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J Periodontal Implant Sci:椅旁唾液aMMP-8的检查结果与接受SPT的患者牙周风险评估的常用参数无关

2018-09-12 MedSci MedSci原创

本项回顾性横断面研究旨在评估椅旁检测(POC)唾液中活性基质金属蛋白酶8(aMMP-8)是否与患者接受牙周治疗(SPT)的牙周风险评估参数相关。 研究共纳入125名接受常规SPT的患者。纳入标准:慢性牙周炎的诊断,至少1次非手术牙周治疗(洁治和根面平整),遵循常规SPT(每年至少一次),至少剩余6个牙齿,同时获取检测临床和aMMP-8的检测结果。除了全身忆因素(如吸烟和糖尿病),记录口腔卫生

本项回顾性横断面研究旨在评估椅旁检测(POC)唾液中活性基质金属蛋白酶8(aMMP-8)是否与患者接受牙周治疗(SPT)的牙周风险评估参数相关。

研究共纳入125名接受常规SPT的患者。纳入标准:慢性牙周炎的诊断,至少1次非手术牙周治疗(洁治和根面平整),遵循常规SPT(每年至少一次),至少剩余6个牙齿,同时获取检测临床和aMMP-8的检测结果。除了全身忆因素(如吸烟和糖尿病),记录口腔卫生指数(改良龈沟出血指数[mSBI]和斑块指数),探查深度,探查出血,牙齿情况(龋齿数,缺失牙和充填牙齿。使用商业POC测试系统(Periomarker,Hager&Werken,Duisburg,Germany)检测唾液中aMMP-8的水平。使用t检验,Mann-Whitney U检验,Fisher精确检验和χ2检验进行统计学分析(P <0.05)。

结果显示,只有mSBI与阳性唾液aMMP-8的水平显著相关(aMMP-8阳性:27.8%±20.9%VS. aMMP-8阴性:18.0%±14.5%; P = 0.017)。aMMP-8与吸烟、糖尿病、牙周参数或与维持间隔相关的参数之间未发现明显相关性(P> 0.05)。

综上所述,该研究结果表明,椅旁唾液aMMP-8的检查结果与接受SPT的患者牙周风险评估的常用参数无关。POC唾液aMMP-8检测在SPT期间的风险评估和维持间隔调整中的诊断益处仍不清楚。

原始出处:

Schmalz G, Kummer MK, et al., Association of chairside salivary aMMP-8 findings with periodontal risk assessment parameters in patients receiving supportive periodontal therapy. J Periodontal Implant Sci. 2018 Aug 31;48(4):251-260. doi: 10.5051/jpis.2018.48.4.251. eCollection 2018 Aug.

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    2019-01-15 feather89
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    2019-02-04 xuyu
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    2019-04-07 xuyong536
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