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JACC- Heart Failure:有氧运动为心力衰竭患者带来获益

2018-12-14 国际循环编辑部 国际循环

基线体力活动(PA)对慢性心力衰竭(HF)患者的运动能力,运动训练反应和临床结局的影响尚不清楚。近日,JACC: Heart Failure的一项研究旨在评估基线PA对慢性收缩性HF门诊患者有氧运动训练和临床事件的影响。

基线体力活动(PA)对慢性心力衰竭(HF)患者的运动能力,运动训练反应和临床结局的影响尚不清楚。近日,JACC: Heart Failure的一项研究旨在评估基线PA对慢性收缩性HF门诊患者有氧运动训练和临床事件的影响。

研究纳入2130名参与者,使用修订版国际体育活动问卷——简表形式,最终获得1494例患者(64%)的完整基线PA数据,并纳入分析;742人接受常规护理,752人分配到运动训练组。运动能力,全因死亡率和住院率,血管(CV)死亡率和住院率,CV死亡率和HF住院率的变化作为基线PA三分位数的评估指数。



研究结果,基线时,最高PA三分位数显示出比其他2个PA三分位数更高的峰值氧摄取,心肺运动测试持续时间和6 min步行试验,以及更低的NYHA心功能分级,更低的Beck抑郁评分,以及低于最低PA三分位数的低心房颤动患病率。与最低PA三分位数相比,中间三分位数的CV死亡/CV住院风险降低18%,并且较高三分位数显示CV死亡/HF住院治疗的风险降低23%。运动能力和运动训练反应的临床结局相似,并且基线PA三分位数方面基本无显著性,对所有三分位数运动测试持续时间的训练具有显著获益。

研究证实,在慢性收缩期HF患者中,有氧运动训练显著改善基线PA三分位数的运动试验持续时间。虽然,较高的基线PA与较低的临床事件风险相关,但在随机分配到运动训练与常规护理的亚组之间,每个PA三分位数的事件发生率无显著差异。

原始出处:
Mauro F.F. Mediano, Eric S. Leifer, Lawton S. Cooper, et al. Influence of Baseline Physical Activity Level on Exercise Training Response and Clinical Outcomes in Heart Failure. JACC: Heart Failure. December 2018.

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    2019-01-23 hbwxf
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    2019-04-29 amy0550
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    2018-12-16 zhaojie88
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    2018-12-16 slcumt
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    2018-12-15 topnew

    运动是良医

    0

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    2018-12-15 明天jing

    有氧运动与无氧运动应该一直有争议,二者对健康的作用有差别,但是也应该有度(时间)的关系,过度运动可能并不合适,尤其是无氧运动。

    0

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