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Stroke:高血压患者血浆锌水平与首次卒中风险

2019-08-26 xing.T MedSci原创

由此可见,在高血压患者中,研究人员发现血浆锌水平与首次出血性卒中之间存在显著的负相关。

近日,心血管疾病领域权威杂志Stroke上发表了一篇研究文章,研究人员旨在评估高血压患者基线血浆锌水平与首次卒中风险之间的关系,并探究任何可能的效应调节因子。

研究人群来自CSPPT(中国卒中一级预防试验),研究人员采用嵌套病例对照设计,纳入了599例首次卒中病例和599例匹配对照者。 

与基线血浆锌<106.9g/dL(中位数)的参与者相比,血浆锌为106.9 g/dL的患者首次出血性卒中风险显著降低(多变量校正比值比为0.45; 95%CI为0.210-0.94)。此外,在基线体重指数为25.0 kg/m2或血浆铜<100.1 g/dL的参与者中,血浆锌水平与首次出血性卒中之间负相关性显著增强(两个变量的相互作用P<0.05)。然而,血浆锌水平与首次缺血性卒中之间无显著相关性(<103.3 vs. 103.3 g/dL[中位数];多变量校正比值比为1.16; 95%CI为0.83-1.61)。

由此可见,在高血压患者中,研究人员发现血浆锌水平与首次出血性卒中之间存在显著的负相关。  

原始出处:

Jingping Zhang.et al.Baseline Plasma Zinc and Risk of First Stroke in Hypertensive Patients A Nested Case-Control Study.stroke.2019.https://www.ahajournals.org/doi/10.1161/STROKEAHA.119.027003

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    2019-08-26 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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    2019-08-26 guging

    中风是俗称,应该称为缺血性卒中吧

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2066136, encodeId=14fb2066136d8, content=<a href='/topic/show?id=1863892267e' target=_blank style='color:#2F92EE;'>#血浆锌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89226, encryptionId=1863892267e, topicName=血浆锌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc4b2500077, createdName=hittouch, createdTime=Sat Oct 05 17:23:00 CST 2019, time=2019-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281320, encodeId=7d6a128132042, content=<a href='/topic/show?id=455f36085f0' target=_blank style='color:#2F92EE;'>#卒中风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f1167, createdName=wmr111, createdTime=Wed Aug 28 11:23:00 CST 2019, time=2019-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1448285, encodeId=33a5144828582, content=<a href='/topic/show?id=5a9c102681f2' target=_blank style='color:#2F92EE;'>#高血压患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102681, encryptionId=5a9c102681f2, topicName=高血压患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4665409655, createdName=维他命, createdTime=Wed Aug 28 11:23:00 CST 2019, time=2019-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026441, encodeId=e398102644137, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Mon Aug 26 23:23:00 CST 2019, time=2019-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1045886, encodeId=748c104588606, content=中风是俗称,应该称为缺血性卒中吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=guging, createdTime=Mon Aug 26 23:23:00 CST 2019, time=2019-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371836, encodeId=90ab3e1836bd, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Mon Aug 26 20:58:00 CST 2019, time=2019-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371835, encodeId=910c3e1835a5, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Mon Aug 26 20:40:08 CST 2019, time=2019-08-26, status=1, ipAttribution=)]
    2019-08-26 天地飞扬

    学习

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2066136, encodeId=14fb2066136d8, content=<a href='/topic/show?id=1863892267e' target=_blank style='color:#2F92EE;'>#血浆锌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89226, encryptionId=1863892267e, topicName=血浆锌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc4b2500077, createdName=hittouch, createdTime=Sat Oct 05 17:23:00 CST 2019, time=2019-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281320, encodeId=7d6a128132042, content=<a href='/topic/show?id=455f36085f0' target=_blank style='color:#2F92EE;'>#卒中风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36085, encryptionId=455f36085f0, topicName=卒中风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f1167, createdName=wmr111, createdTime=Wed Aug 28 11:23:00 CST 2019, time=2019-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1448285, encodeId=33a5144828582, content=<a href='/topic/show?id=5a9c102681f2' target=_blank style='color:#2F92EE;'>#高血压患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102681, encryptionId=5a9c102681f2, topicName=高血压患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b4665409655, createdName=维他命, createdTime=Wed Aug 28 11:23:00 CST 2019, time=2019-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026441, encodeId=e398102644137, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Mon Aug 26 23:23:00 CST 2019, time=2019-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1045886, encodeId=748c104588606, content=中风是俗称,应该称为缺血性卒中吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=guging, createdTime=Mon Aug 26 23:23:00 CST 2019, time=2019-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371836, encodeId=90ab3e1836bd, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Mon Aug 26 20:58:00 CST 2019, time=2019-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371835, encodeId=910c3e1835a5, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Mon Aug 26 20:40:08 CST 2019, time=2019-08-26, status=1, ipAttribution=)]
    2019-08-26 医者仁心5538

    学习了

    0

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