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Brit J Cancer：坚果摄入和食管鳞状细胞癌风险

2018-06-28 xing.T MedSci原创

坚果摄入食管鳞状细胞癌风险
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由此可见，该研究发现，在这些高风险人群中，坚果总消耗量与ESCC风险之间存在统计学显著的负相关性。

在美国的研究中，坚果消耗量与胃癌发病率呈负相关，但与食管癌无关。然而，在食管鳞状细胞癌（ESCC）低风险人群和高风险人群中存在病因异质性。近日，肿瘤领域权威杂志British Journal of Cancer上发表了一篇研究文章，该研究的目的是评估高风险人群中坚果消耗量与ESCC风险之间的关系。

2004年至2008年期间，Golestan队列研究共调查了在伊朗东北部的50045名参与者。在基线时，研究人员使用经验证的食物频率问卷评估了花生、核桃和混合坚果的摄入量。研究人员使用Cox比例风险模型估计了调整潜在混杂因素后ESCC的风险比（HR）和95％置信区间。以未摄入坚果的参与者作为参考组，并且将坚果摄入者摄入量的三分位数进行分组。

在337983人次每年的随访期间累计发生280例ESCC病例。与非摄入者相比，坚果总摄入量以及混合坚果摄入量最高三分位数的个体与较低的ESCC发生风险显著相关（HR=0.60,95％CI=0.39-0.93，趋势p=0.02，HR=0.52,95％CI=0.32-0.84，趋势p=0.002）。

由此可见，该研究发现，在这些高风险人群中，坚果总消耗量与ESCC风险之间存在统计学显著的负相关性。


原始出处：

Maryam Hashemian,et al. Nut consumption and the risk of oesophageal squamous cell carcinoma in the Golestan Cohort Study.British Journal of Cancer. 2018.https://www.nature.com/articles/s41416-018-0148-0

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    2019-06-12 qingting

    #细胞癌#

    0

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    2019-05-12 sjq027

    #癌风险#

    0

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    2018-08-28 执着追梦

    学习，谢谢分享

    0

  4. 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createdName=sjq027, createdTime=Sun May 12 05:57:00 CST 2019, time=2019-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=341443, encodeId=55eb34144325, content=学习，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Tue Aug 28 10:54:28 CST 2018, time=2018-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328561, encodeId=5b3c328561e6, content=可以.值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/CD9641ADF96717CB416B573C11E408F8/100, createdBy=989a2332121, createdName=hahalu, createdTime=Sun Jul 01 22:41:44 CST 2018, time=2018-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328560, encodeId=4575328560d1, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/CD9641ADF96717CB416B573C11E408F8/100, createdBy=989a2332121, createdName=hahalu, createdTime=Sun Jul 01 22:41:14 CST 2018, time=2018-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328159, encodeId=54f73281594d, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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level=null, likeNumber=180, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101129, encryptionId=b860101129ac, topicName=食管鳞状细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aae2431, createdName=venlin, createdTime=Sat Jun 30 05:57:00 CST 2018, time=2018-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437341, encodeId=e282143e34194, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sat Jun 30 05:57:00 CST 2018, time=2018-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328085, encodeId=a5103280853a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sat Jun 30 05:51:02 CST 2018, time=2018-06-30, status=1, ipAttribution=)]
    2018-07-01 hahalu

    可以.值得学习

    0

  5. 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level=null, likeNumber=180, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101129, encryptionId=b860101129ac, topicName=食管鳞状细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aae2431, createdName=venlin, createdTime=Sat Jun 30 05:57:00 CST 2018, time=2018-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437341, encodeId=e282143e34194, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sat Jun 30 05:57:00 CST 2018, time=2018-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328085, encodeId=a5103280853a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sat Jun 30 05:51:02 CST 2018, time=2018-06-30, status=1, ipAttribution=)]
    2018-07-01 hahalu

    学习了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1978707, encodeId=c04319e8707e8, content=<a href='/topic/show?id=3b90e79787f' target=_blank style='color:#2F92EE;'>#细胞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77978, encryptionId=3b90e79787f, topicName=细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e457184, createdName=qingting, createdTime=Wed Jun 12 07:57:00 CST 2019, time=2019-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061760, encodeId=ae3c2061e602c, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328085, encodeId=a5103280853a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sat Jun 30 05:51:02 CST 2018, time=2018-06-30, status=1, ipAttribution=)]
    2018-06-30 sunfeifeiyang

    学习

    0

  7. 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level=null, likeNumber=180, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101129, encryptionId=b860101129ac, topicName=食管鳞状细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aae2431, createdName=venlin, createdTime=Sat Jun 30 05:57:00 CST 2018, time=2018-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437341, encodeId=e282143e34194, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sat Jun 30 05:57:00 CST 2018, time=2018-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328085, encodeId=a5103280853a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sat Jun 30 05:51:02 CST 2018, time=2018-06-30, status=1, ipAttribution=)]
    2018-06-30 神功盖世

    学习

    0

  8. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328085, encodeId=a5103280853a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sat Jun 30 05:51:02 CST 2018, time=2018-06-30, status=1, ipAttribution=)]
    2018-06-30 venlin

    #食管鳞状细胞癌#

    0

  9. 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level=null, likeNumber=180, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101129, encryptionId=b860101129ac, topicName=食管鳞状细胞癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aae2431, createdName=venlin, createdTime=Sat Jun 30 05:57:00 CST 2018, time=2018-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1437341, encodeId=e282143e34194, content=<a href='/topic/show?id=0e311010591a' target=_blank style='color:#2F92EE;'>#食管#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101059, encryptionId=0e311010591a, topicName=食管)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sat Jun 30 05:57:00 CST 2018, time=2018-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328085, encodeId=a5103280853a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sat Jun 30 05:51:02 CST 2018, time=2018-06-30, status=1, ipAttribution=)]
    2018-06-30 zhouqu_8

    #食管#

    0

  10. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328085, encodeId=a5103280853a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/01/15/8213228fe923915543544ad3da7e1c64.jpg, createdBy=6bd82014262, createdName=秀红, createdTime=Sat Jun 30 05:51:02 CST 2018, time=2018-06-30, status=1, ipAttribution=)]
    2018-06-30 秀红

    学习了

    0

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