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欧盟对Trovagene的PCM-075孤儿药物认定持积极意见

2018-08-02 MedSci MedSci原创

PCM-075Trovagene孤儿药物认定
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Trovagene制药是一家专业肿瘤治疗公司，正开发用于治疗白血病/淋巴瘤和实体瘤癌症的靶向疗法，Trovagene制药近日宣布欧洲药品管理局（EMA）孤儿药品委员会（COMP）已对PCM-075采纳积极意见，建议将PCM-075指定为治疗急性髓性白血病（AML）的孤儿药

Trovagene制药是一家专业肿瘤治疗公司，正开发用于治疗白血病/淋巴瘤和实体瘤癌症的靶向疗法，Trovagene制药近日宣布欧洲药品管理局（EMA）孤儿药品委员会（COMP）已对PCM-075采纳积极意见，建议将PCM-075指定为治疗急性髓性白血病（AML）的孤儿药。PCM-075是的第三代高选择性口服Polo Like Kinase 1（PLK1）抑制剂，旨在控制细胞分裂（有丝分裂）。

Trovagene董事长兼首席执行官Thomas Adams博士说：“EMAs孤儿药品委员会的积极意见是基于PCM-075体内数据的显著优势，标志着我们改善AML患者生活的又一个里程碑。我们相信PCM-075与标准治疗药物和靶向疗法相结合有可能在AML患者的疗效和安全性方面提供显著的临床益处”。

要获得欧盟的孤儿药物认定，公司必须提供数据证明在治疗疾病时使用研究性疗法的合理性，并确定该药物有可能为患者提供相关优势或对患者护理做出重大贡献现。COMP向Trovagene发出的意见书称：“尽管欧盟已经批准了其他令人满意的治疗方法，但PCM-075对AML患者仍将具有显著益处”。


原始出处：

http://www.firstwordpharma.com/node/1582388#axzz5Mw2WiygQ

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    2018-11-07 lfcmxl

    #Trovagene#

    0

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    2019-01-03 gujh

    #PCM-075#

    0

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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Thu Aug 02 22:28:19 CST 2018, time=2018-08-02, status=1, ipAttribution=)]
    2019-03-19 cy0324

    #Gene#

    0

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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Fri Aug 03 00:10:22 CST 2018, time=2018-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335865, encodeId=32b6335865b2, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu Aug 02 22:58:54 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335850, encodeId=919833585037, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Thu Aug 02 22:28:19 CST 2018, time=2018-08-02, status=1, ipAttribution=)]
    2018-11-08 ms6980045490879608

    #孤儿药物#

    0

  5. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Fri Aug 03 00:10:22 CST 2018, time=2018-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335865, encodeId=32b6335865b2, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu Aug 02 22:58:54 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335850, encodeId=919833585037, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Thu Aug 02 22:28:19 CST 2018, time=2018-08-02, status=1, ipAttribution=)]
    2018-10-03 yjs木玉

    好好好好好好好好

    0

  6. 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attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sat Aug 04 21:29:23 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615954, encodeId=f6b9161595449, content=<a href='/topic/show?id=519345433ea' target=_blank style='color:#2F92EE;'>#孤儿药物认定#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45433, encryptionId=519345433ea, topicName=孤儿药物认定)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Sat Aug 04 12:09:00 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335888, encodeId=9b9d33588871, content=厉害了我的妹, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Fri Aug 03 00:10:22 CST 2018, time=2018-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335865, encodeId=32b6335865b2, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu Aug 02 22:58:54 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335850, encodeId=919833585037, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Thu Aug 02 22:28:19 CST 2018, time=2018-08-02, status=1, ipAttribution=)]
    2018-08-04 天地飞扬

    了解一下，谢谢分享！

    0

  7. 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attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sat Aug 04 21:29:23 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615954, encodeId=f6b9161595449, content=<a href='/topic/show?id=519345433ea' target=_blank style='color:#2F92EE;'>#孤儿药物认定#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45433, encryptionId=519345433ea, topicName=孤儿药物认定)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Sat Aug 04 12:09:00 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335888, encodeId=9b9d33588871, content=厉害了我的妹, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Fri Aug 03 00:10:22 CST 2018, time=2018-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335865, encodeId=32b6335865b2, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu Aug 02 22:58:54 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335850, encodeId=919833585037, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Thu Aug 02 22:28:19 CST 2018, time=2018-08-02, status=1, ipAttribution=)]
    2018-08-04 仁医06

    #孤儿药物认定#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2049788, encodeId=a65f2049e8877, content=<a href='/topic/show?id=05ea1e8500a' target=_blank style='color:#2F92EE;'>#Trovagene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17850, encryptionId=05ea1e8500a, topicName=Trovagene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da20314, createdName=lfcmxl, createdTime=Wed Nov 07 01:09:00 CST 2018, time=2018-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2043797, encodeId=01b32043e9789, content=<a href='/topic/show?id=2df51385847' target=_blank style='color:#2F92EE;'>#PCM-075#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13858, encryptionId=2df51385847, topicName=PCM-075)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3333505, createdName=gujh, createdTime=Thu Jan 03 19:09:00 CST 2019, time=2019-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2049066, encodeId=46052049066ef, content=<a href='/topic/show?id=4363e929ad' target=_blank style='color:#2F92EE;'>#Gene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7929, encryptionId=4363e929ad, topicName=Gene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Tue Mar 19 00:09:00 CST 2019, time=2019-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1740082, encodeId=3bd41e4008205, content=<a href='/topic/show?id=f5a445431df' target=_blank style='color:#2F92EE;'>#孤儿药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45431, encryptionId=f5a445431df, topicName=孤儿药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a4f034650217, createdName=ms6980045490879608, createdTime=Thu Nov 08 18:09:00 CST 2018, time=2018-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=347709, encodeId=d06534e7099a, content=好好好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Wed Oct 03 06:08:21 CST 2018, time=2018-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336422, encodeId=2cdf336422f9, content=了解一下，谢谢分享！, beContent=null, objectType=article, channel=null, level=null, likeNumber=157, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sat Aug 04 21:29:23 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615954, encodeId=f6b9161595449, content=<a href='/topic/show?id=519345433ea' target=_blank style='color:#2F92EE;'>#孤儿药物认定#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45433, encryptionId=519345433ea, topicName=孤儿药物认定)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Sat Aug 04 12:09:00 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335888, encodeId=9b9d33588871, content=厉害了我的妹, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Fri Aug 03 00:10:22 CST 2018, time=2018-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335865, encodeId=32b6335865b2, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu Aug 02 22:58:54 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335850, encodeId=919833585037, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Thu Aug 02 22:28:19 CST 2018, time=2018-08-02, status=1, ipAttribution=)]
    2018-08-03 飛歌

    厉害了我的妹

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=2049788, encodeId=a65f2049e8877, content=<a href='/topic/show?id=05ea1e8500a' target=_blank style='color:#2F92EE;'>#Trovagene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17850, encryptionId=05ea1e8500a, topicName=Trovagene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da20314, createdName=lfcmxl, createdTime=Wed Nov 07 01:09:00 CST 2018, time=2018-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2043797, encodeId=01b32043e9789, content=<a href='/topic/show?id=2df51385847' target=_blank style='color:#2F92EE;'>#PCM-075#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13858, encryptionId=2df51385847, topicName=PCM-075)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3333505, createdName=gujh, createdTime=Thu Jan 03 19:09:00 CST 2019, time=2019-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2049066, encodeId=46052049066ef, content=<a href='/topic/show?id=4363e929ad' target=_blank style='color:#2F92EE;'>#Gene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7929, encryptionId=4363e929ad, topicName=Gene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Tue Mar 19 00:09:00 CST 2019, time=2019-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1740082, encodeId=3bd41e4008205, content=<a href='/topic/show?id=f5a445431df' target=_blank style='color:#2F92EE;'>#孤儿药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45431, encryptionId=f5a445431df, topicName=孤儿药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a4f034650217, createdName=ms6980045490879608, createdTime=Thu Nov 08 18:09:00 CST 2018, time=2018-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=347709, encodeId=d06534e7099a, content=好好好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Wed Oct 03 06:08:21 CST 2018, time=2018-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336422, encodeId=2cdf336422f9, content=了解一下，谢谢分享！, beContent=null, objectType=article, channel=null, level=null, likeNumber=157, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sat Aug 04 21:29:23 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615954, encodeId=f6b9161595449, content=<a href='/topic/show?id=519345433ea' target=_blank style='color:#2F92EE;'>#孤儿药物认定#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45433, encryptionId=519345433ea, topicName=孤儿药物认定)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Sat Aug 04 12:09:00 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335888, encodeId=9b9d33588871, content=厉害了我的妹, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Fri Aug 03 00:10:22 CST 2018, time=2018-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335865, encodeId=32b6335865b2, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu Aug 02 22:58:54 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335850, encodeId=919833585037, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Thu Aug 02 22:28:19 CST 2018, time=2018-08-02, status=1, ipAttribution=)]
    2018-08-02 1e1b8538m79(暂无匿称)

    不错的文章值得拥有哦

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=2049788, encodeId=a65f2049e8877, content=<a href='/topic/show?id=05ea1e8500a' target=_blank style='color:#2F92EE;'>#Trovagene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17850, encryptionId=05ea1e8500a, topicName=Trovagene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da20314, createdName=lfcmxl, createdTime=Wed Nov 07 01:09:00 CST 2018, time=2018-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2043797, encodeId=01b32043e9789, content=<a href='/topic/show?id=2df51385847' target=_blank style='color:#2F92EE;'>#PCM-075#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13858, encryptionId=2df51385847, topicName=PCM-075)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3333505, createdName=gujh, createdTime=Thu Jan 03 19:09:00 CST 2019, time=2019-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2049066, encodeId=46052049066ef, content=<a href='/topic/show?id=4363e929ad' target=_blank style='color:#2F92EE;'>#Gene#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7929, encryptionId=4363e929ad, topicName=Gene)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Tue Mar 19 00:09:00 CST 2019, time=2019-03-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1740082, encodeId=3bd41e4008205, content=<a href='/topic/show?id=f5a445431df' target=_blank style='color:#2F92EE;'>#孤儿药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45431, encryptionId=f5a445431df, topicName=孤儿药物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a4f034650217, createdName=ms6980045490879608, createdTime=Thu Nov 08 18:09:00 CST 2018, time=2018-11-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=347709, encodeId=d06534e7099a, content=好好好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=133, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Wed Oct 03 06:08:21 CST 2018, time=2018-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336422, encodeId=2cdf336422f9, content=了解一下，谢谢分享！, beContent=null, objectType=article, channel=null, level=null, likeNumber=157, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sat Aug 04 21:29:23 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1615954, encodeId=f6b9161595449, content=<a href='/topic/show?id=519345433ea' target=_blank style='color:#2F92EE;'>#孤儿药物认定#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45433, encryptionId=519345433ea, topicName=孤儿药物认定)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Sat Aug 04 12:09:00 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335888, encodeId=9b9d33588871, content=厉害了我的妹, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Fri Aug 03 00:10:22 CST 2018, time=2018-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335865, encodeId=32b6335865b2, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Thu Aug 02 22:58:54 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335850, encodeId=919833585037, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Thu Aug 02 22:28:19 CST 2018, time=2018-08-02, status=1, ipAttribution=)]
    2018-08-02 医者仁心5538

    学习了

    0

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