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Stroke: 前循环中的血流动力学标记可以作为颅内狭窄患者复发性卒中的预测因子

2019-01-13 MedSci MedSci原创

虽然前期研究文献中表明颅内狭窄的患者进行积极的药物治疗优于支架术,但药物使用的卒中率仍然很高。因此,本研究的目的是确定有颅内狭窄风险患者的血流动力学标志物与复发性卒中发生率之间的关系。

背景和目的
虽然前期研究文献中表明颅内狭窄的患者进行积极的药物治疗优于支架术,但药物使用的卒中率仍然很高。因此,本研究的目的是确定有颅内狭窄风险患者的血流动力学标志物与复发性卒中发生率之间的关系。

方法
本项研究是一项回顾性研究,对大脑中动脉或颅内颈动脉区域梗塞的患者进行回顾性分析。梗塞被判定为主要涉及内部或皮质边界区域,核心大脑中动脉区域或穿孔区域,并且根据标准尺度评估侧支血流。

结果
本项研究共纳入101名符合条件的患者,14名患者(26.4%)患有边缘区梗塞,2名(8.3%)患有核心大脑中动脉梗塞,3名(12.5%)患有穿孔梗死。82例侧支血流评估患者中,30例中有70%的患者伴有边缘区梗塞,19例中有7例(37%)患有核心大脑中动脉梗塞,20例中有11例(55%)伴有穿孔梗死,侧支血流受损。狭窄,边界区梗塞和侧支血流受损的患者卒中复发的风险最高。

结论
边界区梗塞和侧支血流受损的患者在治疗时卒中复发的风险特别高。

原始出处:

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    2019-01-15 ylzr123

    认真学习,不断进步,把经验分享给同好。点赞了!

    0

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    2019-01-13 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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