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BMJ:儿童及青少年对家庭成员新冠肺炎感染风险的影响

2021-03-21 MedSci原创 MedSci原创

与英国首轮新冠肺炎疫情相比,次轮疫情中,儿童及青少年对新冠肺炎传播起到了助推作用,导致家庭成员感染及住院风险增加

充分的证据表明,儿童及青少年对SARS-Cov-2感染的易感性较低,即使感染,导致严重疾病的风险也较低。目前儿童和青少年在新冠肺炎传播中的作用尚不确定,而对其他呼吸道感染(如流感)的建模表明,儿童是流行病初期传播的主要驱动力,部分原因是社会接触频率高。相比之下,积累的证据表明,儿童及青少年,特别是低龄儿童,由于较低的易感性和可能较低的感染性,其对新冠肺炎的传播能力可能低于成年人。
近日研究人员考察了在英国首轮及次轮新冠肺炎疫情期间,是否与儿童一起生活,对成年人群新冠肺炎感染风险的影响
本次研究为基于人口的队列研究,收集2020年2-8月以及9-12月期间,英国住院及急诊记录,研究的主要终点成人新冠肺炎感染、住院、急诊以及死亡风险。
 
在首轮疫情期间,9334392名65岁以下成年参与者中,未发现家庭中儿童对成人新冠肺炎感染、住院、急诊以及死亡风险有影响。在第二轮疫情期间,对于65岁以下成年参与者中,家庭中存在儿童导致新冠肺炎感染风险增加,其严重程度与儿童年龄相关:对于0-11岁儿童,其感染风险为1.06;12-18岁儿童为1.22。家庭中存在儿童导致成人新冠肺炎住院风险增加:0-11岁儿童,成人新冠肺炎住院风险为1.18,12-18岁为1.26。家庭中有0-11岁儿童,其家庭成年人因新冠肺炎或非新冠肺炎因素的死亡风险降低。在第二波疫情期间,家庭中有0-11岁儿童,其家庭成人中感染新冠肺炎的绝对风险增加,每10000人口感染人数增加40-60例;住院绝对风险增加,每10000人口住院人数增加1-5例。对于与12-18岁青少年一起居住的家庭,每10000人口感染人数增加160-190例,住院人数增加2-6例
研究发现,与英国首轮新冠肺炎疫情相比,次轮疫情中,儿童及青少年对新冠肺炎传播起到了助推作用,导致家庭成员感染及住院风险增加
 
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    2022-03-04 gaoxiaoe
  2. [GetPortalCommentsPageByObjectIdResponse(id=1849209, encodeId=8a4118492093b, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Mar 04 04:15:29 CST 2022, time=2022-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808773, encodeId=de021808e73c1, content=<a href='/topic/show?id=6d52821e35a' target=_blank style='color:#2F92EE;'>#肺炎感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82173, encryptionId=6d52821e35a, topicName=肺炎感染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5d7367, createdName=zhwj, createdTime=Thu Aug 19 12:15:29 CST 2021, time=2021-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=950152, encodeId=8752950152f1, content=话题有意义,但信息较少, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27235472050, createdName=ms5000001128139663, createdTime=Mon Mar 22 19:16:49 CST 2021, time=2021-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=949927, encodeId=62e894992efb, content=好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210321/b1a039d96bff444a9ca790f50674a4ee/816f3e2a7ba4460dbf430fc052a7d56d.jpg, createdBy=fddf5328558, createdName=148c43ebm02暂无昵称, createdTime=Sun Mar 21 17:03:09 CST 2021, time=2021-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1029262, encodeId=db2c102926200, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Mar 21 13:15:29 CST 2021, time=2021-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=949870, encodeId=87679498e040, content=很有帮助, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210321/f6b82837963d4f37862be9788dbdbad8/a979c36ab4cb4023a02397ef07bd4b30.jpg, createdBy=39b75471610, createdName=ms1000000840288050, createdTime=Sun Mar 21 11:36:38 CST 2021, time=2021-03-21, status=1, ipAttribution=)]
    2021-08-19 zhwj
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    2021-03-22 ms5000001128139663

    话题有意义,但信息较少

    0

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    2021-03-21 148c43ebm02暂无昵称

    好文章

    0

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    2021-03-21 公卫新人

    新冠肺炎,疫情何时才能消失

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1849209, encodeId=8a4118492093b, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Mar 04 04:15:29 CST 2022, time=2022-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808773, encodeId=de021808e73c1, content=<a href='/topic/show?id=6d52821e35a' target=_blank style='color:#2F92EE;'>#肺炎感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82173, encryptionId=6d52821e35a, topicName=肺炎感染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5d7367, createdName=zhwj, createdTime=Thu Aug 19 12:15:29 CST 2021, time=2021-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=950152, encodeId=8752950152f1, content=话题有意义,但信息较少, beContent=null, objectType=article, channel=null, level=null, likeNumber=129, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27235472050, createdName=ms5000001128139663, createdTime=Mon Mar 22 19:16:49 CST 2021, time=2021-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=949927, encodeId=62e894992efb, content=好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210321/b1a039d96bff444a9ca790f50674a4ee/816f3e2a7ba4460dbf430fc052a7d56d.jpg, createdBy=fddf5328558, createdName=148c43ebm02暂无昵称, createdTime=Sun Mar 21 17:03:09 CST 2021, time=2021-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1029262, encodeId=db2c102926200, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Mar 21 13:15:29 CST 2021, time=2021-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=949870, encodeId=87679498e040, content=很有帮助, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210321/f6b82837963d4f37862be9788dbdbad8/a979c36ab4cb4023a02397ef07bd4b30.jpg, createdBy=39b75471610, createdName=ms1000000840288050, createdTime=Sun Mar 21 11:36:38 CST 2021, time=2021-03-21, status=1, ipAttribution=)]
    2021-03-21 ms1000000840288050

    很有帮助

    0

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