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JAHA:长QT间期是冠心病女性患者心源性猝死的独立预测因素

2017-08-27 MedSci MedSci原创

心源性猝死(SCD)常常是缺血性心脏病的首要表现,然而,目前尚缺乏SCD在患有梗阻性冠心病和没有梗阻性冠心病女性患者中关系的相关研究。本研究共纳入了904名患有缺血性心脏病伴保留型射血分数的女性患者,并对其冠脉造影结果进行了随访。一旦出现患者死亡,便会有专业的医生进行鉴定并开具死亡证明。临床事件委员会将对心源性死亡或非心源性死亡、SCD或非SCD进行鉴定。最终,经过平均6年的随访,96名(11%)

心源性猝死(SCD)常常是缺血性心脏病的首要表现,然而,目前尚缺乏SCD在患有梗阻性冠心病和没有梗阻性冠心病女性患者中关系的相关研究。本研究共纳入了904名患有缺血性心脏病伴保留型射血分数的女性患者,并对其冠脉造影结果进行了随访。一旦出现患者死亡,便会有专业的医生进行鉴定并开具死亡证明。临床事件委员会将对心源性死亡或非心源性死亡、SCD或非SCD进行鉴定。最终,经过平均6年的随访,96名(11%)患者死亡,在65例心源性死亡中,42%为SCD。并且,每人时的死亡率随着冠心病的严重程度呈直线上升(无冠心病:5.8;轻度冠心病:15.9;梗阻性冠心病:38.6;P<0.0001)。然而,SCD所占的比例在各冠心病严重程度的患者中是相似的(40%, 58%, 38%)。此外,考虑上传统的危险因素(年龄、糖尿病、抽烟),伴有抑郁疾病史和长的QT间期是SCD的独立预测因子,而在无梗阻性冠心病的女性患者中,长的QT间期是SCD的独立预测因子。研究结果表明,在伴或不伴有梗阻性冠心病的女性患者中,心源性猝死占了死亡事件的一大部分。长QT间期是冠心病女性患者心源性猝死的独立预测因素。原始出处:Pu

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    2017-08-29 zhaohui6731
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    2017-08-29 xinmeili
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    2017-08-29 mhm295
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    2017-08-27 1e0f8808m18(暂无匿称)

    长QT间期对冠心病的预后预测.

    0

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    2017-08-27 飛歌

    厉害了我的哥

    0

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    2017-08-27 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

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