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J Intern Med:亚洲阿尔茨海默病和脑血管病共存的专家共识

2016-09-28 Moon 译 MedSci原创

学术界越来越多的人意识到阿尔茨海默病和脑血管病(AD+CVD)的共存,但是由于尚缺乏明确的诊断标准和治疗指南,所以亚洲的AD+CVD患者可能被低估。 来自9个亚太地区国家的16名老年痴呆症专家在2014年9月完成了一项调查,并于2014年11月进行会面,回顾亚洲AD+CVD的流行病学、诊断和治疗方法。通过讨论得出共识,已发表的文献为共识提供证据支持。 数据显示,所有亚洲痴呆症患者中,A

学术界越来越多的人意识到阿尔茨海默病和脑血管病(AD+CVD)的共存,但是由于尚缺乏明确的诊断标准和治疗指南,所以亚洲的AD+CVD患者可能被低估。

来自9个亚太地区国家的16名老年痴呆症专家在2014年9月完成了一项调查,并于2014年11月进行会面,回顾亚洲AD+CVD的流行病学、诊断和治疗方法。通过讨论得出共识,已发表的文献为共识提供证据支持。

数据显示,所有亚洲痴呆症患者中,AD高达60%,AD+CVD占了10-20%。漏诊AD+CVD的原因包括:因缺乏诊断标准而缺乏相关意识、误诊为血管性痴呆或AD、缺乏诊断设施、资源限制和检查费用。在临床实践中,用于诊断AD+CVD的工具存在变异性。诊断AD+CVD应该逐步进行临床评估,其次是进行神经影像学检查。应对老年痴呆症患者的认知、行为和心理症状、功能性分期和工具性日常生活活动进行评估。神经影像学检查设备包括计算机断层扫描或磁共振成像。以稳定或缓慢进展、减少行为和心理症状、提高生活质量、减轻疾病负担为治疗目标。通常使用乙酰胆碱酯酶抑制剂多奈哌齐等作为一线治疗药物。

在亚洲,AD+CVD并没有得到很好的认识,并且可能低估该疾病。未来需要进一步的研究,以建立真正AD+CVD患病率、治疗方式和潜在预防方式等。

原始出处:

C. Chen,et al.Alzheimer's disease with cerebrovascular disease: current status in the Asia–Pacific region.J Intern Med.Volume 280, Issue 4.October 2016

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  5. 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    2016-10-02 1e0ef05cm88(暂无匿称)

    这是一个新观点

    0

  6. 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  7. 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createdTime=Fri Sep 30 09:00:00 CST 2016, time=2016-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=137544, encodeId=994a13e544d2, content=好学习了谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQpl0ENSJScphsFtdgfibXX1g1IuEYGCjP23UqCd52TxTpSZibtPiclyusaHicnNXd78alaia19Qy1nAFo18/0, createdBy=50381491660, createdName=zwjnj2, createdTime=Thu Sep 29 07:31:08 CST 2016, time=2016-09-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=137301, encodeId=c8e413e301cc, content=学术界越来越多的人意识到阿尔茨海默病和脑血管病(AD+CVD)的共存,, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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  8. 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createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Wed Sep 28 20:40:11 CST 2016, time=2016-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=137300, encodeId=4f5e13e3004f, content=继续关注!, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Wed Sep 28 20:39:34 CST 2016, time=2016-09-28, status=1, ipAttribution=)]
    2016-09-29 zwjnj2

    好学习了谢谢

    0

  9. 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createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Wed Sep 28 20:40:11 CST 2016, time=2016-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=137300, encodeId=4f5e13e3004f, content=继续关注!, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Wed Sep 28 20:39:34 CST 2016, time=2016-09-28, status=1, ipAttribution=)]
    2016-09-28 知难而进

    学术界越来越多的人意识到阿尔茨海默病和脑血管病(AD+CVD)的共存,

    0

  10. 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style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=64bb23195917, createdName=Luyuxie_17, createdTime=Sat Nov 05 15:00:00 CST 2016, time=2016-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=138817, encodeId=ed6013881efc, content=这是一个新观点, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160822/IMG57BB02252E6F45704.jpg, createdBy=02af1940795, createdName=1e0ef05cm88(暂无匿称), createdTime=Sun Oct 02 07:31:44 CST 2016, time=2016-10-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1470094, 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createdTime=Fri Sep 30 09:00:00 CST 2016, time=2016-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=137544, encodeId=994a13e544d2, content=好学习了谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQpl0ENSJScphsFtdgfibXX1g1IuEYGCjP23UqCd52TxTpSZibtPiclyusaHicnNXd78alaia19Qy1nAFo18/0, createdBy=50381491660, createdName=zwjnj2, createdTime=Thu Sep 29 07:31:08 CST 2016, time=2016-09-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=137301, encodeId=c8e413e301cc, content=学术界越来越多的人意识到阿尔茨海默病和脑血管病(AD+CVD)的共存,, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Wed Sep 28 20:40:11 CST 2016, time=2016-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=137300, encodeId=4f5e13e3004f, content=继续关注!, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Wed Sep 28 20:39:34 CST 2016, time=2016-09-28, status=1, ipAttribution=)]
    2016-09-28 知难而进

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