circumference in postmenopausal women.Maturitas. 2015 Jan 12. pii: S0378-5122(14)00405-8. doi: 10.1016/j.maturitas.2014.12.015. [Epub ahead of print]

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createdTime=Wed Feb 18 00:05:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1526605, encodeId=cb12152660595, content=<a href='/topic/show?id=2fe6e88863a' target=_blank style='color:#2F92EE;'>#绝经后女性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78886, encryptionId=2fe6e88863a, topicName=绝经后女性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b55511745984, createdName=chenhongpeng, createdTime=Wed Feb 18 00:05:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631488, encodeId=977f163148827, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Wed Feb 18 00:05:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16163, encodeId=78e3161639b, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da6b7222, createdName=chinayinhan, createdTime=Tue Feb 17 00:47:00 CST 2015, time=2015-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15956, encodeId=48b6159565d, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:18:00 CST 2015, time=2015-02-16, status=1, ipAttribution=)]
    2015-02-28 慧读

    有价值

    0

  5. 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createdTime=Wed Feb 18 00:05:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1526605, encodeId=cb12152660595, content=<a href='/topic/show?id=2fe6e88863a' target=_blank style='color:#2F92EE;'>#绝经后女性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78886, encryptionId=2fe6e88863a, topicName=绝经后女性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b55511745984, createdName=chenhongpeng, createdTime=Wed Feb 18 00:05:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631488, encodeId=977f163148827, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Wed Feb 18 00:05:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16163, encodeId=78e3161639b, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da6b7222, createdName=chinayinhan, createdTime=Tue Feb 17 00:47:00 CST 2015, time=2015-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15956, encodeId=48b6159565d, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:18:00 CST 2015, time=2015-02-16, status=1, ipAttribution=)]
    2015-02-18 xiaotian628

    0

  6. 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topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Wed Feb 18 00:05:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16163, encodeId=78e3161639b, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da6b7222, createdName=chinayinhan, createdTime=Tue Feb 17 00:47:00 CST 2015, time=2015-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15956, encodeId=48b6159565d, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:18:00 CST 2015, time=2015-02-16, status=1, ipAttribution=)]
  7. 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time=2015-02-16, status=1, ipAttribution=)]
  8. 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createdTime=Wed Feb 18 00:05:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1526605, encodeId=cb12152660595, content=<a href='/topic/show?id=2fe6e88863a' target=_blank style='color:#2F92EE;'>#绝经后女性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78886, encryptionId=2fe6e88863a, topicName=绝经后女性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b55511745984, createdName=chenhongpeng, createdTime=Wed Feb 18 00:05:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631488, encodeId=977f163148827, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Wed Feb 18 00:05:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16163, encodeId=78e3161639b, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da6b7222, createdName=chinayinhan, createdTime=Tue Feb 17 00:47:00 CST 2015, time=2015-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15956, encodeId=48b6159565d, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:18:00 CST 2015, time=2015-02-16, status=1, ipAttribution=)]
    2015-02-18 zxxiang
  9. 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createdBy=7f401615413, createdName=慧读, createdTime=Sat Feb 28 12:14:00 CST 2015, time=2015-02-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16433, encodeId=2eba16433a0, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=xiaotian628, createdTime=Wed Feb 18 22:29:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1257010, encodeId=a3ce125e0109c, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Wed Feb 18 00:05:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1526605, encodeId=cb12152660595, content=<a href='/topic/show?id=2fe6e88863a' target=_blank style='color:#2F92EE;'>#绝经后女性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78886, encryptionId=2fe6e88863a, topicName=绝经后女性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b55511745984, createdName=chenhongpeng, createdTime=Wed Feb 18 00:05:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631488, encodeId=977f163148827, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Wed Feb 18 00:05:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16163, encodeId=78e3161639b, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da6b7222, createdName=chinayinhan, createdTime=Tue Feb 17 00:47:00 CST 2015, time=2015-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15956, encodeId=48b6159565d, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cce01615276, createdName=Johnny1989, createdTime=Mon Feb 16 15:18:00 CST 2015, time=2015-02-16, status=1, ipAttribution=)]
    2015-02-17 chinayinhan

    已阅

    0

  10. 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time=2015-02-16, status=1, ipAttribution=)]
    2015-02-16 Johnny1989

    已阅

    0

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