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AJG : 盐水灌注可降低胆总管残留率

2018-05-28 MedSci MedSci原创

在临床实践中,因为胆总管结石(CBD)残留经常会出现复发性胆管炎,甚至在内窥镜清除胆结石后也会频繁发生。本研究旨在确定内镜切除CBD结石后胆管预防性盐水灌注(PSIB)是否会减少残余的CBD结石。

背景及目的:在临床实践中,因为胆总管结石(CBD)残留经常会出现复发性胆管炎,甚至在内窥镜清除胆结石后也会频繁发生。本研究旨在确定内镜切除CBD结石后胆管预防性盐水灌注(PSIB)是否会减少残余的CBD结石。

方法:这是一项多中心,前瞻性,随机研究,接受内镜逆行胰胆管造影术切除CBD结石的患者被随机分组接受PSIB术后摘除结石(PSIB组)或未接受PSIB(非PSIB组)。研究人员对患者进行前瞻性随访,并在内窥镜结石清除后6个月内评估残余CBD结石的存在。

结果:共有148名患者入选并完成随访(PSIB组73名,非PSIB组75名)。两组在基线特征方面相似。22名患者(14.9%)检测到残余的CBD结石。PSIB组残余CBD结石发生率为6.8%,非PSIB组为22.7%(P= 0.010)。多变量分析显示,PSIB的表现和仅存在单一CBD结石是减少残余CBD结石发生率的重要因素。尽管PSIB组的手术时间略长(22.0 vs 19.2 min,P= 0.037),但两组之间在手术相关并发症方面没有显着差异。

结论:PSIB可以在不增加并发症的情况下减少残余的CBD结石。考虑到疗效和安全性,内镜下CBD结石清除后的常规PSIB似乎是首选治疗方案。

原始出处:

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    2019-01-21 minzju5052
  2. [GetPortalCommentsPageByObjectIdResponse(id=2057247, encodeId=9ab0205e2474c, content=<a href='/topic/show?id=18982222db' target=_blank style='color:#2F92EE;'>#AJG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2222, encryptionId=18982222db, topicName=AJG)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2978132, createdName=minzju5052, createdTime=Mon Jan 21 08:00:00 CST 2019, time=2019-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=319404, encodeId=b25b3194045f, content=学习了.获益匪浅.感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/02/27/c53a212859edcad4f60a54feffff50bb.jpg, createdBy=67cf1525321, createdName=13718711b3m, createdTime=Mon May 28 15:10:47 CST 2018, time=2018-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=319403, encodeId=3dec31940321, content=徐反反复复虢国夫人, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Mon May 28 15:09:40 CST 2018, time=2018-05-28, status=1, ipAttribution=)]
    2018-05-28 13718711b3m

    学习了.获益匪浅.感谢分享

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=2057247, encodeId=9ab0205e2474c, content=<a href='/topic/show?id=18982222db' target=_blank style='color:#2F92EE;'>#AJG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2222, encryptionId=18982222db, topicName=AJG)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2978132, createdName=minzju5052, createdTime=Mon Jan 21 08:00:00 CST 2019, time=2019-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=319404, encodeId=b25b3194045f, content=学习了.获益匪浅.感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/02/27/c53a212859edcad4f60a54feffff50bb.jpg, createdBy=67cf1525321, createdName=13718711b3m, createdTime=Mon May 28 15:10:47 CST 2018, time=2018-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=319403, encodeId=3dec31940321, content=徐反反复复虢国夫人, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Mon May 28 15:09:40 CST 2018, time=2018-05-28, status=1, ipAttribution=)]
    2018-05-28 为你把脉

    徐反反复复虢国夫人

    0

相关资讯

Am J Gastroenterology:盐水灌注降低胆总管残留率的多中心,前瞻性随机研究

在临床实践中,残留的胆总管结石(CBD)引起的复发性胆管炎甚至在内窥镜结石清除后仍频繁发生。本研究旨在确定内镜切除CBD结石后胆管预防性盐水灌注(PSIB)是否会减少残余的CBD结石。

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