Baidu
map

Crit Care Med:钩端螺旋体病的治疗现状如何?

2017-11-13 MedSci MedSci原创

钩端螺旋体病可以引起可逆的多器官功能衰竭,目前,其死亡率仍然很高。近期,一项发表在杂志Crit Care Med上的研究旨在确定在现今ICU提供的所有器官支持类型的条件下,钩端螺旋体病的死亡率,并将其与细菌性败血症的死亡率进行比较。此项研究为回顾性描述性和单中心队列研究。研究在留尼汪岛(印度洋)最大的一所教学医院ICU中进行。受试患者为2004年1月至2015年1月连续入住ICU的钩端螺旋体病患者

钩端螺旋体病可以引起可逆的多器官功能衰竭,目前,其死亡率仍然很高。


近期,一项发表在杂志Crit Care Med上的研究旨在确定在现今ICU提供的所有器官支持类型的条件下,钩端螺旋体病的死亡率,并将其与细菌性败血症的死亡率进行比较。

此项研究为回顾性描述性和单中心队列研究。研究在留尼汪岛(印度洋)最大的一所教学医院ICU中进行。受试患者为2004年1月至2015年1月连续入住ICU的钩端螺旋体病患者。

此项研究共报告了134例ICU住院的钩端螺旋体病患者。中位年龄为40岁(四分位间距,30-52岁),简易急性生理评分II为38分(27-50),序贯性器官衰竭评估评分为10分(8-12)。 41名患者(31%)需要机械通气,76名(56%)需要肾脏替代治疗。门-肾替代治疗时间为入院0(0-1)天,尿素中位数为25 mmol/L(17-32 mmol/L)。

五名患者需要体外膜式氧合。死亡率为6.0%(95%CI,2.6-11.4)。在脓毒症住院患者中,钩端螺旋体病患者的简化急性生理评分II的标准化死亡率显着低于0.40(95%CI,0.17 - 0.79)。

此项研究结果表明:现代复苏技术的支持使得重度钩端螺旋体病的死亡率低于其他细菌感染

原始出处:
Delmas B, Jabot J, et al. Leptospirosis in ICU: A Retrospective Study of 134 Consecutive Admissions. Crit Care Med. 2017 Nov 7. doi: 10.1097/CCM.0000000000002825. 

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (3)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2019455, encodeId=57302019455ed, content=<a href='/topic/show?id=e19b646e254' target=_blank style='color:#2F92EE;'>#治疗现状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64672, encryptionId=e19b646e254, topicName=治疗现状)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/4v5DMqK7WnzoBdibNsryQ8OEM5gFSdRH9j3HNCKPfKXlObInweOSHdQPATeTicYp7nvg3bsgicjLgRkdlhrpry21w/132, createdBy=6bf82500013, createdName=ms5822920152752585, createdTime=Sun May 06 02:37:00 CST 2018, time=2018-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608239, encodeId=94001608239a5, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Wed Nov 15 10:37:00 CST 2017, time=2017-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261083, encodeId=b2722610839a, content=好资料学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Nov 13 22:01:10 CST 2017, time=2017-11-13, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2019455, encodeId=57302019455ed, content=<a href='/topic/show?id=e19b646e254' target=_blank style='color:#2F92EE;'>#治疗现状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64672, encryptionId=e19b646e254, topicName=治疗现状)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/4v5DMqK7WnzoBdibNsryQ8OEM5gFSdRH9j3HNCKPfKXlObInweOSHdQPATeTicYp7nvg3bsgicjLgRkdlhrpry21w/132, createdBy=6bf82500013, createdName=ms5822920152752585, createdTime=Sun May 06 02:37:00 CST 2018, time=2018-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608239, encodeId=94001608239a5, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Wed Nov 15 10:37:00 CST 2017, time=2017-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261083, encodeId=b2722610839a, content=好资料学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Nov 13 22:01:10 CST 2017, time=2017-11-13, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2019455, encodeId=57302019455ed, content=<a href='/topic/show?id=e19b646e254' target=_blank style='color:#2F92EE;'>#治疗现状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64672, encryptionId=e19b646e254, topicName=治疗现状)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/4v5DMqK7WnzoBdibNsryQ8OEM5gFSdRH9j3HNCKPfKXlObInweOSHdQPATeTicYp7nvg3bsgicjLgRkdlhrpry21w/132, createdBy=6bf82500013, createdName=ms5822920152752585, createdTime=Sun May 06 02:37:00 CST 2018, time=2018-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608239, encodeId=94001608239a5, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Wed Nov 15 10:37:00 CST 2017, time=2017-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=261083, encodeId=b2722610839a, content=好资料学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Nov 13 22:01:10 CST 2017, time=2017-11-13, status=1, ipAttribution=)]
    2017-11-13 thlabcde

    好资料学习了!

    0

Baidu
map
Baidu
map
Baidu
map