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JAMA:静脉曲张与静脉血栓栓塞及周围动脉疾病的关系

2018-03-01 zhangfan MedSci原创

研究认为,静脉曲张导致深静脉血栓风险显著增加,但静脉曲张与深静脉血栓之间的联系是否是因果关系,还是代表了一组共同的危险因素,还需要进一步的研究

静脉曲张是一种常见病,很少导致严重的健康风险,而深静脉血栓 (DVT)、肺栓塞(PE)和周围动脉疾病(PAD)也是血管性疾病,却是危险的健康杀手。近日研究人员考察了静脉曲张与DVT、PE或PAD风险之间的相关性。

研究考察了台湾国民健康保险数据,20岁以上的静脉曲张患者参与研究,以非静脉曲张患者作为对照,考察二者DVT, PE以及PAD的发病风险差异。

212984名静脉曲张患者以及志愿者参与研究,组间人口统计学数据差异不显著,对DVT、PE以及PAD分别随访7.5-7.6、7.7-7.8以及7.3-7.4年。研究发现,静脉曲张组患者DVT(每1000患者年6.65vs1.23例;发病数10360 vs 1980;绝对差异5.32)发病率显著增加,而PE(0.48 vs 0.28例;793 vs 451例;0.20)以及PAD(10.73 vs 6.22例;16615 vs 9709例;4.51)发病率增加。静脉曲张患者DVT、PE以及PAD的发病风险分别为5.30、1.73以及1.72。

研究认为,静脉曲张导致深静脉血栓风险显著增加,但静脉曲张与深静脉血栓之间的联系是否是因果关系,还是代表了一组共同的危险因素,还需要进一步的研究。

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    2019-08-16 1257202em47暂无昵称

    台湾国民?确定这不是台独言论?

    0

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    2019-01-06 xue8602
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    2018-03-09 fusion
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    2018-03-04 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

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